Sarcoidosis is a disease of unknown etiology which is characterized pathologically by widespread noncaseating granulomas involving multiple organ systems. We report a case of sarcoidosis presenting as a ventilation-perfusion mismatch on a lung scan.
A recombinant baculovirus containing the human CYP3A4 cDNA was constructed and used to express CYP3A4 in SF9 insect cells (0.46 +/- 0.13 nmol/mg protein, 103 +/- 29 nmol/liter, N = 15). The enzyme represented similar to 2-3% of total cellular protein…
Medical waste appears, on the surface, to be dangerous. Public perception of medical waste is, in general, inaccurate. After syringes washed up on the beaches of New York and New Jersey in the summers of 1987 and 1988, and fanned by the…
A review of The Career Development Quarterly was conducted for a 20-year period (Volumes 23 through 42). A total of 791 articles were classified into the 14 substantive areas of career research and practice devised by Fitzgerald and Rounds (1989).…
Few reports in gynecologic literature have addressed patient preferences about terminal care. In light of the current discussions about end-of-life decision-making, a study was designed to assess the desires of patients with gynecologic cancer. A…
We describe a normal pregnancy that was conceived less than 3 weeks following curettage for a blighted ovum. A delay between curettage and subsequent pregnancy is often recommended. Evidence supporting such a delay is examined.
Only two cases of beta(2)-microglobulin amyloid tumors involving the buttocks have been reported in the world literature. We report a case of bilateral buttock amyloid tumors with associated carpal tunnel syndrome and pathologic fracture involving…
Ampicillin/sulbactam (1.0-2.0 g ampicillin and 0.5-1.0 g sulbactam) and cefoxitin (1.0-2.0 g), both administered intravenously once every 6 hours, were compared in patients with lower respiratory tract infections. Thirty-two of the 51…
The complex interaction between plasma and tissue concentrations of drug has significant implications for therapies that use beta-lactam antibiotics. This comparative, triple-crossover, open-label study enrolled 12 healthy adult male volunteers to…
Objectives: Deactivation of endothelium-derived relaxing factor due to an increased oxygen radical load during sepsis may contribute to an impairment in microcirculatory blood flow. We investigated whether treatment with the sulfhydryl donor and…
Noting the common occurrence of arthritis in contemporary elephants, a skeletal study was undertaken to assess the frequency and nature of the affliction. Spondyloarthropathy was unequivocally diagnosed in mammoths (Mammuthus primigenius) and…
The etiology of arthritis in Hyaenidae has been a subject of conjecture. While osteoarthritis has been considered, the observation of an erosive arthritis prompted a systematic survey of museum specimens to define its nature and frequency.…
The relationship between social ties, stage of disease, and survival was analyzed in a population-based sample of 525 black and 486 white women with newly diagnosed breast cancer. There were significant differences between the two race groups in…
We describe a unilateral loss of vision caused by central retinal artery occlusion in a patient with alcoholic hepatitis. An extensive search to define the source of emboli or vasculitides as a cause for central retinal artery occlusion was…
Background: The clinical diagnosis of infective endocarditis due to Staphylococcus aureus can be difficult, and many patients with this disease are only diagnosed post mortem. There are few published reports of large series of patients with S aureus…
Patients with Proteus mirabilis bacteremia at a large community teaching hospital during a 13-year period (1980-1992) were retrospectively reviewed. There were 176 patients whereof 44 (25%) had polymicrobial bacteremia. The median age of patients was…
Escherichia coli seldom causes pneumonia. In 1967 Tillotson and Lerner [1] reported 20 cases of pneumonia caused by E. coli. They concluded that E. coli pneumonia generally followed bacteremia seeded from acute or chronic infections of the…
