Browse Items (20 total)
- Tags: Messenger/metabolism
Tags: *Neuroinflammation, *Parkinson's disease, 1-Methyl-4-phenyl-1, 2, 2018, 3, 6-tetrahydropyridine/pharmacology, Analysis of Variance, Animals, Anti-Inflammatory Agents/*therapeutic use, Astrocyte, Astrocytes/*drug effects, Boyle Alexa M, Budge Kevin M, Case-Control Studies, CD44, Cells, Chemical, Cultured, Cytokines/genetics/metabolism, Databases, Female, Glial Fibrillary Acidic Protein/metabolism, GPNMB, Humans, Hyaluronan Receptors/*metabolism, Inflammation/*drug therapy/etiology, Journal of neuroinflammation, Male, Membrane Glycoproteins/*therapeutic use, Messenger/metabolism, Mice, Neal Matthew L, Neurotoxins/toxicity, Nitric Oxide/metabolism, Parkinson Disease/complications/*pathology, Reactive Oxygen Species/metabolism, Richardson Jason R, RNA, Safadi Fayez F, Signal Transduction/drug effects
Tags: 1989, Ahmad I, Animals, Carrillo A J, DNA Probes, Female, Finkelstein J A, Male, Messenger/metabolism, Molecular and cellular endocrinology, Nucleic Acid Hybridization, Obesity/*genetics/metabolism, Prolactin/genetics, Rats, RNA, Sex Characteristics, Somatomedins/*genetics, Steggles A W, Zucker
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis.
Tags: 2012, Animals, Anticarcinogenic Agents/pharmacology/*therapeutic use, Awale Prabha, Bhatia Deepak, Bishayee Anupam, Carroll Richard T, Current pharmaceutical biotechnology, Cytokines/genetics/*metabolism, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Experimental/chemically induced/metabolism/*prevention & control, Female, Geldenhuys Werner J, Gene Expression Regulation/drug effects, Liver Neoplasms, Liver/drug effects/metabolism, Mbimba Thomas, Messenger/metabolism, NEOMED College of Pharmacy, Phenobarbital, Rats, Resveratrol, RNA, Sprague-Dawley, Stilbenes/pharmacology/*therapeutic use
Tags: *Gene Expression Regulation, 2010, Acetylation, AMP-Activated Protein Kinases/metabolism, ATP Citrate (pro-S)-Lyase/genetics/metabolism, Bile Acids and Salts/metabolism, Cells, Chanda Dipanjan, Chiang John Y L, Choi Hueng-Sik, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, DNA-Binding Proteins/metabolism, Enzymologic, Epigenesis, Genes, Genetic, Glucose/*administration & dosage, Hep G2 Cells, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/*enzymology/metabolism, Histones/metabolism, Humans, Hyperglycemia/enzymology/*metabolism, Journal of lipid research, Li Tiangang, Messenger/metabolism, Methylation, NEOMED College of Medicine, Reporter, RNA, RNA Interference, Zhang Yanqiao
Tags: *RNA Interference, 2008, Animals, Biological Transport/drug effects, Cells, Cultured, Cystic Fibrosis Transmembrane Conductance Regulator/*genetics/*metabolism, Epithelial Sodium Channels/genetics/metabolism, Female, Folkesson Hans G, Gene Expression Regulation/drug effects, Koshy Shyny, Li Tianbo, Lung/cytology/drug effects/*metabolism, Messenger/metabolism, Newborn, Pregnancy, Rats, Respiratory Mucosa/cytology/drug effects/metabolism, Respiratory research, RNA, Small Interfering/*pharmacology, Sprague-Dawley, Water/*metabolism
Analysis of osteopontin in mouse growth plate cartilage by application of laser capture microdissection and RT-PCR.
Tags: *Reverse Transcriptase Polymerase Chain Reaction, 2003, Animals, Articular/chemistry/cytology, Cartilage, Chondrocytes/chemistry, Connective tissue research, Gene Expression, Growth Plate/*chemistry/cytology, Hillyer Jennifer, Inbred C57BL, Jacquet Robin, Landis William J, Laser Therapy, Messenger/metabolism, Mice, Microdissection/*methods, Newborn, Non-programmatic, Osteopontin, RNA, Sialoglycoproteins/*analysis/genetics, Tibia, Zhang Jean
A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.
Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques
Bcl-2 positively regulates Sox9-dependent chondrocyte gene expression by suppressing the MEK-ERK1/2 signaling pathway.
