Browse Items · NEOMED Bibliography Database

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

Can ultrasound be used to predict malignancy in patients with a thyroid nodule and an indeterminate fine-needle aspiration biopsy?

PURPOSE: The purpose of this study was to evaluate whether ultrasonography is helpful in predicting malignancy in patients with a thyroid nodule and atypia/follicular lesion of undetermined significance (AFLUS). METHODS: All patients with a…

Chemotherapy completion in elderly women with ovarian, primary peritoneal or fallopian tube cancer - An NRG oncology/Gynecologic Oncology Group study.

PURPOSE: A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline Instrumental Activities of Daily Living (IADL) score with ability to complete 4 cycles of first line…

Quality of life, symptoms and care needs in patients with persistent or recurrent platinum-resistant ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.

OBJECTIVES: The goals of treating recurrent platinum-resistant ovarian cancer are palliative, aimed at reducing symptoms and improving progression free survival. A prospective trial was conducted to determine the prevalence and severity of symptoms,…

Uterine problems discovered after presumed hysterectomy: the Manchester operation revisited.

BACKGROUND: The Manchester operation consists of amputation of the cervix, leading some patients to believe that they have undergone a hysterectomy. CASES: A 69-year-old woman with vaginal discharge proved to have a well-differentiated adenocarcinoma…

Tags: *Hysterectomy, 1997, 80 and over, Aged, Amputation/*methods, Cervix Uteri/*surgery, DeLancey J O, Devine J B, Diagnosis, Differential, Female, Hopkins M P, Humans, Obstetrics and gynecology, Uterine Diseases/*diagnosis/surgery, Uterine Prolapse/*surgery

Difficulty in predicting bacteremia in elderly emergency patients.

STUDY OBJECTIVES: To characterize the clinical presentation and identify factors predictive of bacteremia in elderly patients. DESIGN: Retrospective review of emergency department charts, hospital records, and microbiology reports. SETTING: Community…

Case finding for cognitive impairment in elderly emergency department patients.

STUDY OBJECTIVES: To determine the feasibility of a case-finding program for cognitive impairment in elderly emergency department patients, and to describe the prevalence of cognitive impairment in screened patients and identify factors associated…

Evaluation of the patient with seizures: an evidence based approach.

Statistics tell us that as many as 1 in 20 members of the population will suffer a seizure at some point in their lifetime, a figure which becomes even more likely if one lives to the age of 80. Thus, a careful evidence based approach to the patient…

Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

The efficacy of a new pharmacokinetically enhanced formulation of amoxycillin/clavulanate (AMX/CA) 2000/125 mg, twice daily, designed to provide adequate levels of amoxycillin over the 12-h dosing interval to eradicate penicillin-resistant…

Tags: *Treatment Outcome, 2002, 80 and over, Adolescent, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination/administration & dosage/*pharmacokinetics/pharmacology/*therapeutic use, Amoxicillin/adverse effects/therapeutic use, Bacterial, Bacterial/drug therapy/immunology, Bronchitis/drug therapy/microbiology, Combination/adverse effects/*therapeutic use, Department of Internal Medicine, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Drug Therapy, Female, File Thomas M Jr, Follow-Up Studies, Humans, International journal of antimicrobial agents, Jacobs Michael R, Male, Microbial Sensitivity Tests, Middle Aged, Multicenter Studies as Topic, NEOMED College of Medicine, Pneumonia, Poole Michael D, Respiratory Tract Infections/*drug therapy/metabolism/microbiology, Streptococcal Infections/*drug therapy/metabolism/microbiology, Streptococcus pneumoniae/*drug effects, Wynne Brian

Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia.

