Browse Items · NEOMED Bibliography Database

Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

The efficacy of a new pharmacokinetically enhanced formulation of amoxycillin/clavulanate (AMX/CA) 2000/125 mg, twice daily, designed to provide adequate levels of amoxycillin over the 12-h dosing interval to eradicate penicillin-resistant…

Tags: *Treatment Outcome, 2002, 80 and over, Adolescent, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination/administration & dosage/*pharmacokinetics/pharmacology/*therapeutic use, Amoxicillin/adverse effects/therapeutic use, Bacterial, Bacterial/drug therapy/immunology, Bronchitis/drug therapy/microbiology, Combination/adverse effects/*therapeutic use, Department of Internal Medicine, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Drug Therapy, Female, File Thomas M Jr, Follow-Up Studies, Humans, International journal of antimicrobial agents, Jacobs Michael R, Male, Microbial Sensitivity Tests, Middle Aged, Multicenter Studies as Topic, NEOMED College of Medicine, Pneumonia, Poole Michael D, Respiratory Tract Infections/*drug therapy/metabolism/microbiology, Streptococcal Infections/*drug therapy/metabolism/microbiology, Streptococcus pneumoniae/*drug effects, Wynne Brian

Overview of resistance in the 1990s.

The tremendous therapeutic advantage afforded by antibiotics is being threatened by the emergence of increasingly resistant strains of microbes. Selective pressure favoring resistant strains arises from misuse and overuse of antimicrobials (notably…

Tags: *Drug Resistance, 1999, Anti-Bacterial Agents/*therapeutic use, Bacterial/*drug therapy, Chest, Community-Acquired Infections/drug therapy, Cross Infection/drug therapy, Department of Internal Medicine, File T M Jr, Humans, Multiple, NEOMED College of Medicine, Pneumonia

Pediatric airway management in COVID-19 patients: consensus guidelines from the society for pediatric anesthesia's pediatric difficult intubation collaborative and the Canadian Pediatric Anesthesia Society.

The severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) pandemic has challenged medical systems and clinicians globally to unforeseen levels. Rapid spread of COVID-19 has forced clinicians to care for patients with a…

Tags: 2020, Adolescent, Airway Management/ methods, Anesthesia and Analgesia, Anesthesia/methods, Anesthesiology/ methods/standards, Asaf S, Ayad I, Bhalla T, Castro P, Chiao F, Child, Consensus, Coronavirus Infections/ therapy, Crockett C, Dalesio N, Denning S, Department of General Surgery, Disma N, Engelhardt T, Evans F, Fiadjoe JE, Galvez I, Gálvez J, Garcia-Marcinkiewicz A, Glover C, Gooden C, Greenberg R, Greenwood E, Guidelines as Topic, Gumaney H, Haydar B, Hervías M, Hsu G, Humans, Hunyady A, Infant, Infection Control, Infectious Disease Transmission, Ingelmo P, Intratracheal/ methods/standards, Intubation, Jagannathan N, Javia L, journalArticle, July 2020 List, Kiss EE, Kovatsis PG, Lardner D, Lau J, Lee JK, Lee LK, Lockman JL, Matava CT, Matuszczak M, McCloskey J, Mireles S, NEOMED College of Medicine, Newborn, Olomu P, Pandemics, Park R, Patient-to-Professional/prevention & control, Pediatrics/ methods/standards, Pérez-Pradilla C, Peyton J, Pneumonia, Polaner D, Preschool, Raman VT, Rehman M, Reynolds P, Sabato S, Stein ML, Szmuk P, Szolnoki J, Taicher B, Tan J, Templeton T, Theroux MC, Thompson N, Viral/ therapy, Von Ungern-Sternberg B, Whyte S, Yaster M, Yu J

Pneumococcal epidemiology among us adults hospitalized for community-acquired pneumonia

BACKGROUND: Few studies have measured the burden of adult pneumococcal disease after the introduction of 13-valent pneumococcal conjugate vaccine (PCV13) into the US infant vaccination schedule. Further, most data regarding pneumococcal serotypes are…

Pre-pharyngeal Swallow Effects of Recurrent Laryngeal Nerve Lesion on Bolus Shape and Airway Protection in an Infant Pig Model.

Recurrent laryngeal nerve (RLN) damage in infants leads to increased dysphagia and aspiration pneumonia. Recent work has shown that intraoral transport and swallow kinematics change following RLN lesion, suggesting potential changes in bolus…

Predictors of mortality for nursing home-acquired pneumonia: a systematic review.

