Prolactin Stimulates Dopamine Release From The Rat Corpus Striatum In The Absence Of Extracellular Calcium
Title
Prolactin Stimulates Dopamine Release From The Rat Corpus Striatum In The Absence Of Extracellular Calcium
Creator
Laping N J; Dluzen D E; Ramirez V D
Publisher
Neuroscience Letters
Date
1991
1991-12
Description
Prolactin (PRL) increased basal dopamine (DA) release and attenuated amphetamine (AMPH)-stimulated DA release in vitro from rat corpus striatum in a concentration-dependent manner with 10(-5) M PRL being the most effective. The effects of PRL on DA release were enhanced in the absence of extracellular calcium. PRL at 10(-5) M did not alter the DA post-superfusion content of the striatal tissue. These results indicate that the stimulatory effect of PRL on basal DA release does not require extra-cellular calcium and the inhibitory effect on AMPH-stimulated DA release is not due to depletion of DA stores.
Subject
amphetamine; behavior; binding-sites; brain; calcium; cerebrospinal-fluid; corpus striatum; dopamine; hypothalamus; in-vitro; Neurosciences & Neurology; prolactin; rat
Identifier
Format
Journal Article or Conference Abstract Publication
URL Address
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Rights
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Pages
1-4
Issue
1
Volume
134
Citation
Laping N J; Dluzen D E; Ramirez V D, “Prolactin Stimulates Dopamine Release From The Rat Corpus Striatum In The Absence Of Extracellular Calcium,” NEOMED Bibliography Database, accessed December 2, 2023, https://neomed.omeka.net/items/show/10648.