Tags: *Gene Expression Regulation, 2005, Adenoviridae/genetics, Animals, Apoptosis, beta-Galactosidase/metabolism, Blotting, Butadienes/pharmacology, Caspase Inhibitors, Cell Differentiation, Cell Line, Chondrocytes/*metabolism, Collagen Type II/metabolism, Department of Anatomy & Neurobiology, Down-Regulation, Enzyme Inhibitors/pharmacology, Fibroblasts/metabolism, Fluorescence, Genetic, High Mobility Group Proteins/*metabolism, Horton Walter E Jr, Lac Operon, Luciferases/metabolism, MAP Kinase Kinase Kinases/*metabolism, McBurney Denise, Messenger/metabolism, Microscopy, Mitogen-Activated Protein Kinase 1/*metabolism, Mitogen-Activated Protein Kinase 3/*metabolism, NEOMED College of Medicine, NF-kappa B/metabolism, Nitriles/pharmacology, Phenotype, Phosphorylation, Promoter Regions, Protein Kinase C-alpha, Protein Kinase C/antagonists & inhibitors, Proteoglycans/metabolism, Proto-Oncogene Proteins c-bcl-2/*metabolism, Rats, Reverse Transcriptase Polymerase Chain Reaction, RNA, Signal Transduction, Small Interfering/metabolism, SOX9 Transcription Factor, Sprague-Dawley, The Journal of biological chemistry, Time Factors, Transcription, Transcription Factors/*metabolism, Transfection, Western, Yagi Rieko
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene.
Tags: 2007, Bile Acids and Salts/metabolism, Carcinoma, Cell Line, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics/*metabolism, Cultured, Department of Integrative Medical Sciences, Enzyme Inhibitors/pharmacology, Gastroenterology, Genetic/drug effects/*physiology, Hepatocellular/*metabolism/pathology, Hepatocyte Nuclear Factor 4/metabolism, Hepatocytes/drug effects/*metabolism/pathology, Humans, Hydroxamic Acids/pharmacology, Li Tiangang, Liver Neoplasms/*metabolism/pathology, Messenger/metabolism, NEOMED College of Medicine, RNA, Signal Transduction/physiology, Smad3 Protein/metabolism, Transcription, Transforming Growth Factor beta1/*metabolism, Tumor
Tags: 2002, Animal, Animals, Calcitonin Gene-Related Peptide/biosynthesis, Capsaicin/pharmacology, Cervical Ripening/*metabolism, Cervix Uteri/*innervation/*metabolism, Collins J J, Complementary/metabolism, Department of Anatomy & Neurobiology, Female, Genetic, Immunohistochemistry, Labor, McCarson K E, Messenger/metabolism, NEOMED College of Medicine, Neurokinin-1/biosynthesis, Neurons/metabolism, Neuropeptides/*biosynthesis, Nitric Oxide Synthase/biosynthesis, Obstetric, Papka R E, Peptides, Plasmids/metabolism, Postpartum Period, Pregnancy, Rats, Receptors, RNA, Secretogranin II, Sprague-Dawley, Substance P/biosynthesis, Transcription, Usip S
Tags: 2001, 3T3 Cells, Animals, Carrier Proteins/*biosynthesis/genetics, Heat-Shock Proteins/*biosynthesis/genetics, Herpesvirus 1, Human/isolation & purification/*physiology, Humans, Mao H, Messenger/metabolism, Mice, Molecular Chaperones/*biosynthesis/genetics, Palmer D, RNA, Rosenthal K S, Virus research
The effects of pregnancy and estrogen on the expression of calcitonin gene-related peptide (CGRP) in the uterine cervix, dorsal root ganglia and spinal cord.
Tags: 2003, Animals, Calcitonin Gene-Related Peptide/analysis/biosynthesis/*genetics, Cervix Uteri/*physiology, Collins J, Department of Anatomy & Neurobiology, Estrogens/*physiology, Female, Ganglia, Hargreaves K M, Immunohistochemistry, In Situ Hybridization, Messenger/metabolism, Mowa C N, NEOMED College of Medicine, Papka R E, Peptides, Pregnancy, Radioimmunoassay, Rats, RNA, Spinal Cord/*physiology, Spinal/*physiology, Sprague-Dawley, Storey-Workley M, Usip S
Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis.
Tags: *Phytotherapy, *Punicaceae, 2017, ACLT, Akhtar Nahid, Animal, Animals, Anterior Cruciate Ligament/drug effects/metabolism/pathology, Apoptosis, Ashruf Omer S, Cartilage/cytology/*drug effects/metabolism/pathology, Chondrocytes/drug effects/metabolism/pathology, Collagen Type II/genetics/metabolism, Department of Anatomy & Neurobiology, Dinoprostone/*metabolism, Disease Models, Disease Progression, Female, Fruit, Haqqi Tariq M, Interleukins/metabolism, Joints/cytology/*drug effects/metabolism/pathology, Khan Nazir M, Male, Messenger/metabolism, Metalloproteases/genetics/*metabolism, Mitogen-Activated Protein Kinases/metabolism, MMPs, NEOMED College of Medicine, NF-kappa B/metabolism, Nutrition (Burbank, Los Angeles County, Calif.), Osteoarthritis, Osteoarthritis/*drug therapy/etiology/metabolism/pathology, PGE(2), Plant Extracts/pharmacology/therapeutic use, Pomegranate, Rabbit, Rabbits, RNA, Synovial Fluid/metabolism
Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1.
