Browse Items · NEOMED Bibliography Database

Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.

The process of wound repair requires the coordinated participation of multiple types of cells, which are sequentially recruited during the healing process. In response to tissue injury, both macrophages and mesenchymal stem cells (MSCs) are recruited…

Common fungal infections of the feet in patients with diabetes mellitus.

Superficial fungal infections of the foot (tinea pedis and onychomycosis) are common among elderly patients. Although most authorities believe that patients with diabetes mellitus have an increased predisposition to dermatophytic infections, some…

Inhaled corticosteroid use in asthmatic children receiving Ohio Medicaid: trend analysis, 1997-2001.

BACKGROUND: In 1997, national guidelines emphasized that inhaled corticosteroids (ICSs) are key therapy for individuals with all classes of persistent asthma, including children. OBJECTIVE: To examine the effect of these guidelines via time-trend…

Tags: 2008, Administration, Adolescence, Adrenal Cortex Hormones – Administration and Dosage, Adrenal Cortex Hormones – Therapeutic Use, Ambulatory Care – Statistics and Numerical Data, Annals of Allergy, Asthma & Immunology, Asthma – Diagnosis, Asthma – Drug Therapy, Asthma – Ethnology, Bean JA, Blacks – Statistics and Numerical Data, Child, Cross Sectional Studies, Drug Utilization – Statistics and Numerical Data, Drug Utilization – Trends, Emergency Service – Statistics and Numerical Data, Female, Heaton PC, Hospitalization – Statistics and Numerical Data, Human, Infant, Inhalation, Male, Medicaid – Statistics and Numerical Data, Moomaw CJ, Newborn, Ohio, Preschool, Regression, Retrospective Design, Ruddy RM, Sex Factors, Stevenson MD, United States, Whites – Statistics and Numerical Data

Editorial comment.

Tags: 2010, Administration, Bladder, Bologna R, Botulinum Toxins – Administration and Dosage, Child, Intravesical, Neurogenic – Drug Therapy, Neurogenic – Etiology, Neuromuscular Agents – Administration and Dosage, Spina Bifida – Complications, Urology

Stability of extemporaneously prepared oxandrolone oral suspensions.

Purpose. The stability of extemporaneously prepared oxandrolone oral suspensions was studied. Methods. Oxandrolone oral suspension (1 mg/mL) was prepared using oxandrolone tablets, Ora-Plus, and either Ora-Sweet or Ora-Sweet SF. Three identical…

Tags: 2011, Acid-Base Equilibrium, Administration, American Journal of Health-System Pharmacy, Androgens – Administration and Dosage, Cober Mary Petrea, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Drug Compounding, Hawkins Katherine A, Human, Johnson Cary E, Julian Justin D, NEOMED College of Pharmacy, Oral, Suspensions, Weight Gain – Chemically Induced

Stability of an extemporaneous alcohol-free melatonin suspension.

Purpose. The stability of alcohol-free oral suspensions of melatonin 1 mg/mL, extemporaneously prepared from two commercially available melatonin tablet products, was studied. Methods. Four 1-mg/mL melatonin suspensions were prepared. Formulations A…

Tags: 2011, Administration, American Journal of Health-System Pharmacy, Cober Mary Petrea, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Drug Compounding, Drug Stability, Johnson Cary E, Melatonin, NEOMED College of Pharmacy, Oral, Rouse Emily, Suspensions, Taste, Thome Tennille

Overview of the treatment of acne vulgaris with topical retinoids.

Acne vulgaris is a common skin disease that is most effectively treated with a combination of topical products and, in some cases, systemic antibiotics. While it is important to treat papules, pustules, nodules, and cysts with topical or systemic…

Tags: 2011, Acne Vulgaris – Drug Therapy, Acne Vulgaris – Physiopathology, Administration, Brodell R T, Hsu P, Human, Litman GI, Postgraduate medicine, Primary Health Care, Retinoids – Administration and Dosage, Retinoids – Adverse Effects, Retinoids – Therapeutic Use, Severity of Illness Indices, Transcutaneous

Assessment of the Clinical Use of Intravenous and Oral N-Acetylcysteine in the Treatment of Acute Acetaminophen Poisoning in Children: A Retrospective Review.

Abstract: Background: N-acetylcysteine (NAC) is the most effective therapy for acetaminophen (APAP) toxicity and is currently available for oral and intravenous (IV) administration. Although both routes are effective, use of the IV formulation has…

Tags: 2011, Acetaminophen – Adverse Effects, Acetylcysteine – Therapeutic Use, Administration, Blackford Martha G, Clinical Therapeutics, Cost Benefit Analysis, Descriptive Statistics, Felter Thomas, Gothard M David, Intravenous, Medical Records, Oral, Overdose – Drug Therapy, Patient Selection, Poisoning – Drug Therapy, Reed Michael D, Retrospective Design, United States

Managing psoriasis: What's best for your patient?

