Browse Items · NEOMED Bibliography Database

Early physiological and cellular indicators of cisplatin-induced ototoxicity.

Cisplatin chemotherapy often causes permanent hearing loss, which leads to a multifaceted decrease in quality of life. Identification of early cisplatin-induced cochlear damage would greatly improve clinical diagnosis and provide potential drug…

Tags: 2021, cisplatin, Hair Cells, Ototoxicity, Schwann cell, Spiral ganglion neuron

Conductive hearing loss during development does not appreciably alter the sharpness of cochlear tuning.

An increasing number of studies show that listeners often have difficulty hearing in situations with background noise, despite normal tuning curves in quiet. One potential source of this difficulty could be sensorineural changes in the auditory …

Tags: 2021, Auditory Pathways, conductive hearing loss, Department of Anatomy & Neurobiology, Hair Cells, Ihlefeld A, journalArticle, March 2021 List, NEOMED College of Medicine, NEOMED Postdoc Publications, Rosen MJ, Scientific reports, SENSORINEURAL hearing loss, Signal-To-Noise Ratio, Ye Y

Early physiological and cellular indicators of cisplatin-induced ototoxicity.

Cisplatin chemotherapy often causes permanent hearing loss, which leads to a multifaceted decrease in quality of life. Identification of early cisplatin-induced cochlear damage would greatly improve clinical diagnosis and provide potential drug …

Tags: 2021, Bao J, Bielefeld EC, Chen Y, cisplatin, Department of Anatomy & Neurobiology, Hair Cells, January 2021 List, Journal of the Association for Research in Otolaryngology : JARO, journalArticle, Mafi Amir M, Mellott JG, NEOMED College of Medicine, Ototoxicity, Schwann cell, Spiral ganglion neuron, Wang W, Yamoah EN

Specific And Efficient Transduction Of Cochlear Inner Hair Cells With Recombinant Adeno-associated Virus Type 3 Vector

Recombinant adeno-associated virus (AAV) vectors are of interest for cochlear gene therapy because of their ability to mediate the efficient transfer and long-term stable expression of therapeutic genes in a wide variety of postmitotic tissues with…

Noise-induced cochlear synaptopathy: Past findings and future studies.

For decades, we have presumed the death of hair cells and spiral ganglion neurons are the main cause of hearing loss and difficulties understanding speech in noise, but new findings suggest synapse loss may be the key contributor. Specifically,…

Canertinib induces ototoxicity in three preclinical models.

Neuregulin-1 (NRG1) ligand and its epidermal growth factor receptor (EGFR)/ERBB family regulate normal cellular proliferation and differentiation in many tissues including the cochlea. Aberrant NRG1 and ERBB signaling cause significant hearing…

Otoprotective Effects of Stephania tetrandra S. Moore Herb Isolate against Acoustic Trauma.

Noise is the most common occupational and environmental hazard, and noise-induced hearing loss (NIHL) is the second most common form of sensorineural hearing deficit. Although therapeutics that target the free-radical pathway have shown promise, none…

Browse Items (7 total)

Early physiological and cellular indicators of cisplatin-induced ototoxicity.

Conductive hearing loss during development does not appreciably alter the sharpness of cochlear tuning.

Early physiological and cellular indicators of cisplatin-induced ototoxicity.

Specific And Efficient Transduction Of Cochlear Inner Hair Cells With Recombinant Adeno-associated Virus Type 3 Vector

Noise-induced cochlear synaptopathy: Past findings and future studies.

Canertinib induces ototoxicity in three preclinical models.

Otoprotective Effects of Stephania tetrandra S. Moore Herb Isolate against Acoustic Trauma.