Barrett's esophagus: an acquired condition with genetic predisposition.

Barrett's esophagus: an acquired condition with genetic predisposition.

Fahmy N; King J F

The American journal of gastroenterology

1993

1993-08

We describe four families with a strong familial expression of Barrett's/gastroesophageal reflux disease (GERD) complex spanning one to four generations with two to seven affected members per family. The purpose of this report is to highlight genetic trends in Barrett's esophagus, stress the importance of a family history in gastroesophageal reflux disease, and to call attention to unique features of familial Barrett's esophagus.

Female; Humans; Male; Middle Aged; Aged; Biopsy; Pedigree; Adenocarcinoma/genetics; Barrett Esophagus/*genetics/pathology; Esophageal Neoplasms/genetics; Esophagus/pathology; Gastroesophageal Reflux/*genetics; Genes; Dominant

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

1262–1265

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