Browse Items (290 total)

Synaptic and neuronal loss are major neuropathological characteristics of Parkinson's disease. Misfolded protein aggregates in the form of Lewy bodies, comprised mainly of α-synuclein (αSyn), are associated with disease progression, and have also…

8. 5 RK JMS Formated_7.15 (45-47).pdf
The COVID-19 pandemic has affected patient access to healthcare in the field of dermatology. Due to efforts to minimize in-person healthcare visits, wait times for dermatology visits have increased, negatively affecting patients’ finances and…

9. 10 AP JMS Formated_7.15 (48-50).pdf
Commentary

7. 14 MD JMS Formated_7.15 (41-44).pdf
Prostate cancer is the second most commonly diagnosed form of cancer in men. While there are several treatment options for prostate cancer, robotic assisted laparoscopic prostatectomy is a customary option in the treatment of clinically localized…

11. 9 ND JMS Formated_7.15 (52).pdf
Overproduced reactive oxygen species (ROS) with decreased oxidative phosphorylation is a hallmark of the post-ischemic heart, which results in reperfusion-induced oxidative injury of the citric acid cycle (CAC). During ischemia, hypoxic conditions…

1. 2 AP TH JMS Formated_7.15 (1-5).pdf
Inconspicuous muscles in avian taxa have been previously discussed as vestigial remnants, however, evidence has shown that such muscles may hold a function in flight. Further investigations into inconspicuous muscles, such as M. coracotriceps, have…

2. 8 SM JMS Formated_7.15 (6-13).pdf
The COVID-19 pandemic has prompted the rise in the use of virtual healthcare through Telehealth. The importance of Telehealth is multi-fold, from communicating with patients virtually to providing care when in-person services are unavailable.…

3. 11 AP Wellness JMS Formatted_7.15 (14-26).pdf
Burnout is a syndrome of professional distress defined by symptoms of emotional exhaustion, depersonalization, and a sense of reduced personal accomplishment. Previous surveys (Wellness Surveys) at Northeast Ohio Medical University (NEOMED) seemed to…

10. 7 SM JMS Formated_7.15 (51).pdf
Letter to the Editor

9. 10 AP JMS Formated_7.15 (48-50).pdf
Commentary

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4. 3 KK JMS Formated_7.15 (27-31).pdf
This review aims to highlight two major health conditions that could benefit from regular supplementation of turmeric, as well as to discuss the importance of more widespread uses of this natural therapeutic in commonly used multivitamins and…

5. 4 JN JMS Formated_7.15 (32-37).pdf
Although COVID-19 is known primarily as a respiratory disease, infected patients have been known to experience COVID-19-associated coagulopathy from overactivation of immune response resulting in cytokine storm. As a fundamental principle of venous…

JMS 1st Edition August 2022 final.pdf
The Journal of Medical Sciences at NEOMED (JMS) is an online, student-led, peer-reviewed scholarly journal created to provide a platform for NEOMED students, faculty and affiliates to publish original research, opinion pieces, editorials, reviews,…

6. 1 VP Perera JMS Formated_7.15 (38-40).pdf
Mr. D, a 52-year-old male, was in an un-helmeted motorcycle collision with a concrete barrier resulting in polytrauma and traumatic brain injury. Mr. D was assessed by emergency services to be unresponsive with a Glasgow Coma Scale (GCS) of 13. He…

Eclampsia is a uniquely pregnancy-related disorder that manifests as a new onset of generalized tonic colonic seizures. It typically occurs after 20 weeks of concluded gestation, although it may occur sooner with plural gestations or molar…

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Twin births account for approximately 3% of live births and 97% of multiple bouts in the United States. In the absence of assisted reproductive technology, dizygotic twins are far more common than monozygotic twins and account for 70% of all twin…

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Induction of labor (IOL) is a common obstetric intervention that stimulates the onset of labor using artificial methods. Rates of labor induction have nearly doubled since 1990. There is substantial variation in IOL rates worldwide, and this can be…

