Deep venous thrombosis (DVT) of the upper extremity has recently been recognized as being more common than previously reported (probably because of the increasingly frequent use of subclavian venous access). A retrospective review of patients in whom…
As the number of elderly persons in the United States continues to increase, geriatric abuse has become the most recent manifestation of domestic violence seen in the emergency department. Recent data suggest that 1 million elderly persons are…
Continuous measurement of arterial oxygen saturation (SaO2) using pulse oximetry has become a common monitoring and management technique in critically ill hospitalized patients. To determine the impact of SaO2 monitoring on emergency patient…
The effects of thiamine thiazolone (TT) and thiamine thiazolone pyrophosphate (TTPP) on the in vitro and in vivo inhibition of pyruvate dehydrogenase complex (PDHC) from rat cortex and hippocampus were characterized. TTPP decreased PDHC activity in…
The correct timing of surgery in cases of gallstone pancreatitis is debatable. To delineate more clearly the influence of the timing of surgery in the treatment of the disease, a prospective randomized clinical study of early surgery (less than 48…
A peculiar dynamic in communication exists between those who are most likely to be involved in life-prolongation decisions. We found that both the elderly and health care professionals talk about life-prolongation, but not with one another; that they…
Alkaline phosphatase isoenzyme determination (APID) is in common use despite evidence suggesting that the results correlate poorly with actual sites of disease. To assess the predictive value of this test in clinical practice, 99 APIDs performed on…
We tested the hypothesis that the vasoconstriction produced by the application of blood to the adventitial surfaces of the vessels of an isolated perfused canine circle of Willis preparation was mediated by products of prostaglandin metabolism. In…
Male rats were trained to discriminate the stimulus effects of CGS 9896 (30.0 mg/kg) from its vehicle. Once trained, discriminative performance was observed to be dose-responsive in the 3.75-30.0 mg/kg range and analysis of the dose-response curve…
We evaluated the ability of a group of male runners (n = 4) to do maximal and submaximal exercise before and after they ran a competitive marathon (42.2 km) race. VO2max was determined 3 to 6 times in each runner, on alternate days, 1-4 weeks prior…
The solvent drag reflection coefficient (sigma) for total proteins can be estimated by comparing the relative degrees of concentration of erythrocytes and plasma proteins that occur during fluid filtration in an isolated perfused organ. In this…
Previous studies have suggested that papaverine, a drug commonly used in studies of transvascular fluid and solute exchange to eliminate confounding effects of changes in vascular tone, may itself increase vascular permeability. In this study, we…
A transcatheter technique of removing a detached angioplasty guidewire segment from the diagonal branch of the left anterior descending coronary artery is described. A standard 0.014 angioplasty guidewire was modified into a "snare" apparatus for…
