Browse Items (8 total)
- Tags: Neurodegenerative Diseases
Differential Effect Of Nimodipine In Attenuating Iron-induced Toxicity In Brain- And Blood-brain Barrier-associated Cell Types
Tags: 2012, Allen D D, Astrocytes, Biochemistry & Molecular Biology, Bohn K A, central-nervous-system, cerebrospinal-fluid, cultured astrocytes, DeSilva S F, Geldenhuys W J, intracerebral hemorrhage, Iron in brain, Journal Article or Conference Abstract Publication, Lockman J A, Metal toxicity, Neurochemical Research, Neurodegenerative Diseases, neurodegenerative disorders, Neurons, Neurosciences & Neurology, nimodipine, oxidative, parkinsons-disease, redox-active iron, Stress, substantia-nigra, transferrin receptor, Van der Schyf C J, Vascular endothelial cells
Inhibition Of Phosphorylation Of Trkb And Trkc And Their Signal Transduction By Alpha(2)-macroglobulin
Tags: 1998, alpha(2)-macroglobulin, Alzheimer's disease, Biochemistry & Molecular Biology, cerebrospinal-fluid, dopaminergic-neurons, Hu Y Q, Journal Article or Conference Abstract Publication, Journal of neurochemistry, Koo P H, Mitogen-Activated Protein Kinases, nerve growth-factor, neurite outgrowth, Neurodegenerative Diseases, Neurosciences & Neurology, neurotrophic factor, neurotrophins, phospholipase C-gamma 1, rat caudate-putamen, signal-transduction, tyrosine protein-kinase
Chronic exposure to a glyphosate-containing pesticide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditis elegans
Tags: 2018, 6-ohda, alzheimers-disease, Bailey D C, Brain, Burchfield S L, C. elegans, complex-i, degeneration, Denney R D, Department of Pharmaceutical Sciences, Environmental Sciences & Ecology, Environmental toxicology and pharmacology, Fitsanakis V A, Glyphosate, Herbicide, Hydrogen peroxide, Journal Article or Conference Abstract Publication, mechanisms, Mitochondrial inhibition, Negga R, NEOMED College of Pharmacy, Neurodegenerative Diseases, Oxidative Stress, parkinsons-disease, Pharmacology & Pharmacy, Pressley A S, Reactive oxygen, Snapp I B, SPECIES, Todt C E, Toxicology, Traynor W L
Why should we use multifunctional neuroprotective and neurorestorative drugs for Parkinson's disease?
Tags: 2007, A(2A) receptor antagonists, adenosine, alzheimers-disease, amyloid precursor protein, Antagonist, bcl-2 family-members, designed multiple ligands, double-blind, dual mechanism, Geldenhuys W J, iron chelation, Journal Article, ladostigil, M30, mao-b, monoamine-oxidase-b, Neurodegenerative Diseases, Neurosciences & Neurology, nmda receptor, Parkinsonism & Related Disorders, rasagiline, tea polyphenol (-)-epigallocatechin-3-gallate, Van der Schyf C J, Youdim M B H
Tags: 2006, alzheimers-disease, amyotrophic lateral sclerosis, Biochemistry & Molecular Biology, depressive illness, designed multiple ligands, Geldenhuys W J, hetero-cage compounds, iron chelator, Journal Article, Journal of neurochemistry, Lewy body disease, monoamine oxidase inhibitor, mptp-induced neurotoxicity, Neurodegenerative Diseases, Neurosciences & Neurology, nicotinic acetylcholine-receptors, nonsteroidal antiinflammatory drugs, parkinsons-disease, Schizophrenia, Van der Schyf C J, Youdim M B H
Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a Tauopathy Model of Alzheimer's Disease.
Tags: *Alzheimer Disease/complications/genetics/pathology, *Alzheimer's disease, *bone density, *microtubule-associated protein, *serotonin, *tau proteins, *tauopathies, 2017, Age Factors, Alzheimer's disease, Alzheimer's Disease – Complications, Alzheimer's Disease – Pathology, Animal, Animal Studies, Animals, Biological, Body Composition, Body Composition/genetics, Body Weight, Body Weight/genetics, Bone Density – Physiology, Bone Density/*physiology, Bone Diseases – Etiology, Bone Diseases/*etiology, Brain Stem – Pathology, Dengler-Crish Christine M, Department of Pharmaceutical Sciences, Disease Models, Dorsal Raphe Nucleus/*pathology, Female, Inbred C57BL, Journal of Alzheimer's disease : JAD, Male, Mice, Models, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurons – Metabolism, Neurons – Pathology, Neurons/metabolism/pathology, Oxidoreductases – Metabolism, Phosphorylation, Serotonin – Metabolism, Serotonin/*metabolism, Smith Matthew A, tau Proteins/*genetics/metabolism, Tauopathies/complications/genetics, Transgenic, Tryptophan Hydroxylase/metabolism, Wilson Gina N
Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy.
Tags: 2018, Alzheimer's disease, Animal, Animals, Antigens, Bemiller Shane M, Bhaskar Kiran, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cannon Judy L, Cardona Astrid E, Cells – Drug Effects, Cells – Metabolism, Cells – Pathology, Chemokine CX3CL1/*genetics/metabolism, Cognition Disorders – Etiology, Cognition Disorders/etiology, Crish Samuel D, CX3CL1, CX3CR1, Cytokines, Cytokines – Metabolism, Cytokines/metabolism, Department of Pharmaceutical Sciences, Differentiation/genetics/metabolism, Disease Models, Formica Shane V, Gene Expression Regulation/drug effects/*genetics, Genes, Genes – Drug Effects, Journal of neuroinflammation, Jung Steffen, Kim Ki-Wook, Kokiko-Cochran Olga N, Lamb Bruce T, Learning, Lipopolysaccharides, Lipopolysaccharides/toxicity, Maphis Nicole M, Maze Learning, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia, Microglia/drug effects/*metabolism/pathology, Miller Crystal M, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurodegenerative Diseases – Pathology, Neuroinflammation, Surface, Surface – Metabolism, Tau, tau Proteins/genetics/metabolism, Tauopathies, Tauopathies/complications/genetics/*pathology, Transgenic, Wilson Gina N, Xu Guixiang