tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via

Title

tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via

Creator

Green J A; Ansari M Y; Ball H C; Haqqi Tariq M

Publisher

Osteoarthritis and Cartilage

Date

2020
2020-05-12

Description

OBJECTIVES: Recent studies have shown that tRNA-derived RNA fragments (tRFs) are novel regulators of post-transcriptional gene expression. However, the expression profiles and their role in post-transcriptional gene regulation in chondrocytes is unknown. Here, we determined tRFs expression profile and explored tRF-3003a role in post-transcriptional gene regulation in IL-1beta stimulated chondrocytes. METHODS: We used qPCR arrays to determine tRNAs and tRFs expression in age- and sex-matched primary human OA chondrocytes and TC28/I2 cells stimulated with

Subject

Chondrocyte; JAK3; Noncoding RNA; Osteoarthritis; Transfer RNA; tRNA-derived fragments

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

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ISSN

1522-9653 1063-4584

NEOMED College

NEOMED College of Medicine

NEOMED Department

Department of Anatomy & Neurobiology

Update Year & Number

June 2020 Update II

Citation

Green J A; Ansari M Y; Ball H C; Haqqi Tariq M, “tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via,” NEOMED Bibliography Database, accessed October 18, 2021, https://neomed.omeka.net/items/show/11092.

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