Browse Items (4 total)
- Tags: Ge Xuemei
Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis.
Tags: *Homeostasis, *Lipid Metabolism, 2014, Adorini Luciano, Animals, Carboxylic Ester Hydrolases/*physiology, Chen Wei-Dong, Cholesterol/blood, Cytoplasmic and Nuclear/*physiology, Department of Integrative Medical Sciences, Fatty Acids/metabolism, Ge Xuemei, Hepatology (Baltimore, Md.), Inbred C57BL, Jadhav Kavita, Li Yuanyuan, Lipogenesis, Liver/*enzymology, Mice, NEOMED College of Medicine, Receptors, Sterol Regulatory Element Binding Protein 1/physiology, Triglycerides/metabolism, Xu Jiesi, Xu Yang, Yin Liya, Zhang Yanqiao
Hepatic hepatocyte nuclear factor 4alpha is essential for maintaining triglyceride and cholesterol homeostasis.
Tags: 2011, Adenoviridae/genetics, Animal, Animals, Arteriosclerosis, thrombosis, and vascular biology, Cells, Cholesterol, Cholesterol/*metabolism, Cultured, Department of Integrative Medical Sciences, Edwards Peter A, Fatty Liver/metabolism/physiopathology, Ge Xuemei, HDL/metabolism, Hepatocyte Nuclear Factor 4/drug effects/genetics/*physiology, Hepatocytes/cytology/*metabolism, Homeostasis/genetics/*physiology, Inbred C57BL, Lipid Metabolism/genetics/physiology, Ma Huiyan, Mice, Models, NEOMED College of Medicine, RNA, Small Interfering/genetics/pharmacology, Triglycerides/*metabolism, VLDL/metabolism, Yin Liya, Zhang Yanqiao
Tags: *Aldehyde Reductase/genetics/metabolism, 2011, Adenoviridae, Animal, Animals, Blood Glucose/*metabolism, Chiang John Y L, Cholesterol/analysis, Cytoplasmic and Nuclear/genetics/*metabolism, Department of Integrative Medical Sciences, Diabetes Mellitus/genetics/*metabolism/physiopathology, Disease Models, Fatty Liver/genetics/*metabolism/physiopathology, Ge Xuemei, Gene Expression, Genetic Vectors, Gluconeogenesis/genetics, Homeostasis, Humans, Journal of lipid research, Li Tiangang, Liver/*metabolism/physiopathology, Ma Huiyan, Malondialdehyde/blood, Mice, NEOMED College of Medicine, Polymerase Chain Reaction, Receptors, Transfection, Transgenic, Triglycerides/analysis, Yin Liya, Zhang Yanqiao
Loss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.
Tags: 2012, Adipose Tissue, Adiposity/genetics, Animals, Brown/pathology, Carcinoma/etiology/*genetics, Cell Transformation, Chen Wei-Dong, Cytoplasmic and Nuclear/*deficiency/genetics, Diet, Dietary Fats/metabolism, Edwards Peter A, Energy Metabolism/genetics, Female, Ge Xuemei, Gene Knockout Techniques, Glucose Intolerance/complications/genetics, Heemstra Lydia A, High-Fat/*adverse effects, Intestinal Absorption, Kasim Neda, Knockout, Leptin/deficiency/genetics, Liver Neoplasms/etiology/*genetics, Liver/pathology, Ma Huiyan, Male, Mice, Molecular endocrinology (Baltimore, Md.), Muscle, Neoplastic/genetics, Novak Colleen M, Obese, Obesity/*etiology/genetics, Receptors, Sex Factors, Skeletal/metabolism, Smith Joseph L, Weight Gain/genetics, Xu Jiesi, Zhang Yanqiao