BACKGROUND: Current risk stratification tools, primarily used for CAP, are suboptimal in predicting nursing home acquired pneumonia (NHAP) outcome and mortality. We conducted a systematic review to evaluate current evidence on the usefulness of…

Rapid Detection Of Streptococcus Pneumoniae In Community-acquired Pneumonia

Tags: 2006, adults, antimicrobial therapy, bacteremic pneumococcal pneumonia, cerebrospinal-fluid, Clinical Microbiology and Infection, Diagnosis, File T M, Infections, Infectious Diseases, Kozlov R S, Management, Microbiology, Pneumococcus, Pneumonia, polymerase chain-reaction, rapid detection, sputum culture, urinary antigen test

Recommendations for treatment of hospital-acquired and ventilator-associated pneumonia: review of recent international guidelines.

Recently published guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia are reviewed for recommendations regarding diagnosis and antimicrobial therapy to assess the implications for development of future…

Tags: *Practice Guidelines as Topic, 2010, Anti-Bacterial Agents/*therapeutic use, Bacteria/drug effects/isolation & purification, Bacterial/diagnosis/*drug therapy, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Clinical Trials as Topic, Cross Infection/diagnosis/*drug therapy, Department of Internal Medicine, File Thomas M Jr, Hospitals, Humans, Microbial Sensitivity Tests, NEOMED College of Medicine, Pneumonia, Time Factors, Ventilator-Associated/diagnosis/*drug therapy

Respiratory infections unique to Asia

Asia is a highly heterogeneous region with vastly different cultures, social constitutions and populations affected by a wide spectrum of respiratory diseases caused by tropical pathogens. Asian patients with community-acquired pneumonia differ from…

Role of 'atypical' pneumonia pathogens in respiratory tract infections.

The 'atypical' pathogens are important causes of pneumonia, causing illness ranging from mild to life-threatening. The most common atypical pathogens are Mycoplasma pneumoniae and Chlamydia pneumoniae; others include Legionella species, Chlamydia…

Tags: 1999, Bacterial/diagnosis/*microbiology, Canadian respiratory journal, Chlamydia Infections, Chlamydophila pneumoniae, Community-Acquired Infections, Humans, Immunoenzyme Techniques, Legionella pneumophila, Mycoplasma/diagnosis/*microbiology, Pneumonia, Polymerase Chain Reaction, Tan J S

Serum Concentrations of Aerosolized Tobramycin in Medical, Surgical, and Trauma Patients

Tags: 2009, Antimicrobial agents and chemotherapy, Beam W B, Burdette S D, Journal Article or Conference Abstract Publication, Limkemann A J, Markert R J, Microbiology, Pharmacology & Pharmacy, Pneumonia, Slaughter J B

SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.

BACKGROUND: Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. METHODS: A total of 863 adults with…

Tags: *clinical trial, *Community-acquired, *Pneumonia, *solithromycin, *Streptococcus pneumoniae, 2016, 80 and over, Administration, Adult, Aged, Anti-Bacterial Agents/*administration & dosage/adverse effects, Bacterial, Bacterial/diagnosis/*drug therapy/*microbiology, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/diagnosis/*drug therapy/*microbiology, Comorbidity, Das Anita F, Department of Internal Medicine, Drug Resistance, Female, Fernandes Prabhavathi, File Thomas M Jr, Fluoroquinolones/*administration & dosage/adverse effects, Gonong Joven Roque V, Humans, Intravenous, Jamieson Brian D, Keedy Kara, Macrolides/*administration & dosage/adverse effects, Male, Microbial Sensitivity Tests, Middle Aged, Moxifloxacin, NEOMED College of Medicine, Oldach David, Oral, Pneumonia, Rewerska Barbara, Sheets Amanda, Taylor David, Treatment Outcome, Triazoles/*administration & dosage/adverse effects, Vucinic-Mihailovic Violeta

Spectrum of excess mortality due to carbapenem-resistant Klebsiella pneumoniae infections.

Patients infected or colonized with carbapenem-resistant Klebsiella pneumoniae (CRKp) are often chronically and acutely ill, which results in substantial mortality unrelated to infection. Therefore, estimating excess mortality due to CRKp infections…

Tags: *beta-Lactam Resistance, 2016, 80 and over, Aged, Bacteremia/microbiology/mortality, Bacterial/microbiology/mortality, Bonomo R A, carbapenem-resistant Enterobacteriaceae, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, Cober E, Department of Internal Medicine, Doi Y, Epidemiology, Evans S, Female, Fowler V G Jr, Hauck C, Humans, Kalayjian R C, Kaye K S, Klebsiella Infections/*microbiology/*mortality, Klebsiella pneumoniae, Klebsiella pneumoniae/*drug effects/isolation & purification, Longitudinal Studies, Male, Middle Aged, Mortality, NEOMED College of Medicine, Perez F, Pneumonia, Prospective Studies, Richter S S, Salata R A, Scalera N M, Survival Analysis, Urinary Tract Infections/microbiology/mortality, van Duin D, Watkins R R

Strategies for improving antimicrobial use and the role of antimicrobial stewardship programs.

