We examined the effect of L-dihydroxyphenylalanine (L-DOPA) infusion in vitro upon dopamine (DA) and dihydroxyphenylacetic acid (DOPAC) output from superfused corpus striatum of vehicle and reserpine or tetrabenazine (TBZ) treated male rats.…
Combination-sensitive neurons serve as the fundamental processing unit in Sussman and colleagues' proposal for the neural representation of of stop consonants. This commentary describes recent studies in the mustached bat that show how ubiquitous and…
This study was designed to develop and validate a new computerized version of the Symptom Driven Diagnostic System for Primary Care (SDDS-PC) and example its feasi bility in primary care practice. One thousand and one patients (ages 18-70) coming for…
Interbody cage devices, used to assist interbody fusion, are rapidly gaining popularity in the surgical management of chronic low back pain. This update provides a structural classification of commonly used devices and assesses them against a set of…
White coat ceremonies are a recent phenomenon in medical education. Selected as a symbol by the Arnold P. Gold Foundation to impress upon medical students the importance of compassion and humility, the white coat has had a long association with all…
Chemical sensitivity has been recognized for an extended period. Over the last 30 years or more, there has been a growing number of chemicals to which humans are being exposed. Some people have become sensitive to one or more of these chemicals and…
Sperry's proposal that subjective experience plays a major role in brain function and in the emergence of mind, consciousness and human values represent a challenge to behaviorism as the dominant force in psychology. Mind is viewed as an emergent…
We studied the nonspecific nature of the histologic findings in the gastric antral vascular ectasia (GAVE) syndrome by using a morphometric comparison with common gastric lesions including hyperplastic polyps and gastritis. Five clinicopathologically…
Serum albumin is a poor nutritional marker, but it is a good prognostic marker correlating with morbidity and mortality. However, IV albumin administration in hypoalbuminemic patients does not decrease tube feeding-associated diarrhea or intolerance,…
This meta-analysis used all original articles from 1966 to June 1996 that fit the preset inclusion criteria to examine the clinical effectiveness of intermittent pneumatic compression (IPC) devices in preventing deep vein thrombosis (DVT) and…
Hausler & Schmid (1995) challenged the long held opinion that AL 288-1 (Australopithecus afarensis), popularly known as "Lucy," was female. They concluded that AL 288-1 was most probably male ("Lucifer") and, by extension, the hypodigm for A.…
BACKGROUND. The content and context of family practice outpatient visits have never been fully described, leaving many aspects of family practice in a "black box," unseen by policymakers and understood only in isolation. This article describes…
BACKGROUND. The content and context of family practice outpatient visits have never been fully described, leaving many aspects of family practice in a "black box," unseen by policymakers and understood only in isolation. This article describes…
This study was undertaken to establish the presence and characteristics of receptors for [D-Trp(6)]LH-RH on the membranes of human ovarian cancer. Specific binding of [I-125, D-Trp(6)]LH-RH was found in 29 of 37 (78.4%) ovarian cancers and in 6 of 11…
Sepsis stimulates an increase in the number and activity of mononuclear phagocytes in systemic host-defence organs. The present study was conducted to define the ultrastructural and cytochemical characteristics of the mononuclear phagocytes that…
Aging differentially alters forms of long-term potentiation in rat hippocampal area CAl. J. Neurophysiol. 79: 334-341, 1998. Long-term potentiation (LTP) of the Schaffer collateral/commissural inputs to CAI in the hippocampus was shown to consist of…
It has been demonstrated that castration alters the functioning of the olfactory bulb (OB)-norepinephrine (NE) system. In the present experiment, we examined one of the mechanisms by which castration modulates the OB-NE system by comparing NE uptake…
Osteopetrosis describes a heterogeneous group of congenital bone disorders characterized by a generalized increase in skeletal mass resulting from a primary reduction in osteoclast mediated bone resorption, The pathogenetic heterogeneity is due to…
In light of the overwhelming response to the previous publication in Neuroscience and Biobehavioral Reviews (1993, 17, 21-41) regarding trends in place conditioning (either preference or aversion), the present work constitutes a five-year follow-up…
A two-lever, food-motivated, operant technique was employed to train the purportedly serotonergically dysfunctional Fawn-Hooded (FH) rat to discriminate 1.5 mg/kg MDMA. Once all 10 male subjects learned the MDMA-vehicle discrimination at criterion…
The benzodiazepine flunitrazepam (Rohypnol) was employed to control differentially discriminative performance in 10 Sprague-Dawley rats on a food-motivated FR10 schedule. The training dose was 2.5 mg/kg, and 20 min was employed between…
The co-administration of D-lysergic acid diethylamide (LSD; 'Acid') and 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy'; 'XTC'), has reached a prevalence that has allowed for the street terminology 'candyflipping' to describe the combination.…
For the first time, we report Klebsiella pneumoniae as an enteroinvasive food-borne pathogen transmitted from a hamburger. A 28-year-old previously healthy African-American male ingested a portion of a hamburger from a fast food chain. Symptoms of…
When a patient's total serum calcium level drops below 8.9 mg/dL, first determine whether the hypocalcemia is real. Measure the serum level of ionized calcium or (because 40% of calcium is bound to protein) adjust the total serum calcium level for…
Thorough investigation of complex cases of acid-base disturbances indudes verification of pH, determination of respiratory and metabolic components, calculation of the anion gap, assessment of the degree of compensation; and analysis of the…
This article demonstrated a systematic approach to acid-base problem solving through the application of the so-called "Rules of Five." This technique was compared with other options for acid-base problem solving, namely, clinicians' use of gestalt or…
OBJECTIVE: To characterize hypertrophic osteoarthropathy (HOA) in skeletons to allow its recognition in the archeologic record. METHODS: Individuals diagnosed in life with diseases known to cause HOA were examined from the Hamman-Todd, Grant, and…
OBJECTIVES: To assess the specificity of dactylitis for the diagnosis of spondyloarthropathy, sarcoidosis, and gout; and to characterize dactylitis specifically associated with gout. METHODS: Dactylitis was prospectively assessed among all…
