Browse Items (5 total)
- Tags: Recombinant Proteins/metabolism
HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7alpha-hydroxylase gene (CYP7A1).
Tags: *Receptors, *Transcription, 2000, Animals, Base Sequence, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Chiang J Y, Cholesterol 7-alpha-Hydroxylase/*genetics, COUP Transcription Factor II, COUP Transcription Factors, Cultured, Department of Integrative Medical Sciences, DNA Primers, DNA-Binding Proteins/*metabolism, Genes, Genetic, Hepatocyte Nuclear Factor 4, Humans, Journal of lipid research, Liver/metabolism, Luciferases/genetics, Mutation, NEOMED College of Medicine, Phosphoproteins/*metabolism, Promoter Regions, Rats, Recombinant Proteins/metabolism, Reporter, Sprague-Dawley, Steroid, Stroup D, Transcription Factors/*metabolism, Tumor Cells
Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling.
Tags: *MAP Kinase Signaling System, *Signal Transduction, 2016, Abdelmagid Samir M, Animals, Cell Differentiation, Cells, Cultured, Department of Anatomy & Neurobiology, Experimental & molecular medicine, Eye Proteins/*metabolism, Geldenhuys Werner J, Hyaluronan Receptors/*metabolism, Inbred C57BL, Jaber Fatima A, Male, Mbimba Thomas S, Membrane Glycoproteins/*metabolism, Mice, Moussa Fouad M, NEOMED College of Medicine, Novak Kimberly, Osteoclasts/*cytology/metabolism, RANK Ligand/metabolism, Recombinant Proteins/metabolism, Safadi Fayez F, Sondag Gregory R, Yu Bing
Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway.
Tags: *Intracellular Signaling Peptides and Proteins, 2001, Amyloid beta-Peptides/*biosynthesis/metabolism, Apoptosis Regulatory Proteins, Apoptosis/*physiology, Carrier Proteins/genetics/*physiology, Caspases/*metabolism, Chang X, Cultured, Du H, Enzyme Activation, Guo Q, Humans, Kinetics, Leucine Zippers, Neuroblastoma, Peptide Fragments/*biosynthesis/metabolism, Recombinant Proteins/metabolism, The Journal of biological chemistry, Time Factors, Transfection, Tumor Cells, Xie J
Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.
Tags: *Cytochrome b5, *Free radicals, *Reactive oxygen species, *redox cycling, 2018, Aleksunes Lauren M, Benzoquinones/*metabolism, Cytochrome-B(5) Reductase/*metabolism, Free Radicals/metabolism, Fussell Karma C, Heck Diane E, Humans, Jan Yi-Hua, Kinetics, Laskin Debra L, Laskin Jeffrey D, Liver, Microsomes, Mishin Vladimir, NADP/metabolism, Nitrofurantoin/*metabolism, Oxidation-Reduction, Oxygen Consumption, Reactive Oxygen Species/metabolism, Recombinant Proteins/metabolism, Richardson Jason R, Szilagyi John T, Toxicology and applied pharmacology, Wang Yun, Yang Shaojun
Selective Targeting of Heme Protein in Cytochrome P450 and Nitric Oxide Synthase by Diphenyleneiodonium.
Tags: *cytochrome P450, *flavoenzymes, *heme, *nitric oxide synthase, *Reactive oxygen species, 2016, Aleksunes Lauren M, Animals, Cytochrome P-450 Enzyme Inhibitors/*pharmacology, Cytochrome P-450 Enzyme System/*metabolism, Department of Pharmaceutical Sciences, Dose-Response Relationship, Drug, Heck Diane E, Heindel Ned D, Heme/*antagonists & inhibitors/metabolism, Humans, Jan Yi-Hua, Laskin Debra L, Laskin Jeffrey D, Liver/drug effects/enzymology, Mice, Microsomes, Mishin Vladimir, NEOMED College of Pharmacy, Nitric Oxide Synthase Type II/*antagonists & inhibitors/metabolism, Nitric Oxide/metabolism, Onium Compounds/*pharmacology, Rats, Recombinant Proteins/metabolism, Richardson Jason R, Sprague-Dawley, Szilagyi John T, Time Factors, Toxicological sciences : an official journal of the Society of Toxicology