A case of chronic paclitaxel administration in ovarian cancer

Title

A case of chronic paclitaxel administration in ovarian cancer

Creator

Von Gruenigen V E; Karlen J R; Waggoner S E

Publisher

Gynecologic Oncology

Date

2003
2003-06

Description

Background. Treatment with chemotherapeutic agents, after initial ovarian tumor debulking, and during recurrence, results in extended chemotherapy. When ovarian cancer recurs, chemotherapy is continued when patients respond to therapy. However, the disease may become stable. Stable disease is clinically relevant and no longer an indication of treatment failure. Case. A woman with advanced ovarian cancer was treated with cytoxan and cisplatin chemotherapy after having surgical cytoreduction. She progressed and was placed on monthly intravenous paclitaxel. After an initial partial response to therapy, she then went into a prolonged stable course of her disease. She subsequently received 67 cycles of monthly paclitaxel therapy. Conclusion. Chronic administration of paclitaxel resulted in prolonged stabilization of disease and was well tolerated. (C) 2003 Elsevier Science (USA). All rights reserved.

Subject

carcinoma; chronic therapy; cisplatin; cycles; cyclophosphamide; follow-up; free survival; gynecologic malignancies; Obstetrics & Gynecology; Oncology; ovarian-cancer; paclitaxel; phase-ii trial; platinum-based chemotherapy; single-agent paclitaxel

Format

Journal Article

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Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

532-535

Issue

3

Volume

89

Citation

Von Gruenigen V E; Karlen J R; Waggoner S E, “A case of chronic paclitaxel administration in ovarian cancer,” NEOMED Bibliography Database, accessed June 15, 2021, https://neomed.omeka.net/items/show/7417.

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