Tags: 2012, Administration, Adrenal Cortex Hormones – Therapeutic Use, Antiinflammatory Agents – Therapeutic Use, Combined Modality Therapy, Dermatologic Agents – Therapeutic Use, Immunosuppressive Agents – Therapeutic Use, Journal of Family Practice, Male, Mehregan DA, Middle Age, Patient Compliance, Photochemotherapy, Psoriasis – Drug Therapy, Psoriasis – Radiotherapy, Psoriasis – Therapy, Transcutaneous, Uhlenhake EE, Ultraviolet Therapy

Antibiotics for Acute Appendicitis.

The article reports that patients with uncomplicated acute appendicitis can fair well without surgery as compared to clinical trial patients who underwent surgery, and states that patients had lower risk of complications during the one-year follow-up…

Fecal Transplant vs. Oral Vancomycin Taper for Recurrent Clostridium difficile Infection.

In a small randomized, controlled trial that compared fecal microbiota transplant (FMT) administered by enema to a six-week oral vancomycin taper, FMT was not more effective for patients with recurrent Clostridium difficile infection.

Early Uncomplicated Appendicitis-Who Can We Treat Nonoperatively?

This study evaluated nonoperative treatment for mild appendicitis and reviewed selection criteria to be used in introducing this option into clinical practice. A retrospective review of 73 consecutive cases of appendicitis treated by a single surgeon…

Pruritic rash.

Managing psoriasis: what's best for your patient?

Whether the symptoms are mild, moderate, or severe, the optimal treatment plan is the one the patient is most likely to follow.

The effects of intranasal infusion of

Male C57/B1 mice received bilateral intranasal infusions of saline, MPTP or an intraperitoneal injection of MPTP. Infusions were performed using a peristaltic pump at a setting of 100 microliters/min. The MPTP, diluted in saline at concentrations of…

Overview of the treatment of acne vulgaris with topical retinoids.

Acne vulgaris is a common skin disease that is most effectively treated with a combination of topical products and, in some cases, systemic antibiotics. While it is important to treat papules, pustules, nodules, and cysts with topical or systemic…

Tags: 2011, Acne Vulgaris/*drug therapy/physiopathology, Administration, Brodell Robert T, Cutaneous, Hsu Peter, Humans, Litman George I, Postgraduate medicine, Primary Health Care, Retinoids/administration & dosage/adverse effects/*therapeutic use, Severity of Illness Index

Uncovering tinea incognito. Topical corticosteroids can mask typical features of ringworm.

Underlying causes of erythema nodosum. Lesions may provide clue to systemic disease.

Tags: *Erythema Nodosum/diagnosis/drug therapy/etiology, 2000, Administration, Adult, Anti-Inflammatory Agents/therapeutic use, Brodell R T, Clobetasol/*analogs & derivatives/therapeutic use, Contraceptives, Female, Glucocorticoids, Humans, Mehrabi D, Oral/adverse effects, Postgraduate medicine, Pregnancy, Pregnancy Complications, Topical

Topical corticosteroid-induced acne. Three treatment strategies to break the 'addiction' cycle.

Crusted (Norwegian) scabies. A simple office test demystifies the 'great imitator'.

Over diagnosis of chronic obstructive pulmonary disease in an underserved patient population.

INTRODUCTION: While cross-national studies have documented rates of chronic obstructive pulmonary disease (COPD) misdiagnosis among patients in primary care, US studies are scarce. Studies investigating diagnosis among uninsured patients are lacking.…

Tags: *Diagnostic Errors, *Medically Underserved Area, *Spirometry, *Vulnerable Populations, 2013, Administration, Adult, Awad Magdi H, Bronchodilator Agents/administration & dosage, Cholinergic Antagonists/administration & dosage, chronic obstructive pulmonary disease, Chronic Obstructive/*diagnosis/drug therapy/epidemiology/physiopathology, COPD, Dai Allen, Department of Pharmacy Practice, Female, Forced Expiratory Volume, Gemmel David J, Ghattas Christian, Humans, Inhalation, International journal of chronic obstructive pulmonary disease, Lung/drug effects/*physiopathology, Male, Medically Uninsured, Middle Aged, misdiagnosis, NEOMED College of Pharmacy, Ohio/epidemiology, over diagnosis, Predictive Value of Tests, Prevalence, Pulmonary Disease, Retrospective Studies, Risk Factors, Smoking/adverse effects/epidemiology, Spirometry, underserved, uninsured, Vital Capacity

Safety and efficacy of cangrelor, an intravenous, short-acting platelet inhibitor in patients requiring coronary artery bypass surgery.

