A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.

Title

A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.

Creator

Han Shuxin; Li Tiangang; Ellis Ewa; Strom Stephen; Chiang John Y L

Publisher

Molecular endocrinology (Baltimore, Md.)

Date

2010
2010-06

Description

Vitamin D receptor (VDR) is activated by natural ligands, 1alpha,

Subject

Calcitriol/*metabolism; Calcitriol/pharmacology; Cell Membrane/drug effects/metabolism; Cell Nucleus/drug effects/metabolism; Cholesterol 7-alpha-Hydroxylase/antagonists & inhibitors/genetics; Enzyme Activation/drug effects; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors; Genetic/genetics; Hep G2 Cells; Hepatocyte Nuclear Factor 4/metabolism; Hepatocytes/*drug effects/enzymology/*metabolism; Humans; Intracellular Space/drug effects/metabolism; Ligands; Lithocholic Acid/*pharmacology; Mitogen-Activated Protein Kinase Kinases/metabolism; Phosphorylation/drug effects; Phosphotyrosine/metabolism; Promoter Regions; Protein Kinase Inhibitors/pharmacology; Protein Transport/drug effects; Proto-Oncogene Proteins c-raf/metabolism; Receptors; Retinoid X Receptor alpha/metabolism; Signal Transduction/*drug effects; src-Family Kinases/metabolism; Steroid Hydroxylases/genetics/metabolism; Vitamin D3 24-Hydroxylase

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

1151–1164

Issue

6

Volume

24

Citation

Han Shuxin; Li Tiangang; Ellis Ewa; Strom Stephen; Chiang John Y L, “A novel bile acid-activated vitamin D receptor signaling in human hepatocytes.,” NEOMED Bibliography Database, accessed April 19, 2021, https://neomed.omeka.net/items/show/4903.

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