Legionnaires disease with bacteremic coinfection

Title

Legionnaires disease with bacteremic coinfection

Creator

Tan M J; Tan J S; File T M

Publisher

Clinical Infectious Diseases

Date

2002
2002-09

Description

We describe 6 patients who had bacteremic community-acquired pneumonia and unsuspected Legionella pneumophila coinfection. We reviewed case records of patients who were diagnosed as having a recent Legionella infection on the basis of either the presence of L. pneumophila serogroup 1 antigen in urine or a 4-fold increase in L. pneumophila antibody level and with a blood culture that yielded a bacterium other than L. pneumophila. Three patients were diagnosed with legionellosis on the basis of the presence of antigen in urine, and 3 were diagnosed on the basis of a 4-fold increase in antibody titer. Of these 6 patients, 4 were infected with Streptococcus pneumoniae, 1 with Streptococcus pyogenes, and 1 with Enterobacter cloacae. L. pneumophila infection in these patients may have predisposed them to concomitant bacteremia. Initial empiric antimicrobial therapy for patients who live in areas of endemicity and who are smokers should be treated with antimicrobial agents that have activity against pneumococcus and Legionella species.

Subject

adults; community-acquired pneumonia; criteria; Immunology; infection; Infectious Diseases; influenza; legionella-pneumophila; measles; Microbiology; risk-factors; surveillance

Identifier

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

533-539

Issue

5

Volume

35

Citation

Tan M J; Tan J S; File T M, “Legionnaires disease with bacteremic coinfection,” NEOMED Bibliography Database, accessed September 21, 2021, https://neomed.omeka.net/items/show/7276.

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