A case of Riedel's thyroiditis treated with tamoxifen: another successful outcome.

Title

A case of Riedel's thyroiditis treated with tamoxifen: another successful outcome.

Creator

Jung Yiechul J; Schaub Carl R; Rhodes Ronald; Rich Frank A; Muehlenbein Stephen J

Publisher

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Date

2004
2004-12

Description

OBJECTIVE: To report a case of Riedel's thyroiditis, which was successfully treated with tamoxifen. METHODS: We present the clinical, laboratory, and imaging findings and describe the clinical course of a patient with Riedel's thyroiditis. RESULTS: A 40-year-old woman presented with hypothyroidism and a large goiter, which was unresponsive to hormone replacement therapy. Magnetic resonance imaging confirmed the presence of an enlarged thyroid gland, more pronounced on the right than on the left. The patient had progressive discomfort attributable to compressive symptoms in the neck. Surgical exploration of the neck disclosed a hard, immobile thyroid mass, which could not be resected because of adherence to surrounding structures. Biopsy of the thyroid and of the muscles of the neck revealed Riedel's thyroiditis. Treatment with tamoxifen, in a dosage of 20 mg twice a day for more than 1(1/2) years, completely resolved the neck mass (substantiated by follow-up magnetic resonance imaging) and relieved the signs and symptoms of compression of the neck. CONCLUSION: Tamoxifen treatment is effective in resolving the mass and compression in Riedel's thyroiditis.

Subject

Adult; Female; Humans; Magnetic Resonance Imaging; Goiter/*drug therapy/pathology; Hypothyroidism/drug therapy/pathology; Tamoxifen/*administration & dosage; Thyroiditis/*drug therapy/pathology; Antineoplastic Agents; Hormonal/*administration & dosage

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

483–486

Issue

6

Volume

10

Citation

Jung Yiechul J; Schaub Carl R; Rhodes Ronald; Rich Frank A; Muehlenbein Stephen J, “A case of Riedel's thyroiditis treated with tamoxifen: another successful outcome.,” NEOMED Bibliography Database, accessed September 28, 2022, https://neomed.omeka.net/items/show/5226.

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