Browse Items · NEOMED Bibliography Database

Gemifloxacin versus amoxicillin/clavulanate in the treatment of acute exacerbations of chronic bronchitis. The 070 Clinical Study group.

Six hundred patients were evaluated in this randomized, double-blind, double-dummy, multicenter, parallel-group study comparing the efficacy and safety of gemifloxacin (320 mg once-daily for 5 days) and amoxicillin/clavulanate (500/125 mg three-times…

Tags: *Fluoroquinolones, 2000, 80 and over, Acute-Phase Reaction, Adult, Aged, Amoxicillin/pharmacology/therapeutic use, Anti-Infective Agents/adverse effects/pharmacology/*therapeutic use, Bronchitis/*drug therapy, Chronic Disease, Clavulanic Acid/pharmacology/therapeutic use, Combination/pharmacology/*therapeutic use, Department of Internal Medicine, Double-Blind Method, Drug Therapy, Female, File T, Garau J, Gemifloxacin, Haemophilus influenzae/drug effects, Humans, Journal of chemotherapy (Florence, Italy), Lode H, Lynch S, Male, Microbial Sensitivity Tests, Middle Aged, Moraxella (Branhamella) catarrhalis/drug effects, Multicenter Studies as Topic, Naphthyridines/adverse effects/pharmacology/*therapeutic use, NEOMED College of Medicine, Schlemmer B, Streptococcus pneumoniae/drug effects, Treatment Outcome, Young C

Upper-Limb Recovery After Stroke: A Randomized Controlled Trial Comparing

BACKGROUND AND PURPOSE: This study compared the effect of cyclic neuromuscular electrical stimulation (NMES), electromyographically (EMG)-triggered NMES, and sensory stimulation on motor impairment and activity limitations in patients with upper-limb…

Vascular complications associated with transcatheter aortic valve replacement.

Transcatheter aortic valve replacement (TAVR) is now an accepted pathway for aortic valve replacement for patients who are at prohibitive, severe and intermediate risk for traditional aortic valve surgery. However, with this rising uptrend and…

Morton's interdigital neuroma: a comprehensive treatment protocol.

One hundred fifteen patients with signs and symptoms of Mortons' interdigital neuroma were studied in an attempt to evaluate the efficacy of a staged treatment program. The first stage consisted of patient education, footwear modifications, and…

Tags: 1995, Adolescent, Adult, Aged, Bennett G L, Female, Foot & ankle international, Graham C E, Humans, Male, Mauldin D M, Middle Aged, Nerve Compression Syndromes/diagnosis/*surgery, Neuroma/diagnosis/*surgery, Palliative Care, Peripheral Nerves/surgery, Soft Tissue Neoplasms/diagnosis/*surgery, Toes/*innervation, Treatment Outcome

Complications and Perioperative Management of Patients Undergoing Thoracic Endovascular Aortic Repair.

Endovascular treatments have become increasingly common for patients with a variety of thoracic aortic pathologies. Although considered less invasive than traditional open surgical approaches, they are nonetheless complex procedures. Patients undergo…

Relevance of routine admission electrocardiograms for psychiatric patients.

OBJECTIVE: To make clinically relevant recommendations for electrocardiogram (ECG) testing among psychiatric patients, the study examined the practice of ordering ECGs for this population. METHODS: The records of 4,045 patients consecutively admitted…

Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles.

The widespread clinical success with most gallium compounds in cancer therapy is markedly hampered by lack of tumor specific accumulation, poor tumor permeability and undesirable toxicity to healthy tissues. The aim of this work was to investigate…

The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept-The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial.

BACKGROUND AND PURPOSE: The capillary index score (CIS) is based on the hypothesis that areas lacking capillary blush on pretreatment cerebral digital subtraction angiograms correspond to nonviable cerebral tissue. METHODS: Pretreatment digital…

Tags: *cerebral cortex, *infarction, *stroke, *tissue, 2016, Al-Ali Firas, Angiography, Bender Evin N, Berkhemer Olvert A, Brain, Brain Ischemia/*diagnostic imaging/therapy, Brain/*diagnostic imaging, Capillaries, Capillaries/*diagnostic imaging, Cerebral Ischemia, Cerebral Ischemia – Therapy, Checklists, Comparative Studies, Computed Tomography Angiography/*methods, Digital Subtraction – Methods, Digital Subtraction/*methods, Dillon William P, Dippel Diederik W J, Elias John J, Endovascular Procedures/methods, Evaluation Research, Human, Humans, Lingsma Hester F, Majoie Charles B L M, Multicenter Studies, RANDOMIZED controlled trials, Roos Yvo B W E M, Scales, stroke, Stroke – Therapy, Stroke/*diagnostic imaging/therapy, Treatment Outcome, Treatment Outcomes, Validation Studies, van der Lugt Aad, van Oostenbrugge Robert J, van Zwam Wim H, Yousman Wina P

An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.