This 10-year retrospective study assessed the epidemiology and outcomes of patients with Fusobacterium bacteraemia (FB) at a tertiary-care hospital in the

Tags: *Hospital Mortality, 2013, 80 and over, Adult, Aged, Bacteremia – Mortality, Bacteremia – Physiopathology, Bacteremia/*mortality/physiopathology, Bonilla H F, Creatinine – Blood, Creatinine/blood, Epidemiology and infection, Female, Fusobacterium Infections – Mortality, Fusobacterium Infections – Physiopathology, Fusobacterium Infections/*mortality/physiopathology, Goldberg E A, Hewit M, Hospital Mortality, Hospitals, Human, Humans, Intensive Care Units – Statistics and Numerical Data, Intensive Care Units/statistics & numerical data, Length of Stay – Statistics and Numerical Data, Length of Stay/statistics & numerical data, Male, Middle Age, Middle Aged, Retrospective Design, Retrospective Studies, Risk Factors, Special – Statistics and Numerical Data, Tertiary Care Centers/*statistics & numerical data, Treatment Outcome, Treatment Outcomes, United States, United States/epidemiology, Venkat-Ramani T

Geriatric Disaster Preparedness.

INTRODUCTION: The elderly population has proven to be vulnerable in times of a disaster. Many have chronic medical problems for which they depend on medications or medical equipment. Some older adults are dependent on caregivers for managing their…

The assessment and treatment of back and neck pain: an initial investigation in a primary care practice-based research network.

AIM: The purpose of this study was to conduct an exploratory examination of the current state of non-malignant acute and chronic back and neck pain assessment and management among primary care providers in a multi-site, practice-based research…

The epidemiology of respiratory tract infections.

Respiratory tract infections (RTIs) are the most common, and potentially most severe, of infections treated by health care practitioners. Lower RTIs along with influenza, are the most common cause of death by infection in the United States. Risk…

Mindfulness as a predictor of positive reappraisal and burnout in standardized patients.

BACKGROUND: Standardized patients (SPs) portray emotionally intense roles that can have unintended deleterious effects including burnout. PURPOSE: This study explored SP characteristics that could serve as protective factors against these adverse…

Clinical characteristics of Chlamydia pneumoniae infection as the sole cause of community-acquired pneumonia.

The clinical characteristics of 26 patients with community-acquired pneumonia due to Chlamydia pneumoniae as the only identified pathogen who required hospitalization were evaluated. Most patients (18) had reinfection based on serological results.…

Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia.

BACKGROUND: Ceftaroline, the active form of ceftaroline fosamil, is a broad-spectrum cephalosporin with bactericidal activity against pathogens causing community-acquired pneumonia (CAP), including Streptococcus pneumoniae. Ceftaroline was evaluated…

Results of the promoting effective advance care planning for elders (PEACE) randomized pilot study.

The specific aim of the PEACE pilot study was to determine the feasibility of a fully powered study to test the effectiveness of an in-home geriatrics/palliative care interdisciplinary care management intervention for improving measures of…

Tags: *Quality of Life, 2014, 80 and over, Activities of Daily Living, advance care planning, Advance Care Planning/*organization & administration, Aged, Albanese Teresa H, Allen Kyle R, Case Management – Methods, Chi Square Test, College of Medicine, Community-Institutional Relations, Comparative Studies, Decision Making, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Disease Management, Ertle Denise, Family, Female, Fosnight Susan M, Frail Elderly, Geriatric Assessment/methods, Hazelett Susan E, Health Promotion, Health Resource Utilization, Health Services for the Aged/organization & administration, Home Care Services/*organization & administration, Human, Humans, Interdisciplinary Communication, Kropp Denise J, Long Term Care, Long-Term Care/*organization & administration, Male, Medicaid – Ohio, Moore Pamela S, Multidisciplinary Care Team, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohio, Outcomes (Health Care), Palliative Care, Palliative Care/organization & administration, Patient, Physicians, Pilot Projects, Pilot Studies – Ohio, Population health management, Program Evaluation, Psychological Tests, Quality of Life, Radwany Steven M, Random Assignment, Reference Values, Repeated Measures, Scales, Spiritual Care, T-Tests, Treatment Outcome

SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.

