Browse Items (14 total)
- Tags: Patch-Clamp Techniques
Interplay between low threshold voltage-gated K(+) channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis.
Tags: 2014, Animals, Auditory Pathways/*physiology, Chick Embryo, Department of Anatomy & Neurobiology, Frontiers in neural circuits, GABAergic inhibition, Hamlet William R, Inhibitory Postsynaptic Potentials/*physiology, interaural time difference, IPSC, IPSP, Liu Yu-Wei, Lu Yong, NEOMED College of Medicine, Neurons/*physiology, Patch-Clamp Techniques, Potassium Channels, Sound Localization/physiology, Synaptic Transmission/*physiology, Tang Zheng-Quan, tonotopy, voltage-gated low-threshold potassium current, Voltage-Gated/*physiology, whole-cell patch
Ambient GABA-activated tonic inhibition sharpens auditory coincidence detection via a depolarizing shunting mechanism.
Tags: 2011, Animals, Auditory Pathways/*physiology, Blotting, Chick Embryo, Department of Anatomy & Neurobiology, Dinh Emilie Hoang, Electric Stimulation, GABA-A/*physiology, gamma-Aminobutyric Acid/*physiology, Inhibitory Postsynaptic Potentials, Lu Yong, Membrane Potentials/physiology, NEOMED College of Medicine, Neural Inhibition/*physiology, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Shi Wei, Tang Zheng-Quan, The Journal of neuroscience : the official journal of the Society for Neuroscience, Western
Synaptic Inhibition in Avian Interaural Level Difference Sound Localizing Neurons.
Tags: *dorsal nucleus of the lateral lemniscus, *GABAA receptor, *interaural level difference, *reversal potential, *synaptic inhibition, 2016, Acoustic Stimulation/methods, Animals, Anions/metabolism, Avian Proteins/metabolism, Brain Stem/cytology/drug effects/*physiology, Chick Embryo, Chlorides/metabolism, Curry Rebecca J, Department of Anatomy & Neurobiology, Electric Stimulation, eNeuro, Female, GABA-A/metabolism, gamma-Aminobutyric Acid/metabolism, Glycine/metabolism, Intracellular Space/drug effects/metabolism, Lu Yong, Male, NEOMED College of Medicine, Neural Inhibition/drug effects/*physiology, Neurons/cytology/drug effects/*physiology, Patch-Clamp Techniques, Receptors, Sound Localization/drug effects/*physiology, Symporters/metabolism, Synaptic Transmission/drug effects/*physiology, Tissue Culture Techniques
Development of GPCR modulation of GABAergic transmission in chicken nucleus laminaris neurons.
Tags: *Synaptic Transmission, 2012, Animals, Brain/*cytology, Chickens/*metabolism, Department of Anatomy & Neurobiology, G-Protein-Coupled/*metabolism, GABA-A/metabolism, GABA-B/metabolism, gamma-Aminobutyric Acid/*metabolism, Lu Yong, Metabotropic Glutamate/metabolism, NEOMED College of Medicine, Neurons/*metabolism, Patch-Clamp Techniques, PloS one, Receptors, Synapses/metabolism, Tang Zheng-Quan
Endogenous mGluR activity suppresses GABAergic transmission in avian cochlear nucleus magnocellularis neurons.
Tags: 2-Amino-5-phosphonovalerate/pharmacology, 2007, Amino Acids/pharmacology, Animals, Chickens/*physiology, Cochlear Nucleus/*cytology/*physiology, Department of Anatomy & Neurobiology, Electric Stimulation, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/physiology, GABA-B Receptor Agonists, GABA-B Receptor Antagonists, GABA-B/physiology, gamma-Aminobutyric Acid/*physiology, Glycine/analogs & derivatives/pharmacology, In Vitro Techniques, Journal of neurophysiology, Kinetics, Lu Yong, Membrane Potentials/drug effects, Metabotropic Glutamate/agonists/antagonists & inhibitors/*metabolism/physiology, Models, NEOMED College of Medicine, Neurological, Neurons/*physiology, Patch-Clamp Techniques, Receptors, Resorcinols/pharmacology, Synapses/physiology, Synaptic Transmission/*physiology, Xanthenes/pharmacology
Postinhibitory rebound neurons and networks are disrupted in retrovirus-induced spongiform neurodegeneration.