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The superior colliculus is a paired structure in the rostral midbrain that is involved in incorporating environmental stimuli and coordinating gaze shifts involving both eye and head movements. It is known as the optic tectum in other vertebrates and…

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Mitochondrial reactive oxygen species (ROS) have emerged as an important mechanism of disease and redox signaling in the cellular system. Under basal or pathological conditions, electron leakage for ROS production is primarily mediated by complexes I…

The sinoatrial node (SA) is the default pacemaker and therefore a crucial component of the heart's conduction system. It is located subepicardially and is crescent in shape. The sinoatrial node is innervated by vagus and sympathetic nerves. The…

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Normal labor is characterized by regular and painful uterine contractions that conclude in progressive labor. A discussion on abnormal labor patterns is reviewed as abnormalities of the first stage (cervical dilation to complete cervical dilation)…

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Hemoglobin is an oxygen-binding protein found in erythrocytes that transports oxygen from the lungs to tissues. Each hemoglobin molecule is a tetramer made of four polypeptide globin chains. Each globin subunit contains a heme moiety formed of an…

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Background: Large immunogenomic analyses have demonstrated the prognostic role of the functional orientation of the tumor microenvironment in adult solid tumors, this variable has been poorly explored in the pediatric counterpart.

Methods: We…

Background and objectives: Observing biomarkers that affect alternative pathway dysregulation components may be effective in obtaining a new and more rapid diagnostic portrayal of atypical hemolytic uremic syndrome. We have conducted a systematic…

Normal labor is characterized by regular and painful uterine contractions that conclude in progressive labor. A discussion on abnormal labor patterns is reviewed as abnormalities of the first stage (cervical dilation to complete cervical dilation)…

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In the United States, trauma centers are identified through a designation process and a verification process. The criteria for the designation of a trauma center varies from state to state, and the designation process itself is the responsibility of…

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Complex Lymphatic Anomalies (CLA) are lymphatic malformations with idiopathic bone and soft tissue involvement. The extent of the abnormal lymphatic presentation and boney invasion varies between subtypes of CLA. The etiology of these diseases has…

The diversity, composition, and function of the bacterial community inhabiting the human gastrointestinal tract contributes to host health through its role in producing energy or signaling molecules that regulate metabolic and immunologic functions.…

The digastrics are a pair of muscles individually made up of two distinct muscle bellies: the anterior and posterior digastrics. They derive embryonically from the first and second pharyngeal arches. Together, they function in swallowing, chewing,…

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In 1995, the nuclear hormone orphan receptor farnesoid X receptor (FXR, NR1H4) was identified as a farnesol receptor expressed mainly in liver, kidney, and adrenal gland of rats. In 1999, bile acids were identified as endogenous FXR ligands.…

Background: Hyperparathyroid crisis (HPTC) is a potentially lethal condition characterized by severe symptomatic hypercalcemia with calcium levels ≥14 mg/dl. We sought to determine the rate of HPTC and how it differs from hyperparathyroidism (HPT)…

BACKGROUND Sarcoidosis is a systemic granulomatous disease of unknown cause, often affecting the lungs and lymphatic system. Neurologic manifestations of sarcoidosis, called "neurosarcoidosis", can present as cranial neuropathies and occur in an…

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Coronary microvascular dysfunction is prevalent among people with diabetes and is correlated with cardiac mortality. Compromised endothelial-dependent dilation (EDD) is an early event in the progression of diabetes, but its mechanisms remain…


Objectives: Aging is associated with sleep problems, which are common among assisted living (AL) residents. More than 40% of residents have insomnia, and almost 70% have a sleep disturbance of some kind. Melatonin to treat sleep disorders has…

Objective: To determine the Dynamin-related protein 1 (DRP1) regulation of mitochondrial fission in chondrocytes under pathological conditions, an area which is underexplored in osteoarthritis pathogenesis.

Design: DRP1 protein expression was…
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