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Tags: spongiform neurodegeneration

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Astrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression

The ability of retroviruses (RVs) to cause neurodegeneration is critically dependent upon two activities of the envelope protein (Env). First, Env facilitates viral genome delivery to CNS target cells through receptor binding and membrane fusion.…

Tags: 2019, Astrocytes, Cardona Sandra M, Das Alvin S, Department of Integrative Medical Sciences, Dunphy Jaclyn M, Frontiers in neuroscience, glia, Journal Article, Lynch Connor R, Lynch William P, NEOMED College of Medicine, neural progenitor cells, Neural stem cells, neurotropism, November 2019 Update, retrovirus, spongiform neurodegeneration, virus suppression

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