Browse Items · NEOMED Bibliography Database

Changes in instrumentally and classically conditioned limb-flexion responses following inferior olivary lesions and olivocerebellar tractotomy in the cat.

Lesions were placed in various parts of the inferior olivary nucleus and olivocerebellar tract in an attempt to define further the role of the inferior olive in the performance of a conditioned limb-flexion response (LFR) in cats. Thirty-two cats…

A method for calculating current source density (CSD) analysis without resorting to recording sites outside the sampling volume.

This article is part of a study on cortical microcircuitry in which flash evoked potentials (FEPs) were recorded from the anesthetized rat visual cortex. The FEPs were subjected to current source density analysis (CSD). One of the limitations of the…

Tags: 1988, Action Potentials, Animals, DiScenna P G, Electric Stimulation, Journal of neuroscience methods, Models, Neurological, Neurophysiology/*methods, Photic Stimulation, Teyler T J, Vaknin G, Visual Cortex/*physiology

The development of long-term potentiation in hippocampus and neocortex.

The development of long-term potentiation (LTP), an enduring alteration in synaptic efficacy following afferent activation, was examined in CA1 hippocampus and primary visual cortex of rat. Both regions show little LTP prior to postnatal day 5,…

Comparative aspects of hippocampal and neocortical long-term potentiation.

Long-term potentiation (LTP) is a candidate for the synaptic alternations underlying memory storage in the mammalian CNS. In this chapter LTP in hippocampus and in visual neocortex are compared. Comparisons of the optimal tetanus parameters revealed…

Tags: 1989, Action Potentials, Animals, Electric Stimulation, Evoked Potentials, Hippocampus/*physiology, Journal of neuroscience methods, Memory/physiology, N-Methyl-D-Aspartate, Neurotransmitter/*physiology, Receptors, Teyler T J, Visual Cortex/*physiology

A critical period for long-term potentiation in the developing rat visual cortex.

The in vitro rodent visual cortical slice preparation demonstrates a critical period for long-term potentiation (LTP). Current source density (CSD) analysis reveals peak potentiation of both supra-(layers II-III) and infragranular (layers V) layers…

Tags: 1988, Aging, Animals, Brain research, Electric Stimulation, In Vitro Techniques, Neuronal Plasticity, Newborn, Perkins A T 4th, Rats, Teyler T J, Visual Cortex/*growth & development/physiology

Metabotropic glutamate receptor antagonist, (R,S)-alpha-methyl-4-carboxyphenyglycine, blocks two distinct forms of long-term potentiation in area CA1 of rat hippocampus.

The necessity of metabotropic glutamate receptors (mGluRs) in the induction of long-term potentiation (LTP) has recently been questioned. We examined the effect of (R,S)-alpha-methyl-4-caboxyphenylglycine (MCPG), a selective mGluR antagonist, on two…

Tags: 1995, Animals, Benzoates/*pharmacology, Calcium Channels/drug effects/metabolism/physiology, Electric Stimulation, Electrophysiology, Excitatory Amino Acid Antagonists/*pharmacology, Glycine/*analogs & derivatives/pharmacology, Grover L M, Hippocampus/drug effects/*physiology, In Vitro Techniques, Ion Channel Gating/drug effects, Little Z, Long-Term Potentiation/*drug effects, Metabotropic Glutamate/*antagonists & inhibitors, Neuroscience letters, Rats, Receptors, Teyler T J

Differential effects of NMDA receptor antagonist APV on tetanic stimulation induced and calcium induced potentiation.

Enduring synaptic potentiation can be induced in area CA1 of hippocampus by tetanic stimulation and by exposure to a medium containing high Ca2+ concentration. Both tetanic stimulation and high Ca2+ induce potentiation through voltage-dependent,…

Tags: 1990, 2-Amino-5-phosphonovalerate/*pharmacology, Action Potentials/drug effects, Animals, Calcium/*pharmacology, Electric Stimulation, Grover L M, Hippocampus/drug effects/*physiology, In Vitro Techniques, N-Methyl-D-Aspartate, Neuronal Plasticity/*drug effects, Neuroscience letters, Neurotransmitter/antagonists & inhibitors/*physiology, Receptors, Teyler T J

Aspartame exposure and in vitro hippocampal slice excitability and plasticity.

