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Tags: Zhang Y C

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Nutrient Regulation Of Cyp7a1 Expression Links Bile Acid Synthesis To Maintain Metabolic Homeostasis And Prevent Diabetes And Obesity

Tags: 2011, Boehme S M, Chiang J, Gastroenterology & Hepatology, Hepatology, Journal Article or Conference Abstract Publication, Klaassen C D, Li T G, Ochoa A, Zhang Y C

Mechanism Of Tissue-specific Farnesoid X Receptor In Suppressing The Expression Of Genes In Bile-acid Synthesis In Mice

Activation of farnesoid X receptor (Fxr, Nr1h4) is a major mechanism in suppressing bile-acid synthesis by reducing the expression levels of genes encoding key bile-acid synthetic enzymes (e.g., cytochrome P450 [CYP]7A1/Cyp7a1 and CYP8B1/Cyp8b1).…

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