Subglottic Secretion Suctioning Reduces Vent-Associated Pneumonia, Antibiotic Use.

Tags: 2014, Academic Medical Centers, Antibiotics, Belgium, Confidence Intervals, Department of Internal Medicine, Endotracheal – Utilization, Human, Infectious Disease Alert, NEOMED College of Medicine, Odds Ratio, Pneumonia, RANDOMIZED controlled trials, Secretions, Suctioning, Ventilator-Associated – Prevention and Control, Watkins Richard R

Summary of ceftaroline fosamil clinical trial studies and clinical safety.

In October 2010, the new cephalosporin, ceftaroline fosamil, was approved by the US Food and Drug Administration for therapy of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSIs). The active…

Tags: 2012, Anti-Bacterial Agents/adverse effects/*therapeutic use, Bacterial/drug therapy, Cephalosporins/adverse effects/*therapeutic use, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Clinical Trials as Topic, Department of Internal Medicine, File Thomas M Jr, Humans, NEOMED College of Medicine, Pneumonia, Staphylococcal Skin Infections/drug therapy, Stein Gary E, Wilcox Mark H

The Effect Of Bilateral Superior Laryngeal Nerve Lesion On Swallowing: A Novel Method To Quantitate Aspirated Volume And Pharyngeal Threshold In Videofluoroscopy

The Importance Of Chlamydia Pneumoniae As A Pathogen: The 1996 Consensus Conference On Chlamydia Pneumoniae Infections

The relationship between psychiatric medication and course of hospital stay among intoxicated trauma patients

Introduction The purpose of this study was to determine whether trauma patients requiring psychiatric medication who were admitted with positive alcohol or drug screen require more pain medications or sedation resulting in longer length of stay.…

The role of atypical pathogens: Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila in respiratory infection.

Infections caused by M. pneumoniae, C. pneumoniae, and Legionella spp. are important causes of community-acquired pneumonia (CAP). In the past decade, considerable new information has come to light concerning these organisms. Despite this, debate…

The Science of Selecting Antimicrobials for Community-Acquired Pneumonia (CAP)

The science of selecting antimicrobials for community-acquired pneumonia (CAP).

BACKGROUND: Among infectious diseases, community-acquired pneumonia (CAP) is the leading cause of death in the United States and is associated with a substantial economic burden to the health care system. Initiating appropriate empiric therapy can be…

Treating CAP caused by penicillin-resistant S pneumoniae.

Over the last decade, the incidence of penicillin resistance among Streptococcus pneumoniae isolates has markedly increased. This trend is unsettling because infections caused by S pneumoniae are among the leading causes of morbidity and mortality in…

Tags: 1999, Bacterial, Bacterial – Diagnosis, Community-Acquired Infections, Department of Internal Medicine, Diagnosis, Differential, Drug Resistance, File T M Jr, Journal of Respiratory Diseases, Microbial, NEOMED College of Medicine, Pneumonia, Streptococcal Infections

Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies

Background Community-acquired pneumonia (CAP) guidelines have improved the treatment and outcomes of patients with CAP, primarily by standardization of initial empirical therapy. But current society-published guidelines exclude immunocompromised…

Ventilator-associated pneumonia: gearing towards shorter-course therapy

Purpose of review The studies that are reviewed in this article have all concluded that a shorter duration of antibiotic therapy (7-8 days) may be adequate in the treatment of the majority of patients with ventilator-associated pneumonia, and does…

Tags: 2006, antibiotic-therapy, antimicrobial therapy, Chua T D, Current opinion in infectious diseases, duration of therapy, File T M, Infection, Infectious Diseases, Journal Article or Conference Abstract Publication, Pneumonia, pseudomonas-aeruginosa, resolution, trial, ventilator-associated

What can we learn from the time course of untreated and partially treated community-onset Streptococcus pneumoniae pneumonia? A clinical perspective on superiority and noninferiority trial designs for mild community-acquired pneumonia.

There are no well-designed placebo-controlled clinical trials in the recent era that precisely define the magnitude of the drug effect of antimicrobial therapy for mild community-acquired pneumonia (CAP). However, there is evidence that ineffective…

Tags: *Research Design, 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/*drug therapy/microbiology, Department of Internal Medicine, Disease Progression, File Thomas M Jr, Humans, NEOMED College of Medicine, Pneumococcal/*drug therapy/microbiology, Pneumonia, Randomized Controlled Trials as Topic/*methods, Schentag Jerome J, Streptococcus pneumoniae/*isolation & purification, Time Factors, Treatment Outcome

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