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Tags: VE-cadherin

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Mechanosensitive TRPV4 channels stabilize VE-cadherin junctions to regulate tumor vascular integrity and metastasis.

The transient receptor potential vanilloid 4 (TRPV4) channel is a mechanosensor in endothelial cells (EC) that regulates cyclic strain-induced reorientation and flow-mediated nitric oxide production. We have recently demonstrated that TRPV4…

Tags: 2019, Adapala Ravi K, Amin Vibhatsu, angiogenesis, Cancer letters, Cappelli Holly C, Department of Integrative Medical Sciences, Kanugula Anantha K, Mechanotransduction, Midha Priya, NEOMED College of Medicine, Paruchuri Sailaja, Sharma Priya, Stiffness, Thodeti Charles K, TRPV4, Vascular integrity, VE-cadherin

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