Browse Items (51 total)
- Tags: Department of Pharmaceutical Sciences, 2018
Evidence of Wnt/beta-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.
Tags: *Alzheimer's disease, *Beta catenin, *Bone mineral density, *neurodegeneration, *Tauopathy, *Wnt proteins, *Wnt Signaling Pathway, 2018, Alzheimer Disease/*genetics/*metabolism, Animal, Animals, Ball Hope C, beta Catenin/metabolism, Bone and Bones/*metabolism, Bone Density, Bone Remodeling/genetics, Brain/*metabolism, Cooper Lisa Noelle, Dengler-Crish Christine M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Female, Gene Expression, Lin Li, Male, Mice, NEOMED College of Medicine, NEOMED College of Pharmacy, Neurobiology of aging, Novak Kimberly M, Osteogenesis/genetics, Osteoporosis/etiology/genetics, tau Proteins/*metabolism, Tauopathies/genetics/*metabolism, Wnt Proteins/metabolism
Anterograde Tract Tracing for Assaying Axonopathy and Transport Deficits in Glaucoma.
Tags: *Axonal transport, *Axonopathy, *Neuronal tracing, *Optic nerve, *superior colliculus, 2018, Animal, Animals, Axonal Transport, Axons/metabolism/*pathology/physiology, Cholera Toxin/*metabolism, Confocal, Crish Samuel D, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, Disease Models, Glaucoma/*diagnostic imaging/metabolism/physiopathology, Humans, Methods in molecular biology (Clifton, N.J.), Mice, Microscopy, NEOMED College of Medicine, NEOMED College of Pharmacy, Rats, Schofield Brett R, Visual Pathways
Ahr And Cyp1a2 Genotypes Both Affect Susceptibility To Motor Deficits Following Gestational And Lactational Exposure To Polychlorinated Biphenyls
Tags: 2018, Aryl hydrocarbon receptor, Cerebellum, Colter B T, Curran C P, CYP1A2, Department of Pharmaceutical Sciences, developmental exposure, dioxin-like compounds, dopamine concentrations, Fleming S M, Fowler J P, Garber H F, Harding G D, Hooven M K, Howes A A, in-utero, Infante S K, Lang A L, MacDougall M C, Motor function, NEOMED College of Pharmacy, Neurosciences & Neurology, Neurotoxicology, Nigrostriatal pathways, parkinsons-disease, pcb exposure, perinatal exposure, Pharmacology & Pharmacy, Polychlorinated biphenyls, prenatal exposure, Risk Assessment, school-age, Stegman M, Taylor K R, Toxicology
Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.
Tags: 2018, American journal of physiology. Endocrinology and metabolism, Berejnaia Olga, Chen Ying, Daurio Natalie A, Department of Pharmaceutical Sciences, dyslipidemia, Insulin Resistance, Kasumov Takhar, Kelley David E, Kinetics, lipid turnover, Liu Jinqi, Mass spectrometry, Mayoral Rafael, McLaren David G, NEOMED College of Pharmacy, Petrov Aleksandr, Previs Stephen F, Wang Sheng-Ping, Yin Wu, Zhang Guo-Fang
Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.
Tags: 2018, Animals, Budge Kevin M, Department of Anatomy & Neurobiology, Department of Pharmaceutical Sciences, GPNMB, Humans, Immune System/metabolism, Membrane Glycoproteins/chemistry/*metabolism, Molecular neurobiology, Neal Matthew L, NEOMED College of Medicine, NEOMED College of Pharmacy, Nerve Degeneration/pathology, Neurodegeneration, Neurodegenerative Diseases/*metabolism/therapy, Neuroinflammation, Neuroprotection, Richardson Jason R, Safadi Fayez F
Interprofessional education model for geriatric falls risk assessment and prevention.
Tags: 2018, BMJ open quality, Brown Diane K, College of Medicine, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drost Jenifer C, Fleming Eileen, Fosnight Sue, Hazelett Susan, Hovland Cynthia A, Kropp Denise J, McQuown Colleen, Morgan Abigail, NEOMED College of Medicine, NEOMED College of Pharmacy, Niederriter Joan E, Ortiz Figueroa Fabiana, Patton Rikki, Scott Edward Demond, Steiner Richard P, Whitford Maureen
RNAseq analysis of hippocampal microglia after kainic acid-induced seizures.
Tags: 2018, Animals, Bosco Dale B, Department of Pharmaceutical Sciences, Eyo Ukpong B, Feng Lijie, Gene Expression Profiling, Gene Ontology, Hippocampus/*pathology, Huang Jun, Immunity, Interferon-beta/metabolism, Kainic Acid, Mice, Microglia/*metabolism/*pathology, Molecular brain, NEOMED College of Pharmacy, Peng Jiyun, Richardson Jason R, RNA/*methods, Seizures/*chemically induced, Sequence Analysis, Signal Transduction/genetics, Tang Ke, Up-Regulation/genetics, Wang Hui, Wu Gongxiong, Wu Long-Jun, Xu Zhiyan, Yan Cheng, Zheng Jiaying
Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy.
Tags: 2018, Alzheimer's disease, Animal, Animals, Antigens, Bemiller Shane M, Bhaskar Kiran, Biological, Calcium Binding Proteins – Metabolism, Calcium-Binding Proteins/metabolism, Cannon Judy L, Cardona Astrid E, Cells – Drug Effects, Cells – Metabolism, Cells – Pathology, Chemokine CX3CL1/*genetics/metabolism, Cognition Disorders – Etiology, Cognition Disorders/etiology, Crish Samuel D, CX3CL1, CX3CR1, Cytokines, Cytokines – Metabolism, Cytokines/metabolism, Department of Pharmaceutical Sciences, Differentiation/genetics/metabolism, Disease Models, Formica Shane V, Gene Expression Regulation/drug effects/*genetics, Genes, Genes – Drug Effects, Journal of neuroinflammation, Jung Steffen, Kim Ki-Wook, Kokiko-Cochran Olga N, Lamb Bruce T, Learning, Lipopolysaccharides, Lipopolysaccharides/toxicity, Maphis Nicole M, Maze Learning, Mice, Microfilament Proteins – Metabolism, Microfilament Proteins/metabolism, Microglia, Microglia/drug effects/*metabolism/pathology, Miller Crystal M, Models, Mutation, Mutation/genetics, NEOMED College of Pharmacy, Nerve Tissue Proteins, Nerve Tissue Proteins – Metabolism, Neurodegenerative Diseases, Neurodegenerative Diseases – Complications, Neurodegenerative Diseases – Pathology, Neuroinflammation, Surface, Surface – Metabolism, Tau, tau Proteins/genetics/metabolism, Tauopathies, Tauopathies/complications/genetics/*pathology, Transgenic, Wilson Gina N, Xu Guixiang
Chronic exposure to a glyphosate-containing pesticide leads to mitochondrial dysfunction and increased reactive oxygen species production in Caenorhabditis elegans
Tags: 2018, 6-ohda, alzheimers-disease, Bailey D C, Brain, Burchfield S L, C. elegans, complex-i, degeneration, Denney R D, Department of Pharmaceutical Sciences, Environmental Sciences & Ecology, Environmental toxicology and pharmacology, Fitsanakis V A, Glyphosate, Herbicide, Hydrogen peroxide, Journal Article or Conference Abstract Publication, mechanisms, Mitochondrial inhibition, Negga R, NEOMED College of Pharmacy, Neurodegenerative Diseases, Oxidative Stress, parkinsons-disease, Pharmacology & Pharmacy, Pressley A S, Reactive oxygen, Snapp I B, SPECIES, Todt C E, Toxicology, Traynor W L