Diabetes, a syndrome characterized by high plasma glucose and low plasma insulin concentrations, is associated with somatic and autonomic neuropadiabetes as well as cardiac and vascular disorders. These consequences of diabetes significantly affect…
Recently, we were charged with providing a learning opportunity for high school students participating in the Upward Bound Regional Math and Science Program, a program designed to stimulate interest in mathematics and science for students from…
We wanted a new and innovative method of engaging students in interactive learning. To this end, we developed an educational tool that compares and contracts the cardiopulmonary responses to exercise in an individual with heart failure with an…
Dynamic exercise may be used as a safe, therapeutic approach to reduce sympathetic nerve activity at rest and thus may be beneficial for individuals with hypertension. Therefore, we tested the hypothesis that a single bout of mild to moderate dynamic…
The influence of daily spontaneous running (DSR) and gender on postexercise cardiac autonomic responses was examined in spontaneously hypertensive rats. Rats were weaned at 4-5 wk of age and were randomly assigned to a sedentary (7 males and 6…
Exercise training attenuates arterial baroreflex function. Mechanisms responsible may include an attenuated aortic baroreceptor reactivity (afferent mechanisms) and/or an attenuated central baroreflex gain. We tested the hypothesis that the aortic…
We tested the hypothesis that the reflex inhibition of heart rate (HR) during mechanical (acute bolus injection of 0.5% and 2% of estimated blood volume) and chemical (phenylbiguanide, PBG, 2.5 and 5 micrograms.kg-1) stimulation of cardiopulmonary…
The influence of daily spontaneous running (DSR) and gender on the arterial baroreflex regulation of heart rate (HR) and lumbar sympathetic nerve activity (LSNA) was examined in 13 male [7 sedentary (SED) and 6 DSR] and 12 female (6 SED and 6 DSR)…
Arterial pressure (AP), heart rate (HR), cardiac sympathetic tonus (ST), and parasympathetic tonus (PT) were determined in spontaneously hypertensive rats (SHR, 8 male and 8 female) and Wistar-Kyoto normotensive rats (WKY, 8 male and 12 female)…
Arterial pressure, cardiac sympathetic tonus (ST), and heart rate (HR) are reduced after a single bout of dynamic exercise in spontaneously hypertensive rats (SHR). To test if the arterial baroreflex is required for these postexercise responses,…
Normal aging is associated with cardiac, vascular, and pulmonary adaptations that significantly affect the individual's ability to maintain homeostasis. To understand the changes associated with aging, we developed a laboratory exercise that compares…
We wanted to develop educational materials appropriate for the high school student which would present physiological concepts in an innovative way. The impetus was in response to the lack of physiology educational materials appropriate for the high…
Employment opportunities in the future will require higher skills and an understanding of mathematics and science. As a result of the growing number of careers that require solid science and mathematics training, the methods of science education are…