Aspartame (APM) is a low-calorie sweetener recently approved and released for widespread use in the United States. However, concerns still exist that APM consumption may be responsible for adverse neurological and psychological effects in some…

Tags: 1988, Animals, Aspartame/*toxicity, Dipeptides/*toxicity, Electric Stimulation, Electrophysiology, Female, Fountain S B, Fundamental and applied toxicology : official journal of the Society of Toxicology, Hennes S K, Hippocampus/*drug effects/physiopathology, Neuronal Plasticity/*drug effects, Neurons/drug effects, Rats, Teyler T J, Time Factors

The neural basis of the behaviorally relevant N1 component of the somatosensory-evoked potential in SI cortex of awake monkeys: evidence that backward cortical projections signal conscious touch sensation.

Studies of touch intensity discrimination in monkeys have identified a component of the somatosensory-evoked cortical potential, N1, generated within 50 ms of the stimulus, that predicts their behavioral performance. This study employed…

Induction of LTP in rat primary visual cortex: tetanus parameters.

Long-term potentiation (LTP), intensively studied in the hippocampus as a possible mnemonic device, has begun to be studied in the neocortex. In this study the effects of varying tetanic stimulus parameters on LTP of field potentials recorded from…

Tags: 1989, Animals, Berry R L, Brain research, Electric Stimulation, Female, Han T Z, In Vitro Techniques, Male, Rats, Reaction Time/physiology, Teyler T J, Visual Cortex/*physiology

Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanism.

Tonic inhibition mediated by extrasynaptic GABA(A) receptors (GABA(A)Rs) has emerged as a novel form of neural inhibition in the CNS. However, little is known about its presence and function in the auditory system. Using whole-cell recordings in…

Synaptic Inhibition in Avian Interaural Level Difference Sound Localizing Neurons.

Synaptic inhibition plays a fundamental role in the neural computation of the interaural level difference (ILD), an important cue for the localization of high-frequency sound. Here, we studied the inhibitory synaptic currents in the chicken posterior…

Tags: *dorsal nucleus of the lateral lemniscus, *GABAA receptor, *interaural level difference, *reversal potential, *synaptic inhibition, 2016, Acoustic Stimulation/methods, Animals, Anions/metabolism, Avian Proteins/metabolism, Brain Stem/cytology/drug effects/*physiology, Chick Embryo, Chlorides/metabolism, Curry Rebecca J, Department of Anatomy & Neurobiology, Electric Stimulation, eNeuro, Female, GABA-A/metabolism, gamma-Aminobutyric Acid/metabolism, Glycine/metabolism, Intracellular Space/drug effects/metabolism, Lu Yong, Male, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons/cytology/drug effects/*physiology, Patch-Clamp Techniques, Receptors, Sound Localization/drug effects/*physiology, Symporters/metabolism, Synaptic Transmission/drug effects/*physiology, Tissue Culture Techniques

Upper-Limb Recovery After Stroke: A Randomized Controlled Trial Comparing

BACKGROUND AND PURPOSE: This study compared the effect of cyclic neuromuscular electrical stimulation (NMES), electromyographically (EMG)-triggered NMES, and sensory stimulation on motor impairment and activity limitations in patients with upper-limb…

Role of HCO3- ions in depolarizing GABAA receptor-mediated responses in pyramidal cells of rat hippocampus.

1. Activation of GABAA receptors can produce both hyperpolarizing and depolarizing responses in CA1 pyramidal cells. The hyperpolarizing response is mediated by a Cl- conductance, but the ionic basis of the depolarizing response is not clear. We…

Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.