Tags: 2014, Action Potentials/physiology, Animals, Antigens/metabolism, auditory midbrain, Calcium/metabolism, Davey Robert A, Department of Integrative Medical Sciences, env/metabolism, Experimental/physiopathology, Gene Products, Hearing Loss/physiopathology, Inferior Colliculi/physiopathology/virology, inferior colliculus, Journal of neurophysiology, Leukemia, Leukemia Virus, Li Ying, Lynch William P, Membrane Potentials/physiology, Mice, Microglia/physiology/virology, Murine/*physiology, NEOMED College of Medicine, Neural Pathways/physiopathology, Neurodegenerative Diseases/*physiopathology, Neuroglia/physiology/virology, Neurons/*physiology/virology, Patch-Clamp Techniques, postinhibitory rebound neurons, Proteoglycans/metabolism, Retroviridae Infections/*physiopathology/virology, retrovirus, Sivaramakrishnan Shobhana, Tissue Culture Techniques, Tumor Virus Infections/*physiopathology/virology, Voltage-Sensitive Dye Imaging, voltage-sensitive dyes
Activation of metabotropic glutamate receptor 1 dimers requires glutamate binding in both subunits.
Tags: 2005, Blotting, Calcium Channels/drug effects/metabolism, Department of Integrative Medical Sciences, DNA/biosynthesis/genetics, Dose-Response Relationship, Drug, Fluorescent Antibody Technique, Genes, Glutamic Acid/*metabolism, Humans, Kammermeier Paul J, Membrane Potentials/drug effects, Metabotropic Glutamate/genetics/*metabolism, myc/genetics, NEOMED College of Medicine, Patch-Clamp Techniques, Plasmids/genetics, Receptors, Signal Transduction/drug effects, Superior Cervical Ganglion/cytology/drug effects/metabolism, Sympathetic Nervous System/cytology/drug effects/metabolism, The Journal of pharmacology and experimental therapeutics, Western, Yun June
Intrinsic plasticity induced by group II metabotropic glutamate receptors via enhancement of high-threshold KV currents in sound localizing neurons.
Tags: 2016, Acoustic Stimulation/methods, Action Potentials/drug effects/physiology, Animals, Auditory Pathways/drug effects/*physiology, Brain/drug effects/physiology, Chick Embryo, Department of Anatomy & Neurobiology, Glutamic Acid/metabolism, Hamlet W R, Lu Y, metabotropic glutamate receptor, Metabotropic Glutamate/agonists/*metabolism, NEOMED College of Medicine, neuromodulation, Neuronal Plasticity/drug effects/*physiology, Neurons/drug effects/*physiology, Neuroscience, nucleus laminaris, Patch-Clamp Techniques, Potassium Channels, Potassium/metabolism, Protein Kinase C/metabolism, Receptors, Sound Localization/drug effects/*physiology, Tissue Culture Techniques, Type C Phospholipases/metabolism, voltage-gated potassium channel, Voltage-Gated/*metabolism
Regulation of glutamatergic and GABAergic neurotransmission in the chick nucleus laminaris: role of N-type calcium channels.
Tags: 2009, Animals, Auditory Pathways/cytology/drug effects/metabolism, Calcium Channel Blockers/pharmacology, Calcium Channels, Chick Embryo, Chickens, Cochlear Nucleus/cytology/drug effects/*metabolism, Department of Anatomy & Neurobiology, Excitatory Postsynaptic Potentials/drug effects/physiology, Functional Laterality/drug effects/physiology, gamma-Aminobutyric Acid/*metabolism, Glutamic Acid/*metabolism, Lu Y, N-Type/*metabolism, NEOMED College of Medicine, Neural Inhibition/physiology, Neurons/drug effects/metabolism, Neuroscience, omega-Conotoxin GVIA/pharmacology, Organ Culture Techniques, Patch-Clamp Techniques, Rhombencephalon/cytology/*metabolism, Synaptic Transmission/drug effects/*physiology
Localization and function of NK(3) subtype tachykinin receptors of layer V pyramidal neurons of the guinea-pig medial prefrontal cortex.
