Racial differences in performance-based function and potential explanatory factors among individuals with knee osteoarthritis.

Racial differences in performance-based function and potential explanatory factors among individuals with knee osteoarthritis.

Flowers PPE;Schwartz TA;Arbeeva L;Golightly YM;Pathak A;Cooke J;Gupta JJ;Callahan LF;Goode AP;Corsi M;Huffman KM;Allen KD

Arthritis Care & Research

2020

2020-09

Objective: In individuals with knee osteoarthritis (OA), self-reported physical function is poorer in African Americans than in whites, but whether this difference holds true for objective assessments is unclear. The purpose of this study was to examine racial differences in performance-based physical function as well as potential underlying factors contributing to these racial differences.; Methods: Participants with knee OA from a randomized controlled trial completed the 2-minute step test (2MST), timed-up-and-go (TUG), and 30-second chair stand (30s-CST) at baseline. Race differences in performance-based function were assessed by logistic regression. Separate models were adjusted for sets of demographic, socioeconomic, psychological health, and physical health variables.; Results: In individuals with knee OA (n = 322; 72% women, 22% African American, mean ± SD age 66 ± 11 years, mean ± SD body mass index 31 ± 8 kg/m 2 ), African Americans (versus whites) had greater unadjusted odds of poorer function (30s-CST odds ratio [OR] 2.79 [95% confidence interval (95% CI) 1.65-4.72], 2MST OR 2.37 [95% CI 1.40-4.03], and TUG OR 3.71 [95% CI 2.16-6.36]). Relationships were maintained when adjusted for demographic and psychological health covariates, but they were either partially attenuated or nonsignificant when adjusted for physical health and socioeconomic covariates.; Conclusion: African American adults with knee OA had poorer unadjusted performance-based function than whites. Physical health and socioeconomic characteristics diminished these differences, emphasizing the fact that these factors may be important to consider in mitigating racial disparities in function. (© 2019, American College of Rheumatology.)

Female; Humans; Male; Aged; Middle Aged; Socioeconomic Factors; Pain Measurement; African Americans; Body Mass Index; European Continental Ancestry Group; Exercise Test; Knee Joint/physiopathology; Osteoarthritis Knee/physiopathology; Physical Functional Performance

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

journalArticle

1196-1204

9

72

2151-4658

NEOMED College of Medicine Student

NEOMED Student Publications

September 2020 List