Browse Items (97 total)

Dr. S: Diffuse pain, possible drug-seeking behavior. Ms. K: Doc, I hurt everywhere. I’ve had all kinds of tests and no one can figure out what’s wrong with me. I went to the ER again last week because my chest was hurting and I was afraid it was my…

The translator and I arrived at a modest home in a neighborhood just outside of downtown. We were halfway through the interview process – at perhaps number 20 or 21 of the 45 we had planned to conduct. The neighborhood and home were much like the…

My family and friends (and even my doctor!) think I’m a strong person, but I don’t see it that way. I just do what I need to do to get through each day. Taking care of my family, friends, and sometimes even complete strangers is actually what keeps…

My next patient to be seen during office hours is the typical one whose name is instantly recognizable and causes a shiver much like what a sour candy ball does to your mouth. The interaction is pleasurable enough, but the end result is always…

A twisting of the ovary and/or fallopian tube on its vascular and ligamentous supports, blocking adequate blood flow to the ovary. Rapid diagnosis and intervention are necessary to preserve ovarian function. Most often seen in women of reproductive…

Milagros is a 50-year-old Puerto Rican woman whose family I met while over the course of 3 months volunteering at a family medicine clinic in South Bronx. She was accompanied by her two teenage daughters, Amparo, 18, and Beatriz, 13, and her grandson…

“It’s about time you got in here.” I was just a few minutes late getting started for Kathleen’s appointment, so it seemed apparent she was in a hurry. Kathleen sat in a chair next to our examination table. She was restless and her excess body weight…

Urban corner stores in Northeast Ohio have a reputation for contributing to neighborhood demise. Sales of liquor, cigarettes, lottery tickets, and other high-calorie low-nutrition foods along with high check-cashing fees have given corner stores…

This is a story of three patients seen by a newly licensed physician shortly after completing residency training. The physician was born, raised, and educated in the northeastern United States before moving to Texas where he was unprepared to handle…

More than a decade has elapsed since the original statement of life design as an innovative and internationally-constructed paradigm for careers science and practice. Responding to the challenges of work and career in contemporary times, life design…

Career Construction Counselling (CCC) is a narrative intervention that supports individuals in the elaboration of narrative identity and career construction. CCC theory, research, and practice has benefited from the Innovative Moments Model (IMM) to…

The purpose of this review is to briefly summarize the roles of alcohol (ethanol) and related compounds in promoting cancer and inflammatory injury in many tissues. Long-term chronic heavy alcohol exposure is known to increase the chances of…

The need to remain current with updated skills continues as a challenge for adults and older adult workers. Learning new information and skills to keep abreast with changes in everyday activities and in the workplace is a lifelong challenge. In this…

Wild primates encounter complex matrices of substrates that differ in size, orientation, height, and compliance, and often move on multiple, discontinuous substrates within a single bout of locomotion. Our current understanding of primate gait is…

The number of refugees and asylum seekers throughout the world continues to increase, leading to increasing challenges in meeting healthcare needs of these individuals. Women's antenatal health is of particular concern due to their vulnerability to…

Purpose: Medical student specialty choices have significant downstream effects on the availability of physicians and, ultimately, the effectiveness of health systems. This study investigated how medical student specialty preferences change over time…

The article aims to increase awareness of and dialogue about the achievable benefits and existing challenges of health care organizations' engagement in community development as to continue national efforts which aimed at achieving social, economic,…

Pruritus is a common presenting diagnosis associated with a myriad of localized and systemic conditions. Due to many underlying causes, it can be challenging for the provider to assess. Symptoms often persist, causing frustration for the patient and…

Objectives: Primate diagonal sequence (DS) gaits are often argued to be an adaptation for moving and foraging in the fine‐branch niche; however, existing data have come predominantly from laboratory studies that are limited in taxonomic breadth and…

Context: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its…

Macrophages play a crucial role in the pathogenesis of atherosclerosis, but the molecular mechanisms remain poorly understood. Here we show that microRNA-34a (miR-34a) is a key regulator of macrophage cholesterol efflux and reverse cholesterol…

Aberrant liver sirtuin 1 (SIRT1), a mammalian NAD+-dependent protein deacetylase, is implicated in the pathogenesis of alcoholic liver disease. However, the role of intestinal SIRT1 in alcoholic liver disease is presently unknown. This study…

Psychotic disorders are not uncommon in late life. These disorders often have varied etiologies, different clinical presentations, and are associated with significant morbidity and mortality among the older adult population. Psychotic disorders in…

STUDY OBJECTIVE: Older adults with syncope are commonly treated in the emergency department (ED). We seek to derive a novel risk-stratification tool to predict 30-day serious cardiac outcomes. METHODS: We performed a prospective, observational study…

BACKGROUND: The formation of a bolus of food is critical for proper feeding function, and there is substantial variation in the size and shape of a bolus prior to a swallow. Preterm infants exhibit decreased abilities to acquire and process food, but…

A therapeutic strategy that can combat the multifaceted nature of neuroinflammation pathology was investigated. Thus, we fabricated PEG-PdLLA polymersomes and evaluated the efficacy in co-delivery of simvastatin (Sim, as a repurposed…

OBJECTIVE: As one of the most popular social media used around the world, YouTube may be able to serve as a new medium for mental health education. This study aims to analyze and compare the performance of YouTube in disseminating dementia education…

Inflammation is a complex physiological process that poses a serious threat to people's health. However, the potential molecular mechanisms of inflammation are still not clear. Moreover, there is lack of effective anti-inflammatory drugs that meet…

BACKGROUND: Target-homing drug delivery systems are now gaining significant traction for use as novel therapeutic approaches in antitumor targeting for cancer therapy. Numerous targeted drug delivery systems have been designed to improve the…

Food texture preference and product acceptance are hypothesized to be influenced by mouth behavior. Recent work identified four mouth behavior (MB) groups that describe most consumers in the United States: Chewers, Crunchers, Smooshers, and Suckers.…
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