The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.

Title

The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.

Creator

Dluzen D E; McDermott J L

Publisher

Journal of neural transmission. General section

Date

1991
1991

Description

In the present experiment, male rats (15-17 months) were injected with deprenyl (0.25 mg/kg) three times per week for six months. At 21-23 months of age the male rats were sacrificed, the corpus striatum removed and superfused in vitro. Basal and evoked dopamine and DOPAC levels, as obtained with either two infusions of

Subject

Male; Animals; Rats; Corpus Striatum/*drug effects/metabolism; Aging/metabolism; In Vitro Techniques; Dopamine/*metabolism; Amphetamine/pharmacology; Levodopa/pharmacology; Selegiline/*pharmacology; 3; 4-Dihydroxyphenylacetic Acid/*metabolism

Identifier

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

145–156

Issue

2

Volume

85

Citation

Dluzen D E; McDermott J L, “The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.,” NEOMED Bibliography Database, accessed June 24, 2021, https://neomed.omeka.net/items/show/5372.

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