OBJECTIVE: Oral P2Y(1)(2) platelet receptor inhibitors are a cornerstone of reducing complications in patients with acute coronary syndromes or coronary stents. Guidelines advocate discontinuing treatment with P2Y(1)(2) platelet receptor inhibitors…

Tags: 2013, 80 and over, Adenosine Monophosphate/administration & dosage/*analogs & derivatives, Administration, Adult, Aged, Angiolillo Dominick J, Blood Transfusion/*statistics & numerical data, Brtko Miroslav, Cannon Louis A, Chandna Harish, Chronos Nicholas, Combination/statistics & numerical data, Coronary Artery Bypass/*statistics & numerical data, Dietrich Markus, Drug Therapy, Drug-Related Side Effects and Adverse Reactions/epidemiology, Dyke Cornelius M, Female, Firstenberg Michael S, Holmes David R, Humans, Hutyra Martin, Injections, Intravenous, Liu Tiepu, Male, Manoukian Steven V, Middle Aged, Montalescot Gilles, Oral, Placebo Effect, Platelet Aggregation Inhibitors/administration & dosage, Postoperative Hemorrhage/*epidemiology/*prevention & control, Prats Jayne, Premedication/*statistics & numerical data, Prevalence, Price Matthew, Purinergic P2Y Receptor Antagonists/administration & dosage, Pyridines/*administration & dosage, Ramaiahm Chandrashekar, Risk Assessment, The heart surgery forum, Todd Meredith, Topo Eric J, Treatment Outcome, Tummala Pradyumna, United States/epidemiology, Voeltz Michele, Welsby Ian

Clinical implications of 750 mg, 5-day levofloxacin for the treatment of community-acquired pneumonia.

OBJECTIVE: To evaluate the time to symptom resolution and i.v.-to-p.o. transition in community-acquired pneumonia (CAP) patients treated with 750 mg or 500 mg levofloxacin. RESEARCH DESIGN: A retrospective, subset analysis of a multicenter,…

Topical brinzolamide (Azopt) versus placebo in the treatment of infantile nystagmus syndrome (INS).

PURPOSE: To test the hypothesis that the topical carbonic anhydrase inhibitor brinzolamide (Azopt) has beneficial effects versus placebo on measures of nystagmus and visual acuity in adult subjects with infantile nystagmus syndrome (INS). DESIGN:…

Catastrophic chest pain: blinded by cardiopulmonary disease.

A 53-year-old man with a history of diabetic foot ulcer, osteomyelitis, coronary artery disease, hypertension and hyperlipidaemia, presented with chest pain of 3 weeks duration. Eleven days earlier, the patient had had a drug-eluting stent (DES)…

Oxybutynin 3% gel for the treatment of primary focal hyperhidrosis in adolescents and young adults.

BACKGROUND/OBJECTIVES: There are no reliably effective, well-tolerated topical agents for the treatment of hyperhidrosis. We sought to evaluate the efficacy and tolerability of oxybutynin 3% gel in adolescents and young adults with primary focal…

Intranasal lidocaine for the treatment of migraine headache: a randomized, controlled trial.

OBJECTIVE: To evaluate the effect of intranasal lidocaine for immediate relief (5 minutes) of migraine headache pain. METHODS: A randomized, double-blind, placebo-controlled clinical trial at two university-affiliated community teaching hospitals…

Treatment of Fordyce spots with bichloracetic acid.

Tags: 2008, Administration, Adult, Brodell Robert T, Caustics/*administration & dosage, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], Dichloroacetic Acid/*administration & dosage, Humans, Lip, Male, Plotner Alisha N, Sebaceous Gland Diseases/*drug therapy, Topical

Skin sterility after application of a vapocoolant spray.

BACKGROUND: Refrigerant sprays have been widely used to reduce pain in the office setting. However, more recently, their use has been limited by both concern regarding flammability and questions of bacterial contamination. OBJECTIVE: We investigated…

Are nasal steroids safe?

Nasal steroids have emerged as an integral part of rhinitis management. Most studies have shown no evidence of significant hypothalamic-pituitary-adrenal axis suppression from nasal steroid use, at least based on dynamic testing. Bone mineral density…

Tags: 2003, Administration, Anti-Inflammatory Agents/*administration & dosage/*adverse effects/therapeutic use, Current opinion in otolaryngology & head and neck surgery, Humans, Inhalation, Intranasal, Mehle Mark E, Rhinitis/*drug therapy

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.

