Browse Items (21 total)
- Tags: Chemoprevention
Dietary Phytochemicals In The Chemoprevention And Treatment Of Hepatocellular Carcinoma: In Vivo Evidence, Molecular Targets, And Clinical Relevance
Tags: 2012, acid phenethyl ester, altered hepatic foci, Bishayee A, black tea, Carcinoma, Chemoprevention, Current cancer drug targets, Darvesh A S, Department of Pharmaceutical Sciences, Dietary, diethylnitrosamine-induced hepatocarcinogenesis, Hepatocarcinogenesis, Hepatocellular, Implanted, Journal Article or Conference Abstract Publication, Kruse J A, Liver cancer, liver preneoplastic foci, model, multiorgan carcinogenesis model, NEOMED College of Pharmacy, nitrosodiethylamine-induced, Novotny N A, nude-mice, oncology, phenobarbital-induced hepatocarcinogenesis, phytochemicals, Polyphenols, resistant hepatocyte, Thoppil R J, Treatment, Waghray A
Black Currant Phytoconstituents Exert Chemoprevention Of Diethylnitrosamine-initiated Hepatocarcinogenesis By Suppression Of The Inflammatory Response
Tags: 2013, Bhatia D, Biochemistry & Molecular Biology, Bishayee A, cancer-cell proliferation, Chemoprevention, cyclooxygenase-2, cyclooxygenase-2 inhibitors, Darvesh A S, Department of Pharmaceutical Sciences, gamma-glutamyl-transferase, Háznagy-Radnai E, Heat-Shock Proteins, Hepatocarcinogenesis, Hohmann J, human hepatocellular-carcinoma, Inflammation, Journal Article or Conference Abstract Publication, Liver cancer, Mandal A, Meszaros J G, Molecular carcinogenesis, molecular chaperones, NEOMED College of Pharmacy, nf-kappa-b, nuclear factor-B, Ohanyan V, oncology, ribes-nigrum, Signaling, Thoppil R J, united-states
Pomegranate Phytoconstituents Blunt The Inflammatory Cascade In A Chemically Induced Rodent Model Of Hepatocellular Carcinogenesis
Tags: 2013, Bhatia D, Biochemistry & Molecular Biology, Bishayee A, cancer chemoprevention, Chemoprevention, cyclooxygenase-2, Darvesh A S, Department of Pharmaceutical Sciences, factor-kappa-b, gene-expression, Heat-Shock Proteins, Hepatocarcinogenesis, human-disease, Inflammation, inhibitors, Journal Article or Conference Abstract Publication, Journal of Nutritional Biochemistry, Meszaros J G, molecular chaperones, NEOMED College of Pharmacy, nitric-oxide synthase, Nuclear factor-kappaB, Nutrition & Dietetics, Ohanyan V, Oxidative Stress, Pomegranate, punica-granatum l., Thoppil R J
Chemopreventive Effect Of A Novel Oleanane Triterpenoid In A Chemically Induced Rodent Model Of Breast Cancer
Tags: 2013, amooranin, Apoptosis, Bhatia D, Bishayee A, breast cancer, Carcinogenesis, carcinoma cell-lines, cddo-methyl ester, Cell, Chemoprevention, Darvesh A S, Department of Pharmaceutical Sciences, DMBA, growth arrest, International Journal of Cancer, Journal Article or Conference Abstract Publication, Mammary, Mandal A, Mice, NEOMED College of Pharmacy, oleanane triterpenoid, oncology, Prevention, proliferation, rat, Thoppil R J, tumor-growth
Update On Prostate Cancer Chemoprevention
Tags: 2006, 5-alpha-reductase inhibitors, Antigen, beta-carotene, Chemoprevention, Clinical Trial, Department of Internal Medicine, dutasteride, finasteride, Frazee L A, Lowe J F, men, NEOMED College of Medicine, nonsteroidal antiinflammatory drugs, over-expression, PCPT, Pharmacology & Pharmacy, Pharmacotherapy, Prevention, Prostate cancer, REDUCE trial, Risk, SELECT, selenium level