BACKGROUND: Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. METHODS: A total of 863 adults with…

Tags: *clinical trial, *Community-acquired, *Pneumonia, *solithromycin, *Streptococcus pneumoniae, 2016, 80 and over, Administration, Adult, Aged, Anti-Bacterial Agents/*administration & dosage/adverse effects, Bacterial, Bacterial/diagnosis/*drug therapy/*microbiology, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/diagnosis/*drug therapy/*microbiology, Comorbidity, Das Anita F, Department of Internal Medicine, Drug Resistance, Female, Fernandes Prabhavathi, File Thomas M Jr, Fluoroquinolones/*administration & dosage/adverse effects, Gonong Joven Roque V, Humans, Intravenous, Jamieson Brian D, Keedy Kara, Macrolides/*administration & dosage/adverse effects, Male, Microbial Sensitivity Tests, Middle Aged, Moxifloxacin, NEOMED College of Medicine, Oldach David, Oral, Pneumonia, Rewerska Barbara, Sheets Amanda, Taylor David, Treatment Outcome, Triazoles/*administration & dosage/adverse effects, Vucinic-Mihailovic Violeta

Can aggressive treatment of diabetic foot infections reduce the need for above-ankle amputation?

We retrospectively evaluated the charts of 112 patients with diabetic foot infection to determine if early aggressive surgical intervention improves outcome. All patients were classified into two groups on the basis of the timing of surgical…

Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.

OBJECTIVES: Short-course therapy has been advocated for the treatment of community-acquired pneumonia (CAP). We compared the efficacy and safety of 5 and 7 day courses of gemifloxacin for outpatient treatment of mild-moderate CAP. PATIENTS AND…

FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

OBJECTIVES: Ceftaroline, the active form of the prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated with community-acquired pneumonia (CAP), including Streptococcus pneumoniae and…

Tags: 2011, 80 and over, Aged, Bacteria, Bacteria/isolation & purification, Bacterial – Drug Therapy, Bacterial/*drug therapy, Ceftriaxone – Administration and Dosage, Ceftriaxone – Adverse Effects, Ceftriaxone/administration & dosage/adverse effects, Cephalosporins – Administration and Dosage, Cephalosporins – Adverse Effects, Cephalosporins/*administration & dosage/*adverse effects, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections/*drug therapy, Critchley Ian A, Department of Internal Medicine, Double-Blind Method, Double-Blind Studies, Eckburg Paul B, Female, File Thomas M Jr, Friedland H David, Human, Humans, Infusions, Intravenous, Lee Jon, Llorens Lily, Low Donald E, Male, Middle Age, Middle Aged, NEOMED College of Medicine, Pneumonia, RANDOMIZED controlled trials, Talbot George H, The Journal of antimicrobial chemotherapy, Thye Dirk A, Treatment Outcome, Treatment Outcomes

Physiological Indices of Stress Prior to and Following Total Knee Arthroplasty Predict the Occurrence of Severe Post-Operative Pain.

OBJECTIVE: The severe pain and disability associated with osteoarthritis often motivate individuals to undergo arthroplastic surgery. However, a significant number of surgical patients continue to experience pain following surgery. Prior research has…

Tags: *Cardiovascular, *Cortisol, *Epinephrine, *Post-operative Pain, *Severity of Illness Index, *Stress, *Surgery, 2016, 80 and over, Aged, Arthroplasty, Catecholamines – Urine, Center for Epidemiological Studies Depression Scale, Cohort Studies, Cremeans-Smith Julie K, Data Analysis Software, Delahanty Douglas L, Descriptive Statistics, Effect Size, Female, Greene Kenneth, Human, Humans, Hydrocortisone – Urine, Knee, Knee/*adverse effects/psychology, Male, Middle Age, Middle Aged, Nonexperimental Studies, Ohio, Pain, Pain Measurement/methods, Pain medicine (Malden, Mass.), Physiological, Postoperative Pain – Risk Factors, Postoperative/*diagnosis/etiology/*psychology, Predictive Value of Tests, Prospective Studies, Psychological/complications/*diagnosis/*psychology, Regression, Replacement, Scales, Stress, Summated Rating Scaling, Treatment Outcome

Two-portal endoscopic carpal tunnel release: an outcome analysis of 333 hands.