RATIONALE: Preclinical studies indicate that adult stem cells induce tissue repair by activating endogenous stem cells through the stromal cell-derived factor-1:chemokine receptor type 4 axis. JVS-100 is a DNA plasmid encoding human stromal…

Thirty-Day Readmissions After Transcatheter Aortic Valve Replacement in the United States: Insights From the Nationwide Readmissions Database.

BACKGROUND: Readmissions after cardiac procedures are common and contribute to increased healthcare utilization and costs. Data on 30-day readmissions after transcatheter aortic valve replacement (TAVR) are limited. METHODS AND RESULTS: Patients…

Tags: *aortic stenosis, *costs and cost analysis, *length of stay, *Patient Readmission/economics, *readmission, *rehospitalization, *transcatheter aortic valve implantation, *transcatheter aortic valve replacement, 2017, 80 and over, Abbott J Dawn, Aged, Aortic Valve Stenosis/diagnosis/economics/*surgery, Aronow Wilbert S, Bhatt Deepak L, Chatterjee Saurav, Circulation. Cardiovascular interventions, Comorbidity, Databases, Department of Internal Medicine, Factual, Female, Fonarow Gregg C, Gheewala Neil, Goldsweig Andrew, Gordon Paul C, Greenbaum Adam B, Gupta Tanush, Hospital Costs, Humans, Khera Sahil, Kolte Dhaval, Length of Stay, Male, NEOMED College of Medicine, Patient Discharge, Postoperative Complications/etiology, Risk Factors, Sardar M Rizwan, Sharaf Barry, Skilled Nursing Facilities, Time Factors, Transcatheter Aortic Valve Replacement/*adverse effects/economics, Treatment Outcome, United States

Predictors of mortality for nursing home-acquired pneumonia: a systematic review.

BACKGROUND: Current risk stratification tools, primarily used for CAP, are suboptimal in predicting nursing home acquired pneumonia (NHAP) outcome and mortality. We conducted a systematic review to evaluate current evidence on the usefulness of…

A note regarding problems with interaction and varying block sizes in a comparison of endotracheal tubes.

A randomized clinical experiment to compare two types of endotracheal tubes utilized a block design where each of the six participating anesthesiologists performed tube insertions for an equal number of patients for each type of tube. Five…

Tags: *Randomized Controlled Trials as Topic, *Research Design, 2014, Algorithms, Anesthesiology/*methods, Computational and mathematical methods in medicine, Data Interpretation, Einsporn Richard L, Humans, Intratracheal/*instrumentation, Intubation, Jia Zhenyu, Models, Sample Size, Statistical, Treatment Outcome

Scientific and ethical issues in the use of placebo controls in clinical trials.

Tags: *Ethics, *Patient Advocacy, *Placebos, 1994, Annual review of public health, Clark P I, Clinical Trials as Topic/*standards, Humans, Leaverton P E, Medical, Placebo Effect, Safety, Science/*standards, Treatment Outcome

Catastrophic chest pain: blinded by cardiopulmonary disease.

A 53-year-old man with a history of diabetic foot ulcer, osteomyelitis, coronary artery disease, hypertension and hyperlipidaemia, presented with chest pain of 3 weeks duration. Eleven days earlier, the patient had had a drug-eluting stent (DES)…

Assessment of time to clinical response, a proxy for discharge readiness, among hospitalized patients with community-acquired pneumonia who received either ceftaroline fosamil or ceftriaxone in two phase III FOCUS trials.

The primary driver of health care costs for patients with community-acquired pneumonia (CAP) is the hospital length of stay (LOS). Unfortunately, hospital LOS comparisons are difficult to make from phase III CAP trials because of their structured…

Oxybutynin 3% gel for the treatment of primary focal hyperhidrosis in adolescents and young adults.

BACKGROUND/OBJECTIVES: There are no reliably effective, well-tolerated topical agents for the treatment of hyperhidrosis. We sought to evaluate the efficacy and tolerability of oxybutynin 3% gel in adolescents and young adults with primary focal…

Short-term functional decline and service use in older emergency department patients with blunt injuries.