Tags: 2008, Animals, Autoradiography/methods, Dose-Response Relationship, Drug, Drug Interactions, Excitatory Amino Acid Antagonists/pharmacology, Excitatory Postsynaptic Potentials/drug effects/radiation effects, Guinea Pigs, In Vitro Techniques, Iodine Isotopes/pharmacokinetics, Male, Medd A M, Membrane Potentials/drug effects/physiology/radiation effects, Neurokinin B/analogs & derivatives/pharmacokinetics, Neurokinin-3/agonists/antagonists & inhibitors/*metabolism, Neuroscience, Patch-Clamp Techniques, Peptide Fragments/pharmacology, Prefrontal Cortex/*cytology, Protein Binding/drug effects, Pyramidal Cells/drug effects/*metabolism, Quinolines/pharmacology, Quinoxalines/pharmacology, Receptors, Simmons M A, Sobotka-Briner C D, Substance P/analogs & derivatives/pharmacology, Valine/analogs & derivatives/pharmacology
Early development of intrinsic and synaptic properties of chicken nucleus laminaris neurons.
Tags: 2008, Action Potentials/physiology, Aging/physiology, Animals, Auditory Pathways/cytology/*embryology/physiology, Auditory Perception/physiology, Body Patterning/physiology, Brain Stem/cytology/*embryology/physiology, Cell Differentiation/*physiology, Chick Embryo, Chickens, Cochlear Nucleus/cytology/*embryology/physiology, Department of Anatomy & Neurobiology, Excitatory Postsynaptic Potentials/physiology, Gao H, Lu Y, NEOMED College of Medicine, Neurons/cytology/*physiology, Neuroscience, Patch-Clamp Techniques, Potassium Channels, Sound Localization/physiology, Synapses/*physiology/ultrastructure, Time Factors, Voltage-Gated/physiology
Synaptic activity-induced Ca(2+) signaling in avian cochlear nucleus magnocellularis neurons.
Tags: 2012, Animals, Calcium Signaling/*physiology, Chick Embryo, Chickens, Cochlear Nucleus/*metabolism, Department of Anatomy & Neurobiology, GABA-A/metabolism, Inhibitory Postsynaptic Potentials/physiology, Lu Yong, NEOMED College of Medicine, Neurons/*metabolism, Neuroscience research, Organ Culture Techniques, Patch-Clamp Techniques, Receptors, Synapses/*metabolism, Synaptic Transmission/*physiology, Tang Zheng-Quan, Wang Lie-Cheng
Metabotropic glutamate and GABA receptors modulate cellular excitability and glutamatergic transmission in chicken cochlear nucleus angularis neurons.
Tags: *Cellular excitability, *GABA(B)R, *mGluR, *Neuromodulation, *Nucleus angularis, *Synaptic Transmission, 2017, Action Potentials/drug effects, Animals, Chick Embryo, Cochlear Nucleus/cytology/*physiology, Department of Anatomy & Neurobiology, Excitatory Postsynaptic Potentials/drug effects, GABA-B Receptor Agonists/pharmacology, GABA-B/*physiology, Glutamic Acid/*physiology, Hearing research, Lu Yong, Metabotropic Glutamate/agonists/classification/*physiology, NEOMED College of Medicine, Neurons/drug effects/physiology, Patch-Clamp Techniques, Receptors, Shi Wei, Synaptic Transmission/drug effects
4-Hydroxynonenal dependent alteration of TRPV1-mediated coronary microvascular signaling.
Tags: *4-Hydroxynonenal, *Coronary regulation, *Lipid peroxidation, *Post-translational modification, *Protein Processing, *Reactive oxygen species, *Signal Transduction, *TRPV1, 2016, Action Potentials/drug effects, Aldehydes/antagonists & inhibitors/metabolism/*pharmacology, Animal, Animals, Blood Flow Velocity, Bratz Ian N, Calcium Signaling/drug effects, Cappelli Holly C, Capsaicin/*pharmacology, Cardiovascular Agents/*pharmacology, Connell Patrick J, Coronary Circulation/drug effects, Coronary Vessels/metabolism/physiopathology, Cysteine/genetics/metabolism, Damron Derek S, DelloStritto Daniel J, Department of Integrative Medical Sciences, Diabetes Mellitus/drug therapy/*metabolism/physiopathology, Disease Models, Fahmy Joseph N, Femoral Artery/metabolism/physiopathology, Free radical biology & medicine, Geldenhuys Werner J, HEK293 Cells, Humans, Inbred C57BL, Lipid Peroxidation, Male, Mice, NEOMED College of Medicine, Patch-Clamp Techniques, Post-Translational, Sinharoy Pritam, Thodeti Charles K, TRPV Cation Channels/genetics/*metabolism, Vasodilation/drug effects