Outcome data were collected on 239 patients who underwent endoscopic release of the transverse carpal ligament. The procedure was performed on 333 hands in 239 patients. All patients had failed to respond to nonoperative management for carpal tunnel…

Tags: 1998, 80 and over, Adult, Aged, Annals of plastic surgery, Carpal Tunnel Syndrome/physiopathology/*surgery, Davies B W, Endoscopy/*methods, Female, Fritz A M, Humans, Male, Middle Aged, Pennington G A, Treatment Outcome

Parotid gland metastasis from renal cell carcinoma.

OBJECTIVE: To discuss the diagnosis and management of metastatic renal cell carcinoma presenting as a parotid mass by studying such cases. STUDY DESIGN: Retrospective review. METHODS: Identification of 24 previously reported cases of renal cell…

Tags: 2002, 80 and over, Aged, Biopsy, Carcinoma, Diagnosis, Differential, Female, Hlivko Thomas J, Humans, Kidney Neoplasms/*pathology, Needle, Park Youn W, Parotid Neoplasms/pathology/*secondary, Renal Cell/pathology/*secondary, Retrospective Studies, The Laryngoscope

Ventricular tachycardia in acute myocardial infarction: the role of hypophosphatemia.

The relationship between serum concentration of certain electrolytes and the pathogenesis of ventricular arrhythmia in myocardial infarction has been the subject of frequent review. The role of hypophosphatemia in the pathogenesis of arrhythmia in…

Spinous process osteotomies to facilitate lumbar decompressive surgery.

STUDY DESIGN: A technique for lumbar decompression using spinous process osteotomies is described, and the outcomes are studied prospectively. OBJECTIVE: To describe a technique that affords a wide exposure for decompression while minimizing damage…

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

US emergency department visits for hip fracture, 1992-2000.

BACKGROUND: Hip fracture is a significant injury for older persons. Little has been reported about emergency department (ED) care of these patients. OBJECTIVE: To characterize the management of older patients treated in the ED for hip fracture with…

Tags: 2004, 80 and over, Age Factors, Aged, Analgesia/statistics & numerical data, Camargo Carlos A Jr, Emergency Medical Services/*statistics & numerical data, Emond Jennifer A, European journal of emergency medicine : official journal of the European Society for Emergency Medicine, Female, Gerson Lowell W, Hip Fractures/diagnosis/*epidemiology/therapy, Humans, Male, Middle Aged, Sex Factors, United States/epidemiology

A comparison of the National Ambulatory Medical Care Survey (NAMCS) measurement approach with direct observation of outpatient visits.

BACKGROUND: The National Ambulatory Medical Care Survey (NAMCS) informs a wide range of important policy and clinical decisions by providing nationally representative data about outpatient practice. However, the validity of the NAMCS methods has not…

Ischemic colitis revisited: a prospective study identifying hypercoagulability as a risk factor.

BACKGROUND: Although causes for ischemic colitis have been identified, many cases are deemed idiopathic. Some reports suggest an association between ischemic colitis and coagulation disorders. Our purpose was to explore the relationship of ischemic…

Anatomical Look Into OnabotulinumtoxinA Injection for Chronic Migraine Headache.

BACKGROUND AND OBJECTIVES: While existing studies about onabotulinumtoxinA for chronic migraines have focused on injection location and appropriate dosing, little consideration has been given to patient body habitus and its potential impact on…