BACKGROUND: Injuries are a common reason for emergency department (ED) visits by older patients. Although injuries in older patients can be serious, 75% of these patients are discharged home after their ED visit. These patients may be at risk for…

Tags: *Activities of Daily Living, 2010, 80 and over, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, Academic Medical Centers, Activities of Daily Living, Aged, Allen Kyle R, Blanda Michelle, Bone/physiopathology/therapy, Clinical Assessment Tools, Comorbidity, Confidence Intervals, Department of Emergency Medicine, Descriptive Statistics, Emergency Care – In Old Age, Emergency Patients – In Old Age, Emergency Service, Family, Female, Fisher's Exact Test, Fractures, Functional Status – In Old Age, Geriatric Assessment, Geriatric Functional Assessment, Gerson Lowell W, Health Resource Utilization – In Old Age, Hospital/*statistics & numerical data, Hospitals, Human, Humans, Logistic Models, Logistic Regression, Longitudinal Studies, Male, Mental Status Schedule, NEOMED College of Medicine, Nonpenetrating – In Old Age, Nonpenetrating/*physiopathology/*therapy, OARS Multidimensional Functional Assessment Questionnaire, Odds Ratio, Ohio, Outcome Assessment, Outpatients, P-Value, Predictive Value of Tests, Prospective Studies, Questionnaires, Record Review, ROC Curve, Scales, Summated Rating Scaling, Surveys and Questionnaires, T-Tests, Teaching, Treatment Outcome, Treatment Outcomes, Wilber Scott T, Wounds

Intranasal lidocaine for the treatment of migraine headache: a randomized, controlled trial.

OBJECTIVE: To evaluate the effect of intranasal lidocaine for immediate relief (5 minutes) of migraine headache pain. METHODS: A randomized, double-blind, placebo-controlled clinical trial at two university-affiliated community teaching hospitals…

Contrast-enhanced ultrasound detection and treatment guidance in a renal transplant patient with renal cell carcinoma.

Contrast-enhanced ultrasonography (CEUS) is an imaging modality that shows promise in the detection and characterization of renal masses, as well as treatment through CEUS-guided percutaneous radiofrequency ablation. These techniques may be…

Gastric Lipoma: A Review of the Literature.

Gastric lipoma is a rare benign tumor of the stomach. The imaging characteristics are diagnostic because the lesion has fat attenuation on computed tomography and demonstrates characteristics of fat on magnetic resonance images. On ultrasound, the…

Proton pump inhibitors impact on post-endoscopic retrograde cholangiopancreatography pancreatitis.

Evaluation of factors associated with achieving glycemic control in a pharmacist-managed diabetes clinic.

The aim of this study was to identify factors that are associated with patients achieving goal A1c after 6 months in a pharmacist-managed diabetes clinic. This study is a descriptive, retrospective chart review of patients with type 2 diabetes…

Tags: 2014, Ambulatory Care, Ambulatory Care/organization & administration, American journal of therapeutics, Blood Glucose – Drug Effects, Blood Glucose/drug effects, Boros Melanie L, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Frazee Lawrence A, Glycated Hemoglobin A/metabolism, Glycosylated – Metabolism, Hemoglobin A, Human, Humans, Hypoglycemic Agents – Administration and Dosage, Hypoglycemic Agents – Therapeutic Use, Hypoglycemic Agents/administration & dosage/*therapeutic use, Insulin – Administration and Dosage, Insulin – Therapeutic Use, Insulin/administration & dosage/therapeutic use, Kostoff Matthew D, Male, Middle Age, Middle Aged, Moorman John M, NEOMED College of Medicine, NEOMED College of Pharmacy, Pharmaceutical Services/*organization & administration, Pharmacists – Administration, Pharmacists/*organization & administration, Pharmacy Service – Administration, Prospective Studies, Retrospective Design, Retrospective Studies, Social Work – Statistics and Numerical Data, Social Work/statistics & numerical data, Treatment Outcome, Treatment Outcomes, Type 2 – Drug Therapy, Type 2/*drug therapy

Cardiopulmonary resuscitation in the hospitalized patient: impact of system-based variables on outcomes in cardiac arrest.

BACKGROUND: A better understanding of the factors affecting the outcome of inpatient cardiopulmonary resuscitation (CPR) is crucial in making key clinical decisions. We aim to study the impact of various patient-related and hospital-related variables…

A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice.

OBJECTIVES: Breast cancer-related lymphedema (BCRL) represents a major complication of breast cancer treatment, impacting the quality of life for breast cancer survivors that develop it. The purpose of this review is to evaluate the literature…

Long-term results of percutaneous lumbar decompression for LSS: two-year outcomes.

