Induction of NMDA receptor-independent long-term potentiation (LTP) in visual cortex of adult rats.

Induction of NMDA receptor-independent long-term potentiation (LTP) in visual cortex of adult rats.

Aroniadou V A; Teyler T J

Brain research

1992

1992-07

The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in its induction. The field potential elicited in layer III in response to stimulation of the subcortical white matter consisted of a component with peak latency 5-8 ms (N1) and, in most slices, a second component with peak latency

Animals; Electric Stimulation; Evoked Potentials/physiology; In Vitro Techniques; N-Methyl-D-Aspartate/antagonists & inhibitors/drug effects/*physiology; Neuronal Plasticity/drug effects/*physiology; Rats; Receptors; Synapses/physiology; Visual Cortex/*physiology

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