Dietary Phytochemicals In The Chemoprevention And Treatment Of Hepatocellular Carcinoma: In Vivo Evidence, Molecular Targets, And Clinical Relevance
Tags: 2012, acid phenethyl ester, altered hepatic foci, Bishayee A, black tea, Carcinoma, Chemoprevention, Current cancer drug targets, Darvesh A S, Department of Pharmaceutical Sciences, Dietary, diethylnitrosamine-induced hepatocarcinogenesis, Hepatocarcinogenesis, Hepatocellular, Implanted, Kruse J A, Liver cancer, liver preneoplastic foci, model, multiorgan carcinogenesis model, NEOMED College of Pharmacy, nitrosodiethylamine-induced, Novotny N A, nude-mice, oncology, phenobarbital-induced hepatocarcinogenesis, phytochemicals, Polyphenols, resistant hepatocyte, Thoppil R J, Treatment, Waghray A
Black Currant Phytoconstituents Exert Chemoprevention Of Diethylnitrosamine-initiated Hepatocarcinogenesis By Suppression Of The Inflammatory Response
Tags: 2013, Bhatia D, Biochemistry & Molecular Biology, Bishayee A, cancer-cell proliferation, Chemoprevention, cyclooxygenase-2, cyclooxygenase-2 inhibitors, Darvesh A S, Department of Pharmaceutical Sciences, gamma-glutamyl-transferase, Háznagy-Radnai E, Heat-Shock Proteins, Hepatocarcinogenesis, Hohmann J, human hepatocellular-carcinoma, Inflammation, Liver cancer, Mandal A, Meszaros J G, Molecular carcinogenesis, molecular chaperones, NEOMED College of Pharmacy, nf-kappa-b, nuclear factor-B, Ohanyan V, oncology, ribes-nigrum, Signaling, Thoppil R J, united-states
Pomegranate Phytoconstituents Blunt The Inflammatory Cascade In A Chemically Induced Rodent Model Of Hepatocellular Carcinogenesis
Tags: 2013, Bhatia D, Biochemistry & Molecular Biology, Bishayee A, cancer chemoprevention, Chemoprevention, cyclooxygenase-2, Darvesh A S, Department of Pharmaceutical Sciences, factor-kappa-b, gene-expression, Heat-Shock Proteins, Hepatocarcinogenesis, human-disease, Inflammation, inhibitors, Journal of Nutritional Biochemistry, Meszaros J G, molecular chaperones, NEOMED College of Pharmacy, nitric-oxide synthase, Nuclear factor-kappaB, Nutrition & Dietetics, Ohanyan V, Oxidative Stress, Pomegranate, punica-granatum l., Thoppil R J
Chemopreventive Effect Of A Novel Oleanane Triterpenoid In A Chemically Induced Rodent Model Of Breast Cancer
Tags: 2013, amooranin, Apoptosis, Bhatia D, Bishayee A, breast cancer, Carcinogenesis, carcinoma cell-lines, cddo-methyl ester, Cell, Chemoprevention, Darvesh A S, Department of Pharmaceutical Sciences, DMBA, growth arrest, International Journal of Cancer, Mammary, Mandal A, Mice, NEOMED College of Pharmacy, oleanane triterpenoid, oncology, Prevention, proliferation, rat, Thoppil R J, tumor-growth
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Antineoplastic Agents – Therapeutic Use, Apoptosis – Drug Effects, Biochemical Phenomena, Bishayee A, Cell Physiology – Drug Effects, Chemoprevention, Darvesh A S, Department of Pharmaceutical Sciences, Folkesson H G, Háznagy-Radnai E, Hohmann J, Journal of Nutritional Biochemistry, Liver – Pathology, Liver Neoplasms – Chemically Induced, Liver Neoplasms – Metabolism, Liver Neoplasms – Pathology, Liver Neoplasms – Prevention and Control, Male, Mbimba T, NEOMED College of Pharmacy, Nitrosamines, Phenobarbital, Plant Extracts – Therapeutic Use, Plants, Preventive Cardiovascular Nurses Association, Proteins – Metabolism, Rats, Sipos P, Thoppil R J
Terpenoids as potential chemopreventive and therapeutic agents in liver cancer.