OBJECTIVE: The aim of this report was to evaluate the long-term effectiveness and safety of mild lumbar decompression for the treatment of neurogenic claudication associated with lumbar spinal stenosis. This technique uses a percutaneous dorsal…

Gynecomastia: an outcome analysis.

BACKGROUND: Gynecomastia refers to the presence of femalelike mammary glands in a male. This disorder can lead to significant psychologic stress and self-consciousness. This study consists of a chart review of 174 patients treated surgically between…

Tags: 2004, Adolescent, Adult, Aged, Annals of plastic surgery, Child, Gynecomastia/*surgery, Humans, Lehman James A Jr, Male, Middle Aged, Parker Michael G, Pedersen John C, Retrospective Studies, Tantri M Devi Prasad, Treatment Outcome, Wagner Douglas S, Wiesman Irvin M

Increased intraabdominal pressure in abdominoplasty: delineation of risk factors.

BACKGROUND: Abdominoplasty is associated with a 1.1 percent risk of deep venous thrombosis. This has been attributed to rectus plication causing intraabdominal hypertension, known to effect decreased venous return, venous stasis, and thus thrombosis.…

The influence of obesity and volume of resection on success in reduction mammaplasty: an outcomes study.

BACKGROUND: Indications for breast reduction surgery include neck pain, back pain, shoulder pain, and an intertriginous rash. Previous studies have established that bilateral breast reduction surgery is highly effective in relieving these symptoms.…

Tags: *Mammaplasty/methods, 2005, Adult, Alfonso David R, Back Pain/epidemiology, Body Mass Index, Comorbidity, Exanthema/epidemiology, Female, Humans, Insurance Coverage, Middle Aged, Neck Pain/epidemiology, Obesity/*epidemiology, Plastic and reconstructive surgery, Retrospective Studies, Shoulder Pain/epidemiology, Treatment Outcome, Wagner Douglas S

Effectiveness of a group exercise program in a long-term care facility: a randomized pilot trial.

OBJECTIVE: The purpose of this pilot was to determine whether a strength and flexibility program in frail long-term care facility (LTC) residents would result in improved function. DESIGN: A prospective, randomized, controlled, semicrossover trial…

Discoid lateral meniscus.

Tags: 1999, Child, Eilert R E, Fleissner P R, Humans, Magnetic Resonance Imaging, Menisci, Radiography, The American journal of knee surgery, Tibial/*abnormalities/anatomy & histology/diagnostic imaging/surgery, Treatment Outcome

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

Spinous process osteotomies to facilitate lumbar decompressive surgery.

STUDY DESIGN: A technique for lumbar decompression using spinous process osteotomies is described, and the outcomes are studied prospectively. OBJECTIVE: To describe a technique that affords a wide exposure for decompression while minimizing damage…

Microdecompression and uninstrumented single-level fusion for spinal canal stenosis with degenerative spondylolisthesis.

STUDY DESIGN: A retrospective review was completed on 21 patients who had a "least invasive" (one or two level) microdecompression and uninstrumented single-segment lumbar fusion for spinal canal stenosis with degenerative spondylolisthesis.…

Tags: 1998, Decompression, Dermatologic Surgical Procedures, Dissection, Follow-Up Studies, Hospital Costs, Humans, Length of Stay/economics, Lumbar Vertebrae/pathology, Magnetic Resonance Imaging, McCulloch J A, Retrospective Studies, Spinal Cord Compression/diagnosis/pathology/*surgery, Spinal Fusion/economics/*methods, Spinal Stenosis/diagnosis/pathology/*surgery, Spine, Spondylolisthesis/diagnosis/pathology/*surgery, Surgical/economics/*methods, Treatment Outcome

Focus issue on lumbar disc herniation: macro- and microdiscectomy.

This paper is based on a review, analysis, and discussion of the extensive literature on indications, technique, and complications of discectomy (macro and micro) for lumbar disc herniation. Outcomes for lumbar discectomy for disc herniation depend…

Tags: 1996, Adolescent, Adult, Diskectomy/*methods, Humans, Intervertebral Disc Displacement/*surgery, Lumbar Vertebrae/*pathology, McCulloch J A, Microsurgery/*methods, Middle Aged, Sciatica/etiology/therapy, Spine, Treatment Outcome

Uninstrumented posterolateral lumbar fusion for single level isolated disc resorption and/or degenerative disc disease.

