The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease.

Title

The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease.

Creator

Obrenovich Mark; Tabrez Shams; Siddiqui Bushra; McCloskey Benjamin; Perry George

Publisher

Microorganisms

Date

2020
2020-03-31

Description

There is a strong cerebrovascular component to brain aging, Alzheimer disease, and vascular dementia. Foods, common drugs, and the polyphenolic compounds contained in wine modulate health both directly and through the gut microbiota. This observation and novel findings centered on nutrition, biochemistry, and metabolism, as well as the newer insights we gain into the microbiota-gut-brain axis, now lead us to propose a shunt to this classic triad, which involves the heart and cerebrovascular systems. The French paradox and prosaic foods, as they relate to the microbiota-gut-brain axis and neurodegenerative diseases, are discussed in this manuscript, which is the second part of a two-part series of concept papers addressing the notion that the microbiota and host liver metabolism all play roles in brain and heart health.

Subject

Alzheimer disease; brain; cerebrovascular; co-metabolism; French paradox; heart; microbiota-gut-brain axis; Parkinson's disease; polyphenol; prosaic foods; red wine; trimethylamine-N-oxide (TMANO/TMAO)

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Format

journalArticle

Search for Full-text

Users with a NEOMED Library login can search for full-text journal articles at the following url: https://libraryguides.neomed.edu/home

Issue

4

Volume

8

ISSN

2076-2607 2076-2607

NEOMED College

NEOMED College of Medicine

NEOMED Department

NEOMED Student Publications

Update Year & Number

June 2020 Update I

Citation

Obrenovich Mark; Tabrez Shams; Siddiqui Bushra; McCloskey Benjamin; Perry George, “The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease.,” NEOMED Bibliography Database, accessed November 28, 2021, https://neomed.omeka.net/items/show/11041.

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