Browse Items · NEOMED Bibliography Database

Carboplatin and paclitaxel for the treatment of advanced or recurrent endometrial cancer.

OBJECTIVE: The purpose of this study was to determine the activity and toxicity of carboplatin and paclitaxel (taxol) in the treatment of advanced or recurrent endometrial cancer. STUDY DESIGN: This was a retrospective review of 18 consecutive…

Improving Outcomes in Early-Stage Breast Cancer.

Incorporating the Oncotype DX breast cancer assay into community practice: an expert Q&A and case study sampling.

Advances in breast cancer research have confirmed that this malignancy is not a single disease, but rather a collection of genetically distinct diseases with different treatment requirements. In recent years, several studies have confirmed the…

Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cells.

Dietary antioxidants, such as anthocyanins, are helpful in the prevention and control of various diseases by counteracting the imbalance of oxidative and antioxidative factors in the living systems. Black currant (Ribes nigrum L., Grossulariaceae) is…

A case of Riedel's thyroiditis treated with tamoxifen: another successful outcome.

OBJECTIVE: To report a case of Riedel's thyroiditis, which was successfully treated with tamoxifen. METHODS: We present the clinical, laboratory, and imaging findings and describe the clinical course of a patient with Riedel's thyroiditis. RESULTS: A…

Tags: 2004, Adult, Antineoplastic Agents, Department of Family & Community Medicine, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, Female, Goiter/*drug therapy/pathology, Hormonal/*administration & dosage, Humans, Hypothyroidism/drug therapy/pathology, Jung Yiechul J, Magnetic Resonance Imaging, Muehlenbein Stephen J, NEOMED College of Medicine, Rhodes Ronald, Rich Frank A, Schaub Carl R, Tamoxifen/*administration & dosage, Thyroiditis/*drug therapy/pathology

Present state and future prospects: a review of cooperative groups' adjuvant and neoadjuvant trials in breast cancer.

In patients with operable breast cancer, adjuvant hormonal therapy and adjuvant chemotherapy result in significant and long-term reductions in the rates of disease recurrence and death. These reductions are evident in both patients with node-negative…

Tags: 2001, Adjuvant, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols/*therapeutic use, Breast Neoplasms/*drug therapy/surgery, Chemotherapy, Clinical breast cancer, Clinical Trials as Topic, Decision Making, Diphosphonates/therapeutic use, Female, Hormonal/*therapeutic use, Humans, Mamounas E P, Neoadjuvant Therapy, Ovary/drug effects/physiology, Prognosis, Tamoxifen/administration & dosage, Taxoids/therapeutic use

Antitumor activities of extracts from selected desert plants against HepG2 human hepatocellular carcinoma cells.

CONTEXT: Phytochemicals are produced by desert plants to protect themselves against stressful environments. They have been shown to be useful in preventing and fighting adverse pathophysiological conditions and complex diseases, including cancer.…

Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers.

Paclitaxel is not effective for treatment of brain cancers because it cannot cross the blood-brain barrier (BBB) due to efflux by P-glycoprotein (P-gp). In this work, glutathione-coated poly-(lactide-co-glycolide) (PLGA) nanoparticles (NPs) of…

Tags: *Drug Delivery Systems, 2011, Adenosine Triphosphatases/metabolism, Animals, Antineoplastic Agents, ATP Binding Cassette Transporter, Blood-Brain Barrier/metabolism, Brain Neoplasms/drug therapy, Bui Thong, Cell Death/drug effects, Cell Line, Coumarins/administration & dosage/pharmacokinetics, Delayed-Action Preparations, Geldenhuys Werner, Glioma/drug therapy/pathology, Glutathione/*chemistry, Harrison Kimberly, Humans, Inbred C57BL, Journal of drug targeting, Male, Mbimba Thomas, Member 1/metabolism, Mice, Microtubules/metabolism, Nanoparticles, Paclitaxel/administration & dosage/*pharmacokinetics/pharmacology, Particle Size, Permeability, Phytogenic/administration & dosage/*pharmacokinetics/pharmacology, Rats, Subfamily B, Sutariya Vijaykumar, Thiazoles/administration & dosage/pharmacokinetics, Tubulin/metabolism, Tumor

Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.

Breast cancer remains a major cause of death in the United States as well as the rest of the world. In view of the limited treatment options for patients with advanced breast cancer, preventive and novel therapeutic approaches play an important role…

Tags: 2011, Ahmed Shamima, Animals, Anticarcinogenic Agents/chemistry/*therapeutic use, Antineoplastic Agents, Bishayee Anupam, Brankov Nikoleta, Breast Neoplasms/*drug therapy/*prevention & control, Chemoprevention, Frontiers in bioscience (Landmark edition), Glycosides/therapeutic use, Humans, Mice, Oleanolic Acid/analogs & derivatives/therapeutic use, Perloff Marjorie, Phytogenic/therapeutic use, Triterpenes/*therapeutic use

Curcumin and liver cancer: a review.