The limited soft-tissue envelope technique for an uninstrumented single-level posterolateral lumbar fusion has been studied in a group of 23 patients. It resulted in a solid fusion in 21 of 23 (91%) patients. Overall, 18 of 23 (78%) patients had a…

Tags: 1999, Adult, Aged, Bone Resorption/diagnosis/*surgery, Female, Humans, Intervertebral Disc/diagnostic imaging/pathology/*surgery, Journal of spinal disorders, Lumbar Vertebrae/diagnostic imaging/pathology/*surgery, Magnetic Resonance Imaging, Male, McCulloch J A, Medical Illustration, Middle Aged, Radiography, Retrospective Studies, Spinal Diseases/diagnosis/*surgery, Spinal Fusion/*methods, Treatment Outcome

Defects of pars interarticularis in athletes: a protocol for nonoperative treatment.

The purpose of this study was to report the results of a specific treatment protocol for athletes with spondylolysis or spondylolisthesis of the lumbar spine. A retrospective study with recent follow-up was performed on 82 patients treated with…

Two-portal endoscopic carpal tunnel release: an outcome analysis of 333 hands.

Outcome data were collected on 239 patients who underwent endoscopic release of the transverse carpal ligament. The procedure was performed on 333 hands in 239 patients. All patients had failed to respond to nonoperative management for carpal tunnel…

Tags: 1998, 80 and over, Adult, Aged, Annals of plastic surgery, Carpal Tunnel Syndrome/physiopathology/*surgery, Davies B W, Endoscopy/*methods, Female, Fritz A M, Humans, Male, Middle Aged, Pennington G A, Treatment Outcome

Reduction mammaplasty: an outcome analysis.

Reduction mammaplasty is usually performed to relieve painful symptoms and physical signs of macromastia. Justification for reduction mammaplasty should be based on the probability of relieving these clinical signs and symptoms. This retrospective…

Tags: *Mammaplasty/adverse effects, 1995, Adolescent, Adult, Aged, Annals of plastic surgery, Dabbah A, Fat Necrosis/etiology, Female, Humans, Lehman J A Jr, Middle Aged, Parker M G, Retrospective Studies, Tantri D, Treatment Outcome, Wagner D S

Physiological Indices of Stress Prior to and Following Total Knee Arthroplasty Predict the Occurrence of Severe Post-Operative Pain.

OBJECTIVE: The severe pain and disability associated with osteoarthritis often motivate individuals to undergo arthroplastic surgery. However, a significant number of surgical patients continue to experience pain following surgery. Prior research has…

Tags: *Cardiovascular, *Cortisol, *Epinephrine, *Post-operative Pain, *Severity of Illness Index, *Stress, *Surgery, 2016, 80 and over, Aged, Arthroplasty, Catecholamines – Urine, Center for Epidemiological Studies Depression Scale, Cohort Studies, Cremeans-Smith Julie K, Data Analysis Software, Delahanty Douglas L, Descriptive Statistics, Effect Size, Female, Greene Kenneth, Human, Humans, Hydrocortisone – Urine, Knee, Knee/*adverse effects/psychology, Male, Middle Age, Middle Aged, Nonexperimental Studies, Ohio, Pain, Pain Measurement/methods, Pain medicine (Malden, Mass.), Physiological, Postoperative Pain – Risk Factors, Postoperative/*diagnosis/etiology/*psychology, Predictive Value of Tests, Prospective Studies, Psychological/complications/*diagnosis/*psychology, Regression, Replacement, Scales, Stress, Summated Rating Scaling, Treatment Outcome

FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

OBJECTIVES: Ceftaroline, the active form of the prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated with community-acquired pneumonia (CAP), including Streptococcus pneumoniae and…

Tags: 2011, 80 and over, Aged, Bacteria, Bacteria/isolation & purification, Bacterial – Drug Therapy, Bacterial/*drug therapy, Ceftriaxone – Administration and Dosage, Ceftriaxone – Adverse Effects, Ceftriaxone/administration & dosage/adverse effects, Cephalosporins – Administration and Dosage, Cephalosporins – Adverse Effects, Cephalosporins/*administration & dosage/*adverse effects, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections/*drug therapy, Critchley Ian A, Department of Internal Medicine, Double-Blind Method, Double-Blind Studies, Eckburg Paul B, Female, File Thomas M Jr, Friedland H David, Human, Humans, Infusions, Intravenous, Lee Jon, Llorens Lily, Low Donald E, Male, Middle Age, Middle Aged, NEOMED College of Medicine, Pneumonia, RANDOMIZED controlled trials, Talbot George H, The Journal of antimicrobial chemotherapy, Thye Dirk A, Treatment Outcome, Treatment Outcomes

Browse Items (123 total)