Browse Items (5 total)
- Tags: ATP Binding Cassette Transporter
Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.
Tags: 2003, ATP Binding Cassette Transporter, ATP-Binding Cassette Transporters/*genetics, Biochemical and biophysical research communications, Cell Line, Chenodeoxycholic Acid/antagonists & inhibitors, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*genetics, Cytoplasmic and Nuclear/*metabolism, Department of Integrative Medical Sciences, DNA-Binding Proteins/*antagonists & inhibitors/metabolism, Dose-Response Relationship, Drug, Gene Expression Regulation/drug effects, Humans, Member 11, NEOMED College of Medicine, Owsley Erika, Pregnane X Receptor, Pregnenediones/*pharmacology, Receptors, Steroid/*metabolism, Subfamily B, Transcription Factors/*antagonists & inhibitors/metabolism, Transcriptional Activation/drug effects
Tags: *Drug Delivery Systems, 2011, Adenosine Triphosphatases/metabolism, Animals, Antineoplastic Agents, ATP Binding Cassette Transporter, Blood-Brain Barrier/metabolism, Brain Neoplasms/drug therapy, Bui Thong, Cell Death/drug effects, Cell Line, Coumarins/administration & dosage/pharmacokinetics, Delayed-Action Preparations, Geldenhuys Werner, Glioma/drug therapy/pathology, Glutathione/*chemistry, Harrison Kimberly, Humans, Inbred C57BL, Journal of drug targeting, Male, Mbimba Thomas, Member 1/metabolism, Mice, Microtubules/metabolism, Nanoparticles, Paclitaxel/administration & dosage/*pharmacokinetics/pharmacology, Particle Size, Permeability, Phytogenic/administration & dosage/*pharmacokinetics/pharmacology, Rats, Subfamily B, Sutariya Vijaykumar, Thiazoles/administration & dosage/pharmacokinetics, Tubulin/metabolism, Tumor
Tags: *Lipid Metabolism, 2007, ATP Binding Cassette Transporter, ATP Binding Cassette Transporter 1, ATP-Binding Cassette Transporters/genetics, Base Sequence, Cell Line, Chen Wenling, Chiang John Y L, Cholestanetriol 26-Monooxygenase/*metabolism, Cholesterol, Cholesterol/*metabolism, Department of Integrative Medical Sciences, Fluorinated, Genes, Genetic/drug effects, Genetic/genetics, HDL/metabolism, Hepatocytes/drug effects/enzymology/metabolism, Humans, Hydrocarbons, Hydroxycholesterols/metabolism/pharmacology, Intestinal Mucosa/metabolism, Intestines/cytology/drug effects/enzymology, Journal of lipid research, Li Tiangang, Member 1, Messenger/genetics/metabolism, Molecular Sequence Data, NEOMED College of Medicine, Pregnane X Receptor, Promoter Regions, Receptors, Reporter, Response Elements/genetics, Rifampin/pharmacology, RNA, Steroid/*metabolism, Subfamily G, Sulfonamides/pharmacology, Transcription, Up-Regulation/drug effects
Effects of gelucire content on stability, macrophage interaction and blood circulation of nanoparticles engineered from nanoemulsions.
Tags: 2012, Animals, ATP Binding Cassette Transporter, Calorimetry, Colloids and surfaces. B, Biointerfaces, Department of Pharmaceutical Sciences, Differential Scanning, Drug Carriers/*chemical synthesis/pharmacokinetics, Drug Stability, Emulsions/chemistry, Fatty Alcohols/*chemistry, Fourier Transform Infrared, Geldenhuys Werner J, Humans, Inbred BALB C, Macrophages/*drug effects/metabolism, Member 1/metabolism, Mice, Nanoparticles/*chemistry/ultrastructure, NEOMED College of Pharmacy, Oils/chemistry, Oyewumi Moses O, Paclitaxel/pharmacokinetics, Particle Size, Polyethylene Glycols/*chemistry, Reactive Oxygen Species/metabolism, Rhodamine 123/metabolism, Spectroscopy, Subfamily B, Water/chemistry, Wehrung Daniel
Overexpression of cholesterol 7alpha-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis.
Tags: 2011, Animals, ATP Binding Cassette Transporter, ATP-Binding Cassette Transporters/metabolism, Bile Acids and Salts/*metabolism, Boehme Shannon, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*biosynthesis, Cholesterol/*metabolism, Cytoplasmic and Nuclear/agonists, Department of Integrative Medical Sciences, Ellis Ewa, Guo Grace, Hepatocytes/drug effects, Hepatology (Baltimore, Md.), Homeostasis, Humans, Isoxazoles/pharmacology, Knockout, Kong Bo, Li Tiangang, Lipoproteins/metabolism, Liver/*metabolism, Matozel Michelle, Member 5, Member 8, Mice, NEOMED College of Medicine, Nilsson Lisa-Mari, Receptors, Subfamily G