The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.
Title
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.
Creator
Dluzen D E; McDermott J L
Publisher
Journal of neural transmission. General section
Date
1991
1991
Description
In the present experiment, male rats (15-17 months) were injected with deprenyl (0.25 mg/kg) three times per week for six months. At 21-23 months of age the male rats were sacrificed, the corpus striatum removed and superfused in vitro. Basal and evoked dopamine and DOPAC levels, as obtained with either two infusions of
Subject
Male; Animals; Rats; Corpus Striatum/*drug effects/metabolism; Aging/metabolism; In Vitro Techniques; Dopamine/*metabolism; Amphetamine/pharmacology; Levodopa/pharmacology; Selegiline/*pharmacology; 3; 4-Dihydroxyphenylacetic Acid/*metabolism
Identifier
Rights
Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).
Citation
Dluzen D E; McDermott J L, “The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.,” NEOMED Bibliography Database, accessed May 10, 2024, https://neomed.omeka.net/items/show/5372.