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-kappaB and Nrf2 Signaling Pathways.
Tags: 10-Dimethyl-1, 2-benzanthracene/toxicity, 2017, 9, Animal Studies, Animals, Anti-Inflammatory Agents/*pharmacology, anti-inflammatory effects, Anticarcinogenic Agents/pharmacology, Apoptosis/drug effects, Bhatia Deepak, Bishayee Anupam, Breast Neoplasms, breast tumor, Cell Transformation, Chemoprevention, COX-2, Cyclooxygenase 2/genetics/metabolism, DMBA, Dose-Response Relationship, Drug, Experimental/*prevention & control, Female, Gene Expression Regulation, HSP90, HSP90 Heat-Shock Proteins/genetics/metabolism, I-kappa B Kinase/genetics/metabolism, Inflammation Mediators, Mammary Neoplasms, Mandal Animesh, Neoplasms – Prevention and Control, Neoplastic, Neoplastic/drug effects, NF-E2-Related Factor 2/genetics/*metabolism, NF-kappa B/genetics/*metabolism, NF-kappaB, Nrf2, Nutrients, Physical Education and Training, Plant Preparations/*pharmacology, Pomegranate, Punica granatum, Punicaceae/*chemistry, Rats, Signal Transduction
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.
Tags: 2011, Ahmed Shamima, Animals, Anticarcinogenic Agents/chemistry/*therapeutic use, Antineoplastic Agents, Bishayee Anupam, Brankov Nikoleta, Breast Neoplasms/*drug therapy/*prevention & control, Chemoprevention, Frontiers in bioscience (Landmark edition), Glycosides/therapeutic use, Humans, Mice, Oleanolic Acid/analogs & derivatives/therapeutic use, Perloff Marjorie, Phytogenic/therapeutic use, Triterpenes/*therapeutic use
Potential Benefits of Edible Berries in the Management of Aerodigestive and Gastrointestinal Tract Cancers: Preclinical and Clinical Evidence.
Tags: 2016, aerodigestive and gastrointestinal tract, Animal, Animal Studies, Animals, Anthocyanins/analysis/pharmacology, Anticarcinogenic Agents/*analysis/pharmacology, Antineoplastic Agents – Analysis, Antineoplastic Agents – Pharmacodynamics, Benzopyrans – Analysis, Benzopyrans – Pharmacodynamics, Berry, Biological, Bishayee Anupam, Cancer, Chemoprevention, Clinical Trials, Clinical Trials as Topic, Critical reviews in food science and nutrition, Digestion – Drug Effects, Digestion/drug effects, Disease Models, Do Chau, Ellagic Acid/analysis/pharmacology, Fruit, Fruit/*chemistry, Gastrointestinal Neoplasms – Prevention and Control, Gastrointestinal Neoplasms/*prevention & control, Haskell Yennie, Human, Humans, Models, Mohandas Nima, Phytochemicals – Analysis, Phytochemicals – Pharmacodynamics, Phytochemicals/analysis/pharmacology, Plant Extracts – Analysis, Plant Extracts – Pharmacodynamics, Plant Extracts/*analysis/pharmacology, Polyphenols – Analysis, Polyphenols – Pharmacodynamics, Polyphenols/analysis/pharmacology, Sethi Gautam, Siveen Kodappully Sivaraman, Stoner Gary D, Treatment
Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.
Tags: *Anticarcinogenic Agents, 2013, Animal, Animals, Anti-Inflammatory Agents, Antioxidants, Biological Availability, Biological Markers, Bishayee Anupam, Carcinoma, Catechin/administration & dosage/analogs & derivatives, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Disease Models, Hepatocellular – Physiopathology, Hepatocellular – Prevention and Control, Hepatocellular – Therapy, Human, Humans, In Vitro Studies, In Vivo Studies, Liver Neoplasms/*drug therapy/*prevention & control, Mice, NEOMED College of Pharmacy, Neoplasms – Prevention and Control, nutrition, Nutrition and cancer, Outcomes (Health Care), Phenols – Therapeutic Use, Polyphenols/*administration & dosage/pharmacology, Tea – Therapeutic Use, Tea/*chemistry, Xenograft Model Antitumor Assays
Trianthema portulacastrum Linn. exerts chemoprevention of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats.