Tags: 2017, Acetylation/drug effects, Animals, Butyrates/pharmacology, Cell Line, Cell Survival/drug effects, Department of Pharmaceutical Sciences, Dopamine Plasma Membrane Transport Proteins/*metabolism, Dopamine transporter, Dopaminergic Neurons/cytology/drug effects/metabolism, Dose-Response Relationship, Drug, Eid Aseel, Epigenesis, Epigenetics, Genetic, Genetic/drug effects, Green Ashley L, Group A, Guo Grace L, HDAC, Histone deacetylase, Histone Deacetylase Inhibitors/*pharmacology, Histone Deacetylases/metabolism, Histones/*drug effects/metabolism, Homeodomain Proteins/metabolism, Hydroxamic Acids/pharmacology, Member 2/*metabolism, Messenger/metabolism, NEOMED College of Pharmacy, Neuropharmacology, Nuclear Receptor Subfamily 4, Nurr1, Pitx3, Promoter Regions, Rats, Richardson Jason R, RNA, Transcription Factors/metabolism, Valproate, Valproic Acid/*pharmacology, Zarbl Helmut, Zhan Le
Tags: 2017, Animals, BDNF, Brain-Derived Neurotrophic Factor/metabolism, Cerebral Cortex/*drug effects/growth & development/metabolism, Corpus Striatum/*drug effects/growth & development/metabolism, Deltamethrin, Department of Pharmaceutical Sciences, Female, Inbred C57BL, Insecticides/*toxicity, Magby Jason P, Male, Messenger/metabolism, Mice, NEOMED College of Pharmacy, Neurodevelopmental, Neurons/*drug effects/metabolism, Neurotoxicology, Nitriles/*toxicity, Pregnancy, Prenatal Exposure Delayed Effects/*metabolism, Pyrethrins/*toxicity, Pyrethroid, Richardson Jason R, RNA, Sodium channel, Voltage-Gated Sodium Channels/*metabolism
Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.
Tags: 2017, Alam Gelerah, Animals, Astrocytes/immunology/pathology, Beier Eric E, Cell Death/physiology, Corpus Striatum/immunology/pathology, Cytokines/metabolism, Department of Pharmaceutical Sciences, Disease Progression, Dopaminergic Neurons/*immunology/pathology, Edler Melissa, Inbred C57BL, Inflammation/pathology/physiopathology, Lipopolysaccharides/*toxicity, Male, Messenger/metabolism, Mice, Microglia/*immunology/pathology, Neal Matthew, NEOMED College of Pharmacy, Nerve Degeneration/*immunology/pathology, Neurobiology of disease, Neurodegenerative Diseases/immunology/pathology, Neuroimmunomodulation/physiology, Random Allocation, Richardson Jason R, RNA, Time Factors, Wu Long-Jun
A splicing mutation in the cytochrome b5 gene from a patient with congenital methemoglobinemia and pseudohermaphrodism.
Tags: *DNA, *Mutation, 1994, Base Sequence, Cytochromes b5/*genetics, Disorders of Sex Development/*enzymology/genetics, DNA Primers/chemistry, Gene Deletion, Giordano S J, Human genetics, Humans, Kaftory A, Leukocytes/metabolism, Male, Messenger/metabolism, Methemoglobinemia/*congenital/*enzymology, Molecular Sequence Data, Polymerase Chain Reaction, Recombinant, Reticulocytes/metabolism, RNA, Steggles A W
Tags: *Cell Movement, 2016, Arosarena Oneida A, Barr Eric W, Bryant Evan, Carcinoma, Cell Adhesion, Cell Line, Cell Proliferation, Cell Survival, Dela Cadena Raul A, Denny Michael F, Department of Anatomy & Neurobiology, Enzyme Activation, Gene Expression Regulation, Head and Neck Neoplasms/genetics/*metabolism/pathology, Humans, Integrin beta1/metabolism, Journal of cellular physiology, Membrane Glycoproteins/genetics/*metabolism, Messenger/metabolism, Mitogen-Activated Protein Kinases/metabolism, Mouth Neoplasms/genetics/*metabolism/pathology, NEOMED College of Medicine, Neoplasm Invasiveness, Neoplastic, Protein Binding, RNA, RNA Interference, Safadi Fayez F, Signal Transduction, Squamous Cell Carcinoma of Head and Neck, Squamous Cell/genetics/*metabolism/pathology, Thorpe Ryan, Time Factors, Transfection, Tumor
Regulation of cholesterol and bile acid homeostasis by the cholesterol 7alpha-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice.
Tags: 2013, Acetyl Coenzyme A/metabolism, Animal, Animals, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/*metabolism, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Francl Jessica M, Hepatology (Baltimore, Md.), Homeostasis/*physiology, Knockout, Li Tiangang, Lipid Metabolism/physiology, Liver/metabolism, Male, Messenger/metabolism, Mice, MicroRNAs/*metabolism, Models, NEOMED College of Medicine, RNA, Signal Transduction/*physiology, Sterol Regulatory Element Binding Protein 2/*metabolism, Transgenic