Presynaptic mechanism for heterosynaptic, posttetanic depression in area CA1 of rat hippocampus.

Presynaptic mechanism for heterosynaptic, posttetanic depression in area CA1 of rat hippocampus.

Grover L M; Teyler T J

Synapse (New York, N.Y.)

1993

1993-10

Conditioning stimulation applied to afferent fibers in stratum radiatum or stratum oriens of hippocampal area CA1 produced heterosynaptic, posttetanic depression (PTD) of excitatory postsynaptic potentials (EPSPs). PTD amounted to a

Afferent/drug effects; Animals; Electric Stimulation; Electrophysiology; Evoked Potentials/physiology; Glutamate/drug effects; Glutamates/pharmacology; Glutamic Acid; Hippocampus/drug effects/*physiology; In Vitro Techniques; Membrane Potentials/physiology; N-Methyl-D-Aspartate/antagonists & inhibitors; Neuronal Plasticity/drug effects/physiology; Neurons; Presynaptic/drug effects/*physiology; Pyramidal Cells/drug effects; Rats; Receptors; Synapses/drug effects/*physiology

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

149–157

2

15