Tags: *Dietary Supplements, *Mammary Neoplasms, 10-Dimethyl-1, 2-benzanthracene/*toxicity, 2014, 9, Aizoaceae/*chemistry, Animals, Apoptosis, Bax, Bcl-2, bcl-2-Associated X Protein/metabolism, beta-catenin, Bishayee Anupam, breast cancer, Carcinogens/*toxicity, Cell Proliferation, Cell Proliferation/drug effects, Chemoprevention, Cyclin D1, DMBA, Experimental/chemically induced/metabolism/pathology/prevention & control, Humans, Male, Mandal Animesh, Medicinal/*chemistry, Mutation research, Phytotherapy/*methods, Plants, Proliferating Cell Nuclear Antigen/metabolism, Rats, Sprague-Dawley, Trianthema portulacastrum, Up-Regulation/drug effects, Wnt Signaling Pathway/drug effects
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.
Tags: 2011, Animals, Anthocyanins/*therapeutic use, Anticarcinogenic Agents/therapeutic use, Apoptosis/drug effects, bcl-2-Associated X Protein/metabolism, Bishayee Anupam, Cell Proliferation/drug effects, Chemoprevention, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Down-Regulation, Experimental/metabolism/pathology, Folkesson Hans G, Haznagy-Radnai Erzsebet, Hohmann Judit, Liver Neoplasms, Liver Neoplasms/chemically induced/*prevention & control, Liver/pathology, Male, Mbimba Thomas, NEOMED College of Pharmacy, Phenobarbital, Plant Extracts/*therapeutic use, Proliferating Cell Nuclear Antigen/metabolism, Proto-Oncogene Proteins c-bcl-2/metabolism, Rats, Ribes/chemistry, Sipos Peter, Sprague-Dawley, The Journal of nutritional biochemistry, Thoppil Roslin J, Up-Regulation
Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives.
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.
Tags: 2010, Animals, Anticarcinogenic Agents/*therapeutic use, Barnes Kendra F, Bhatia Deepak, Bishayee Anupam, Chatterjee Malay, Chemoprevention, Cyclooxygenase 2/immunology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Diethylnitrosamine, Female, HSP70 Heat-Shock Proteins/immunology, Humans, Inflammation/prevention & control, Liver Neoplasms/chemically induced/*immunology/*prevention & control, Liver/drug effects/pathology, Mbimba Thomas, NEOMED College of Pharmacy, NF-kappa B/immunology, Pharmaceutical research, Rats, Resveratrol, Sprague-Dawley, Stilbenes/*therapeutic use, Waghray Abhijeet
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.
Tags: *Chemoprevention, 2011, Analysis of Variance, Animal, Animal Studies, Animal/drug effects, Animals, Antioxidants, Behavior, Bishayee Anupam, Blotting, Booth Tristan D, Carcinoma, Cardiotoxicity, Cardiotoxins/*toxicity, Chemoprevention, Data Analysis Software, Department of Integrative Medical Sciences, Descriptive Statistics, Disease Models, Doppler, Dose-Response Relationship, Drug, Echocardiography, Feeding Behavior/drug effects, Female, Fisher's Exact Test, Funding Source, Heart – Drug Effects, Heart/drug effects/physiopathology, Hepatocellular – Prevention and Control, Hepatocellular/*drug therapy/pathology/physiopathology, Hepatocytes/drug effects/pathology, Hodnichak Cheryl M, Humans, Investigational new drugs, Liver Neoplasms/*drug therapy/pathology/physiopathology, Liver/drug effects/pathology/physiopathology, Luther Daniel J, Meszaros J Gary, NEOMED College of Medicine, Ohanyan Vahagn, Polyphenols – Therapeutic Use, Rats, Resveratrol, Shamhart Patricia E, Sisakian Hamayak, Sprague-Dawley, Stilbenes/*therapeutic use, Systole/drug effects, Western