BACKGROUND: Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. METHODS: A total of 863 adults with…

Tags: *clinical trial, *Community-acquired, *Pneumonia, *solithromycin, *Streptococcus pneumoniae, 2016, 80 and over, Administration, Adult, Aged, Anti-Bacterial Agents/*administration & dosage/adverse effects, Bacterial, Bacterial/diagnosis/*drug therapy/*microbiology, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/diagnosis/*drug therapy/*microbiology, Comorbidity, Das Anita F, Department of Internal Medicine, Drug Resistance, Female, Fernandes Prabhavathi, File Thomas M Jr, Fluoroquinolones/*administration & dosage/adverse effects, Gonong Joven Roque V, Humans, Intravenous, Jamieson Brian D, Keedy Kara, Macrolides/*administration & dosage/adverse effects, Male, Microbial Sensitivity Tests, Middle Aged, Moxifloxacin, NEOMED College of Medicine, Oldach David, Oral, Pneumonia, Rewerska Barbara, Sheets Amanda, Taylor David, Treatment Outcome, Triazoles/*administration & dosage/adverse effects, Vucinic-Mihailovic Violeta

Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia.

BACKGROUND: Ceftaroline, the active form of ceftaroline fosamil, is a broad-spectrum cephalosporin with bactericidal activity against pathogens causing community-acquired pneumonia (CAP), including Streptococcus pneumoniae. Ceftaroline was evaluated…

Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model.

Impaired wound healing is characteristic of diabetic patients. Potential reasons include poor inflammatory response, granulation tissue formation, and abnormal patterns of cytokine release and response. Vascular endothelial growth factor, abnormally…

Inhaled corticosteroid use in asthmatic children receiving Ohio Medicaid: trend analysis, 1997-2001.

BACKGROUND: In 1997, national guidelines emphasized that inhaled corticosteroids (ICSs) are key therapy for individuals with all classes of persistent asthma, including children. OBJECTIVE: To examine the effect of these guidelines via time-trend…

Tags: 2008, Administration, Adolescent, Adrenal Cortex Hormones/administration & dosage/*therapeutic use, African Americans/statistics & numerical data, Ambulatory Care/statistics & numerical data, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Asthma/diagnosis/*drug therapy/ethnology, Bean Judy A, Child, Cross-Sectional Studies, Drug Utilization/statistics & numerical data/trends, Emergency Service, European Continental Ancestry Group/statistics & numerical data, Female, Heaton Pamela C, Hospital/statistics & numerical data, Hospitalization/statistics & numerical data, Humans, Infant, Inhalation, Male, Medicaid/*statistics & numerical data, Moomaw Charles J, Newborn, Ohio, Preschool, Regression Analysis, Retrospective Studies, Ruddy Richard M, Sex Factors, Stevenson Michelle D, United States

Oral contraceptive failure rates and oral antibiotics.

BACKGROUND: Despite anecdotal evidence of a possibility of decreased effectiveness of oral contraceptives (OCs) with some antibiotics, it is not known whether antibiotic use in dermatologic practices engenders any increased risk of accidental…

Reversible ectropion after long-term use of topical tretinoin on photodamaged skin.

Tags: 1992, Administration, Aged, Asselin D, Brodell L P, Brodell R T, Cutaneous, Ectropion/*chemically induced, Face, Female, Humans, Journal of the American Academy of Dermatology, Middle Aged, Skin Aging/*drug effects, Tretinoin/administration & dosage/*adverse effects

A subtherapeutic international normalized ratio despite increasing doses of warfarin: could this be malabsorption?

OBJECTIVE: To describe a case of warfarin resistance apparently caused by malabsorption and to review the literature regarding warfarin resistance. CASE SUMMARY: A 28-year-old renal transplant patient with systemic lupus erythematosus was admitted…

Awake aortic aneurysm repair in patients with severe pulmonary disease.

BACKGROUND: We report the use of retroperitoneal aortic aneurysm repair utilizing exclusive regional anesthesia (no intubation or inhalation anesthetic) in high pulmonary risk patients. METHODS: Six patients were retrospectively reviewed. Pulmonary…

Tags: *Consciousness, 1999, Abdominal/*surgery, Administration, Aged, Albuterol/administration & dosage/therapeutic use, American journal of surgery, Anesthesia, Aortic Aneurysm, Blood Loss, Bronchodilator Agents/administration & dosage/therapeutic use, Critical Care, Epidural, Forced Expiratory Volume/physiology, General, Hirko M K, Home Care Services, Hospitalization, Humans, Hypnotics and Sedatives/administration & dosage, Iliac Aneurysm/*surgery, Inhalation, Intravenous, Koler A J, Labat G C, Length of Stay, Lung Diseases/*complications/drug therapy/therapy, McGregor W E, Oxygen Inhalation Therapy, Perni V, Retroperitoneal Space, Retrospective Studies, Risk Factors, Rubin J R, Safety, Steroids/administration & dosage/therapeutic use, Surgical, Theophylline/administration & dosage/therapeutic use, Time Factors, Vital Capacity/physiology

Depression screening using health questionnaires in patients receiving oral isotretinoin for acne vulgaris.

Isotretinoin is used to treat severe and recalcitrant acne. Possible side effects include depression, suicide, and suicidal ideation; however, other studies suggest isotretinoin may improve mood and quality of life. Although iPLEDGE consenting warns…

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