Aging and neuropathic pain.

Title

Aging and neuropathic pain.

Creator

Novak J C; Lovell J A; Stuesse S L; Cruce W L; McBurney D L; Crisp T

Publisher

Brain research

Date

1999
1999-07

Description

Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve. The extent to which the aging process affects the thermal hyperalgesic responsiveness of these animals was investigated. The results demonstrate that the aging process differentially alters nociceptive processing.

Subject

Aging/*physiology; Animals; Hot Temperature; Hyperalgesia/*physiopathology; Ligation; Male; Nociceptors/physiology; Pain/*physiopathology; Peripheral Nervous System Diseases/physiopathology; Rats; Sciatic Nerve/injuries

Rights

Article information provided for research and reference use only. All rights are retained by the journal listed under publisher and/or the creator(s).

Pages

308–310

Issue

2

Volume

833

Citation

Novak J C; Lovell J A; Stuesse S L; Cruce W L; McBurney D L; Crisp T, “Aging and neuropathic pain.,” NEOMED Bibliography Database, accessed October 18, 2021, https://neomed.omeka.net/items/show/3841.

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