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Testosterone relaxes coronary arteries by opening the large-conductance, calcium-activated potassium channel

Cardiovascular diseases are often considered to be a predominantly male health problem, and it has been suggested that testosterone exerts deleterious effects on cardiovascular function; however, few experimental studies support this suggestion.…

Pseudocoarction of the aorta and crossed fused ectopic kidney assessed by multidetector computed tomography

Aortic pseudocoarctation is a congenital abnormality consisting of an elongated aortic arch with a kink at level of the isthmus. However, unlike coarctation, significant flow obstruction is not associated with pseudocoarctation, although there is an…

Tags: 2010, Aorta, Bolen M A, Cardiovascular System & Cardiology, Crossed fused ectopic kidney, Journal Article or Conference Abstract Publication, Journal of cardiovascular computed tomography, Medical Imaging, Nuclear Medicine &, Pseudocoarctation, Radiology, Roselli E E, Tandon N S

Image Quality, Contrast Enhancement, and Radiation Dose of ECG-Triggered High-Pitch CT Versus Non-ECG-Triggered Standard-Pitch CT of the Thoracoabdominal Aorta

OBJECTIVE. We sought to compare image quality, contrast enhancement, and radiation dose in patients undergoing ECG-triggered high-pitch helical CT or non-ECG-synchronized helical CT of the thoracoabdominal aorta. MATERIALS AND METHODS. We…

Androgen-receptor defect abolishes sex differences in nitric oxide and reactivity to vasopressin in rat aorta

Contractions of rat thoracic aorta to vasopressin WP) are threefold higher in females (F) than in males (M), primarily because nitric oxide (NO) attenuation of contraction is greater in M. To determine the role of the androgen receptor (AR) in this…

MEDIAL CALCIFICATION (WHITLOCKITE) IN THE AORTA

Calcified deposits in the tunica media of the human aorta have been studied in 128 cases by light microscopy and by electron microscopy and analytical methods in selected samples. Although dissolved and not visible in routine histology with alum…

Tags: 1993, Andersen M E, Aorta, atheroma, Atherosclerosis, calcium, Cardiovascular System & Cardiology, drinking water, elastin, Journal Article, matrix vesicles, Reid J D, whitlockite

Testosterone causes direct relaxation of rat thoracic aorta.

Several recent studies have provided evidence that gonadal steroid hormones can exert acute (nongenomic) effects on both neural and vascular tissues. This study examines the acute effects of testosterone (T) on vascular reactivity of the rat thoracic…

Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice.

BACKGROUND: Heart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia. This study…

Complications and Perioperative Management of Patients Undergoing Thoracic Endovascular Aortic Repair.

Endovascular treatments have become increasingly common for patients with a variety of thoracic aortic pathologies. Although considered less invasive than traditional open surgical approaches, they are nonetheless complex procedures. Patients undergo…

Sex differences in nitric oxide-mediated attenuation of vascular reactivity to vasopressin are abolished by gonadectomy.

In the rat thoracic aorta, contractile responses to vasopressin are two-fold higher in females than in males, primarily because nitric oxide-mediated attenuation of contraction is greater in males than in females. To determine the role of the gonadal…

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