Circadian rhythms in liver metabolism and disease.

Title

Circadian rhythms in liver metabolism and disease.

Creator

Ferrell Jessica M; Chiang John Y L

Publisher

Acta pharmaceutica Sinica. B

Date

2015
2015-03

Description

Mounting research evidence demonstrates a significant negative impact of circadian disruption on human health. Shift work, chronic jet lag and sleep disturbances are associated with increased incidence of metabolic syndrome, and consequently result in obesity, type 2 diabetes and dyslipidemia. Here, these associations are reviewed with respect to liver metabolism and disease.

Subject

ARC; arcuate nucleus; BMAL1; brain and muscle ARNT-like 1; CAR; cholesterol 7alpha-hydroxylase; circadian locomotor output cycles kaput; Circadian rhythm; CLOCK; constitutive androstane receptor; CRY; cryptochrome; CYP7A1; CYPs; cytochrome P450 enzymes; D-site binding protein; DBP; E-box; emergency medical technician; EMT; enhance box; FAA; familial advanced sleep-phase syndrome; farnesoid-X receptor; FASPS; FEO; food anticipatory activity; food entrainable oscillator; forkhead box O3; FOXO3; FXR; G protein-coupled bile acid receptor; glucose transporter 2; GLUT2; HDAC3; hepatic leukemia factor; HIP; histone deacetylase 3; HLF; hypoxia inducing protein; LDL; Liver; liver receptor homolog 1; low-density lipoprotein; LRH1; Metabolic syndrome; NAD+; nicotinamide adenine dinucleotide; PER; period; retinohypothalamic tract; retinoid-related orphan receptor alpha; RHT; ROR-response element; RORalpha; RORE; SCN; SHP; SIRT1; sirtuin 1; small heterodimer partner; suprachiasmatic nucleus; TEF; TGR5; thyrotroph embryonic factor; transcriptional translational feedback loop; TTFL; Type 2 diabetes

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

113–122

Issue

2

Volume

5

Citation

Ferrell Jessica M; Chiang John Y L, “Circadian rhythms in liver metabolism and disease.,” NEOMED Bibliography Database, accessed October 20, 2021, https://neomed.omeka.net/items/show/3469.

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