Tags: 2018, 80 and over, Adolescence, Adolescent, Adult, Aged, Anatomic Landmarks/anatomy & histology/*diagnostic imaging, Ansari Hossein, Blaha Taryn, Body Regions, Body Regions – Anatomy and Histology, Botulinum Toxins, Botulinum Toxins – Administration and Dosage, Chronic Disease, Female, Human, Humans, Male, Middle Age, Middle Aged, Migraine, Migraine – Drug Therapy, Migraine Disorders/*diagnostic imaging/*drug therapy, Narouze Samer, Neck Muscles, Neck Muscles – Anatomy and Histology, Neck Muscles – Drug Effects, Neck Muscles/anatomy & histology/*diagnostic imaging/drug effects, Pilot Projects, Pilot Studies, Random Allocation, Random Assignment, Regional anesthesia and pain medicine, Swanson Marco, Tomography, Totonchi Ali, Type A/*administration & dosage, Wu-Fienberg Yuewei, X-Ray Computed – Methods, X-Ray Computed/methods, Young Adult, Zardouz Shawn

Long-term results of percutaneous lumbar decompression for LSS: two-year outcomes.

OBJECTIVE: The aim of this report was to evaluate the long-term effectiveness and safety of mild lumbar decompression for the treatment of neurogenic claudication associated with lumbar spinal stenosis. This technique uses a percutaneous dorsal…

Factors Predicting Recurrence of Clostridium difficile Infection (CDI) in Hospitalized Patients: Retrospective Study of More Than 2000 Patients.

BACKGROUND: Clostridium difficile infection (CDI) has increased in incidence and severity worldwide, causing direct costs estimated to range from US $3.2 billion to $4.8 billion. The aim of this study was to investigate and identify factors that…

Cardiopulmonary resuscitation in the hospitalized patient: impact of system-based variables on outcomes in cardiac arrest.

BACKGROUND: A better understanding of the factors affecting the outcome of inpatient cardiopulmonary resuscitation (CPR) is crucial in making key clinical decisions. We aim to study the impact of various patient-related and hospital-related variables…

Proton pump inhibitors impact on post-endoscopic retrograde cholangiopancreatography pancreatitis.

Computed Tomography Artifact Created by Air in the X-ray Tube Oil.

A subtle artifact of patchy hypodensities in computed tomography images of the head mimicked acute or subacute cerebral infarct. The cause of the artifact was air in the oil of the x-ray tube. The artifact manifested only when the acquisition…

Sonoelastography of Breast Lymphoma.

Breast lymphomas only account for approximately 0.15% of malignant breast carcinomas. Half of these are primary lymphomas, and the other half are metastatic to the breast. Ultrasound elastography has been proven to aid in the diagnosis of breast…

Outcomes of Patients With Syncope and Suspected Dementia.

OBJECTIVES: Syncope and near-syncope are common in patients with dementia and a leading cause of emergency department (ED) evaluation and subsequent hospitalization. The objective of this study was to describe the clinical trajectory and short-term…

Tags: 2018, 80 and over, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, Adler David H, Aged, Bastani Aveh, Baugh Christopher W, Caterino Jeffrey M, Clark Carol L, Dementia – Diagnosis – In Old Age, Dementia – Risk Factors, Dementia – Therapy, Department of Emergency Medicine, Diercks Deborah B, Emergency, Gibson Tommy A, Holden Timothy R, Hollander Judd E, Human, Iatrogenic Disease, Inpatients, interviews, Length of Stay, Malveau Susan E, Middle Age, NEOMED College of Medicine, Nicks Bret A, Nishijima Daniel K, Office Visits, Outcome Assessment, Outcomes (Health Care), Patient Assessment, Patient Discharge, Physicians, Prospective Studies, Shah Manish N, Stiffler Kirk A, Storrow Alan B, Sun Benjamin C, Surveys, Syncope – Diagnosis, Syncope – In Old Age, Syncope – Mortality, Weiss Robert E, Wilber Scott T, Yagapen Annick N

Thrombopoietic status of patients on haemodialysis.

Thrombocytopenia is a potential dialysis-related treatment complication. Developments in bio-compatible dialyser membranes have decreased the occurrence of thrombocytopenia. We investigated whether thrombopoiesis is impaired in haemodialysis patients…

The CARE approach to reducing diagnostic errors.

BACKGROUND: Diagnostic errors appear to be the most common, costly, and dangerous of all medical mistakes. There has been a notable increase on the focus of error prevention as part of a growing patient safety movement. However, diagnostic errors…

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