tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via
Title
tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via
Creator
Green J A; Ansari M Y; Ball H C; Haqqi Tariq M
Publisher
Osteoarthritis and Cartilage
Date
2020
2020-05-12
Description
OBJECTIVES: Recent studies have shown that tRNA-derived RNA fragments (tRFs) are novel regulators of post-transcriptional gene expression. However, the expression profiles and their role in post-transcriptional gene regulation in chondrocytes is unknown. Here, we determined tRFs expression profile and explored tRF-3003a role in post-transcriptional gene regulation in IL-1beta stimulated chondrocytes. METHODS: We used qPCR arrays to determine tRNAs and tRFs expression in age- and sex-matched primary human OA chondrocytes and TC28/I2 cells stimulated with
Subject
Chondrocyte; JAK3; Noncoding RNA; Osteoarthritis; Transfer RNA; tRNA-derived fragments
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Format
journalArticle
URL Address
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ISSN
1522-9653 1063-4584
NEOMED College
NEOMED College of Medicine
NEOMED Department
Department of Anatomy & Neurobiology
Update Year & Number
June 2020 Update II
Citation
Green J A; Ansari M Y; Ball H C; Haqqi Tariq M, “tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via,” NEOMED Bibliography Database, accessed May 10, 2024, https://neomed.omeka.net/items/show/11092.