GABAergic transmission in the avian cochlear nucleus magnocellularis (NM) of the chick is subject to modulation by gamma-aminobutyric acid type B (GABA(B)) autoreceptors. Here, I investigated modulation of GABAergic transmission in NM by metabotropic…

Tags: 2-Amino-5-phosphonovalerate/pharmacology, 2007, Amino Acids/pharmacology, Animals, Chickens/*physiology, Cochlear Nucleus/*cytology/*physiology, Department of Anatomy & Neurobiology, Electric Stimulation, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/physiology, GABA-B Receptor Agonists, GABA-B Receptor Antagonists, GABA-B/physiology, gamma-Aminobutyric Acid/*physiology, Glycine/analogs & derivatives/pharmacology, In Vitro Techniques, Journal of neurophysiology, Kinetics, Lu Yong, Membrane Potentials/drug effects, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism/physiology, Models, NEOMED College of Medicine, Neurological, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Resorcinols/pharmacology, Synapses/physiology, Synaptic Transmission/*physiology, Xanthenes/pharmacology

Role of adenosine in heterosynaptic, posttetanic depression in area CA1 of hippocampus.

Conditioning stimulation of afferent fibers in hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of responses evoked by stimulation of an independent set of afferent fibers. PTD was present within 5 s of conditioning…

The development of GABAB-mediated activity in the rat dentate gyrus.

We examined the effects of GABAB receptor activation in the dentate gyrus of hippocampal slices prepared from 6-8-day-old rat pup. Baclofen (0.25-1.0 microM), a GABAB agonist, rapidly and potently disinhibited the developing dentate, similar to its…

Tags: 1994, Animals, Baclofen/analogs & derivatives/pharmacology, Brain research. Developmental brain research, DiScenna P G, Electric Stimulation, Evoked Potentials/drug effects, GABA-A Receptor Antagonists, GABA-A/drug effects/physiology, GABA-B Receptor Antagonists, GABA-B/*metabolism, Hippocampus/*growth & development/*metabolism, In Vitro Techniques, Nowicky A V, Organophosphorus Compounds/pharmacology, Rats, Receptors, Teyler T J

Induction of NMDA receptor-independent long-term potentiation (LTP) in visual cortex of adult rats.

The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in…

Tags: 1992, Animals, Aroniadou V A, Brain research, Electric Stimulation, Evoked Potentials/physiology, In Vitro Techniques, N-Methyl-D-Aspartate/antagonists & inhibitors/drug effects/*physiology, Neuronal Plasticity/drug effects/*physiology, Rats, Receptors, Synapses/physiology, Teyler T J, Visual Cortex/*physiology

The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex.

The purpose of the present study was to improve our understanding of the role of NMDA receptors in neocortical synaptic plasticity. In slices of rat visual cortex the field potential elicited in layer III in response to white matter stimulation…

Depotentiation of vdccLTP requires NMDAR activation.

Long-term potentiation is an enduring increase in synaptic efficacy following repeated stimulation of afferent fibers that is thought to underlie memory. In area CA1 of the hippocampus at least two forms of synaptic potentiation coexist at the same…

Presynaptic mechanism for heterosynaptic, posttetanic depression in area CA1 of rat hippocampus.

Conditioning stimulation applied to afferent fibers in stratum radiatum or stratum oriens of hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of excitatory postsynaptic potentials (EPSPs). PTD amounted to a

NMDA receptor-independent LTP in basal versus apical dendrites of CA1 pyramidal cells in rat hippocampal slice.

The ability of hippocampal CA1 basal synapses to express N-methyl-D-aspartate (NMDA) receptor-independent long-term potentiation (non-NMDA LTP) was studied and compared to the simultaneously induced apical dendritic non-NMDA LTP. Non-NMDA LTP in…

Inhibition of long-term potentiation development in rat hippocampal slice by alpha 2-macroglobulin, an acute-phase protein in the brain.

Alpha-2-macroglobulin (alpha 2M) in the rat and human brain is an acute-phase protein synthesized primarily by astrocytes, and it has been implicated in Alzheimer's disease and other neuropathological processes. The activated forms of alpha 2M, but…

Tags: 1996, alpha-Macroglobulins/*pharmacology, Animals, Cavus I, Electric Stimulation, Hippocampus/drug effects/*physiology, Humans, In Vitro Techniques, Journal of neuroscience research, Koo P H, Long-Term Potentiation/*drug effects, Methylamines/pharmacology, Neurites/drug effects/*physiology, Pyramidal Cells/drug effects/physiology, Rats, Synapses/drug effects/physiology, Synaptic Transmission/drug effects, Teyler T J, Time Factors

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