Browse Items (5 total)
- Tags: TGR5
Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation
Tags: 2018, 7alpha-hydroxy-4-cholesten-3-one, aminotransferase, aspartate-aminotransferase isozymes, BILE acids, Chibout S D, Couttet P, CYP7A1, Emotte C, Fairhurst R A, FGF19, fibroblast-growth-factor, Fischer A, Hepatocellular carcinoma, identification, induced liver-injury, Journal Article, Kinyamu-Akunda J, Klotho beta, Kluwe W, Kullak-Ublick G A, Lienard M, lipophilicity, Liver injury, Mahl J A, Manenti L, mitigation, Nuclear Receptor, Pognan F, Porta D G, Richardson T A, Schadt H S, Schwald M, serum, sinusoidal endothelial-cells, Skuba E, suppression, Teng C H, TGR5, Toxicological Sciences, Toxicology, Weiss A, Wolf A, Wuersch K
Bile acid receptors in non-alcoholic fatty liver disease.
Tags: 2013, Animals, Bile Acids and Salts/*metabolism, Biochemical pharmacology, Cholesterol, Cytoplasmic and Nuclear/agonists/*metabolism, Fatty Liver/drug therapy/immunology/*metabolism, FXR, G-Protein-Coupled/agonists/*metabolism, Glucose/metabolism, Humans, Inflammation, Jadhav Kavita, Li Yuanyuan, Lipid Metabolism/drug effects, Lipid Regulating Agents/chemistry/pharmacology/therapeutic use, Molecular Structure, Non-alcoholic Fatty Liver Disease, Receptors, TGR5, Triglyceride, Triglycerides/metabolism, Zhang Yanqiao
My lifelong dedication to bile acid research
Deficiency of both farnesoid X receptor and Takeda G protein-coupled receptor 5 exacerbated liver fibrosis in mice.
Circadian rhythms in liver metabolism and disease.
Tags: 2015, Acta pharmaceutica Sinica. B, ARC, arcuate nucleus, BMAL1, brain and muscle ARNT-like 1, CAR, Chiang John Y L, cholesterol 7alpha-hydroxylase, circadian locomotor output cycles kaput, Circadian Rhythm, CLOCK, constitutive androstane receptor, CRY, cryptochrome, CYP7A1, CYPs, cytochrome P450 enzymes, D-site binding protein, DBP, Department of Integrative Medical Sciences, E-box, emergency medical technician, EMT, enhance box, FAA, familial advanced sleep-phase syndrome, farnesoid-X receptor, FASPS, FEO, Ferrell Jessica M, food anticipatory activity, food entrainable oscillator, forkhead box O3, FOXO3, FXR, G protein-coupled bile acid receptor, glucose transporter 2, GLUT2, HDAC3, hepatic leukemia factor, Hip, histone deacetylase 3, HLF, hypoxia inducing protein, LDL, Liver, liver receptor homolog 1, Low-density lipoprotein, LRH1, Metabolic syndrome, NAD+, NEOMED College of Medicine, nicotinamide adenine dinucleotide, PER, period, retinohypothalamic tract, retinoid-related orphan receptor alpha, RHT, ROR-response element, RORalpha, RORE, SCN, SHP, SIRT1, sirtuin 1, small heterodimer partner, suprachiasmatic nucleus, TEF, TGR5, thyrotroph embryonic factor, transcriptional translational feedback loop, TTFL, Type 2 diabetes