Primary liver cancer, also known as hepatocellular carcinoma (HCC), is one of the most lethal cancers having worldwide prevalence. Although most HCC cases are reported in the developing countries of Asia and Africa, there has been an alarming…

Tags: 2012, Aggarwal Bharat B, Animals, Anti-Inflammatory Agents/therapeutic use, Anticarcinogenic Agents/*therapeutic use, Antineoplastic Agents, Antioxidants/therapeutic use, Bishayee Anupam, Carcinoma, Curcumin/*therapeutic use, Current pharmaceutical biotechnology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Hepatocellular/*drug therapy/prevention & control, Humans, Liver Neoplasms/*drug therapy/prevention & control, NEOMED College of Pharmacy, Phytogenic/*therapeutic use

Can we approach zero relapse in breast cancer?

Adjuvant hormonal therapy and adjuvant chemotherapy have contributed significantly to the falling rates of breast cancer mortality. The introduction of taxanes and aromatase inhibitors in the adjuvant setting represents recent important improvements.…

Tags: 2005, Adjuvant, Antineoplastic Agents, Aromatase Inhibitors/therapeutic use, Breast Neoplasms/mortality/pathology/*prevention & control/*therapy, Chemotherapy, Disease-Free Survival, Female, Gene Expression Profiling, Hormonal/*therapeutic use, Humans, Lymph Nodes/pathology, Mamounas Eleftherios P, Neoadjuvant Therapy, Prognosis, Recurrence, The oncologist

The health benefits of blackcurrants.

The blackcurrant (Ribes nigrum L., Grossulariceae), a small, perennial shrub native to central Europe and northern Asia, is cultivated throughout the world, including the United States. In addition to its anecdotal use in traditional herbal medicine,…

Can tamoxifen cause a significant mammographic density change in breast parenchyma?

To evaluate tamoxifen-induced glandular tissue density changes in women who are on an adjuvant tamoxifen therapy. We examined serial mammograms of 27 women (average age 67) who had surgery for unilateral breast carcinoma and were on tamoxifen for 5…

Tags: 2001, Aged, Antineoplastic Agents, Breast Neoplasms/*diagnostic imaging/*prevention & control/surgery, Breast/anatomy & histology/*drug effects, Clinical imaging, Computer-Assisted, Female, Goyal M, Hormonal/*pharmacology, Humans, Image Processing, Konez O, Mammography, Reaven R E, Tamoxifen/*pharmacology

BCNU-induced gR2 defect mediates S-glutathionylation of Complex I and respiratory uncoupling in myocardium.

A deficiency of mitochondrial glutathione reductase (or GR2) is capable of adversely affecting the reduction of GSSG and increasing mitochondrial oxidative stress. BCNU [1,3-bis (2-chloroethyl)-1-nitrosourea] is an anticancer agent and known…

Tags: 2014, Alkylating/*adverse effects/pharmacology, Animals, Antineoplastic Agents, Biochemical pharmacology, Cardiotoxins/adverse effects/pharmacology, Carmustine/*adverse effects/pharmacology, Cattle, Cell Line, Chen Chwen-Lih, Chen Yeong-Renn, Complex I, Department of Integrative Medical Sciences, Electron Transport Complex I/chemistry/*metabolism, Fatty Acids, Glutathione reductase, Glutathione Reductase/*antagonists & inhibitors/metabolism, Glutathione/*metabolism, Guarini Giacinta, Heart Ventricles/drug effects/metabolism/physiopathology, Heart/*drug effects/metabolism, Ion Channels/metabolism, Kang Patrick T, Left/*chemically induced/metabolism/physiopathology, Male, Mice, Mitochondria, Mitochondrial Proteins/metabolism, NEOMED College of Medicine, Nonesterified/metabolism, Oxidative Stress, Oxidative Stress/drug effects, Post-Translational/drug effects, Protein Processing, Rats, Ren Pei, S-Glutathionylation, Sprague-Dawley, Superoxide Dismutase/genetics/metabolism, Systolic dysfunction, Transgenic, Uncoupling Protein 3, Ventricular Dysfunction

Carboplatin and paclitaxel for the treatment of advanced or recurrent endometrial cancer.

OBJECTIVE: The purpose of this study was to determine the activity and toxicity of carboplatin and paclitaxel (taxol) in the treatment of advanced or recurrent endometrial cancer. STUDY DESIGN: This was a retrospective review of 18 consecutive…

Browse Items (15 total)