Browse Items (6 total)
- Tags: CYP7A1
Circadian rhythms in liver metabolism and disease.
Tags: 2015, Acta pharmaceutica Sinica. B, ARC, arcuate nucleus, BMAL1, brain and muscle ARNT-like 1, CAR, Chiang John Y L, cholesterol 7alpha-hydroxylase, circadian locomotor output cycles kaput, Circadian Rhythm, CLOCK, constitutive androstane receptor, CRY, cryptochrome, CYP7A1, CYPs, cytochrome P450 enzymes, D-site binding protein, DBP, Department of Integrative Medical Sciences, E-box, emergency medical technician, EMT, enhance box, FAA, familial advanced sleep-phase syndrome, farnesoid-X receptor, FASPS, FEO, Ferrell Jessica M, food anticipatory activity, food entrainable oscillator, forkhead box O3, FOXO3, FXR, G protein-coupled bile acid receptor, glucose transporter 2, GLUT2, HDAC3, hepatic leukemia factor, Hip, histone deacetylase 3, HLF, hypoxia inducing protein, LDL, Liver, liver receptor homolog 1, Low-density lipoprotein, LRH1, Metabolic syndrome, NAD+, NEOMED College of Medicine, nicotinamide adenine dinucleotide, PER, period, retinohypothalamic tract, retinoid-related orphan receptor alpha, RHT, ROR-response element, RORalpha, RORE, SCN, SHP, SIRT1, sirtuin 1, small heterodimer partner, suprachiasmatic nucleus, TEF, TGR5, thyrotroph embryonic factor, transcriptional translational feedback loop, TTFL, Type 2 diabetes
My lifelong dedication to bile acid research
Bile acid signaling in lipid metabolism: metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.
Tags: 2015, Animals, Bile acid metabolism, Bile Acids and Salts/genetics/*metabolism, Biochimica et biophysica acta, Cheng Jie, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/genetics/metabolism, CYP7A1, Department of Integrative Medical Sciences, Diabetes Mellitus/genetics/*metabolism, Diet, farnesoid X receptor (FXR), Female, Ferrell Jessica M, Glucose/genetics/metabolism, Gonzalez Frank J, High-Fat/methods, Homeostasis, Inbred C57BL, Insulin Resistance, Intestinal Mucosa/metabolism, Jiang Changtao, Krausz Kristopher W, Li Tiangang, Lipid Metabolism/*physiology, lipidomics, Liver/metabolism, Male, Metabolome/*genetics, Metabolomics/methods, Mice, NEOMED College of Medicine, Obesity/genetics/*metabolism, Qi Yunpeng, Rats, Signal Transduction, tauro-beta-muricholic acid, Taurocholic Acid/analogs & derivatives/genetics/metabolism, Transgenic
Bile Acid Sequestration by Cholestyramine Mitigates FGFR4 Inhibition-Induced ALT Elevation
Tags: 2018, 7alpha-hydroxy-4-cholesten-3-one, aminotransferase, aspartate-aminotransferase isozymes, BILE acids, Chibout S D, Couttet P, CYP7A1, Emotte C, Fairhurst R A, FGF19, fibroblast-growth-factor, Fischer A, Hepatocellular carcinoma, identification, induced liver-injury, Journal Article, Kinyamu-Akunda J, Klotho beta, Kluwe W, Kullak-Ublick G A, Lienard M, lipophilicity, Liver injury, Mahl J A, Manenti L, mitigation, Nuclear Receptor, Pognan F, Porta D G, Richardson T A, Schadt H S, Schwald M, serum, sinusoidal endothelial-cells, Skuba E, suppression, Teng C H, TGR5, Toxicological Sciences, Toxicology, Weiss A, Wolf A, Wuersch K
Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a
Tags: 2017, 4EBP-1, ACAT, acyl-CoA:cholesterol acyltransferase, CE, Cellular and molecular gastroenterology and hepatology, Chavan Hemantkumar, Chiang John Y L, chloroquine, Cholesterol, cholesterol 7alpha-hydroxylase, cholesterol ester, Cholestyramine, ChTM, CQ, CYP7A1, Department of Integrative Medical Sciences, diet-induced obesity, Ding Wen-Xing, Ding Yifeng, DIO, endoplasmic reticulum, ER, eukaryotic translation initiation factor 4E-binding protein 1, Fatty Liver, FC, free cholesterol, glycogen synthase kinase 3beta, GSK3beta, HMG-CoA reductase, HMGCR, Krishnamurthy Partha, LC3, LDLR, Li Jibiao, Li Tiangang, LMP, low-density lipoprotein receptor, lysosome membrane permeabilization, Matye David, messenger RNA, microtubule-associated protein 1A/1B-light chain 3, mRNA, mTOR, NEOMED College of Medicine, Ni Hong-Min, Nuclear Receptor, phosphatidylinositol, PI, plasma membrane, PM, S6, SREBP, sterol response element binding protein, the nutrient sensing mechanistic target of rapamycin, tibosomal protein S6, Wang Yifeng
On the mechanism of bile acid inhibition of rat sterol 12 alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4 alpha
Tags: 2002, activation, bile acid synthesise, Biochemistry & Molecular Biology, Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, Biophysics, biosynthesis, Cell Biology, Chiang J Y L, cholesterol 7-alpha-hydroxylase gene, CYP7A1, cytochrome P450, Eggertsen G, expression, feedback-regulation, Gene Regulation, Journal Article, liver microsomal metabolism, Nuclear Receptor, promoter, Receptor, repression, Yang Y Z, Zhang M