Browse Items · NEOMED Bibliography Database

Vitamin D supplementation to prevent falls in the elderly: evidence and practical considerations.

Pharmacists in both ambulatory and institutional settings are often in a position to help optimize the drug regimens of patients who are experiencing falls. Supplementation with vitamin D is an important emerging therapy for the prevention of falls.…

Parkinson's disease biomarker: a patent evaluation of WO2013153386.

INTRODUCTION: Parkinson's disease (PD) is a neurodegenerative movement disorder resultant from the loss of dopaminergic neurons in the brain. There is an urgent need for effective biomarkers that can be used in the early diagnosis of PD.…

Students as catalysts to increase community pharmacy-led direct patient care services.

OBJECTIVE: To describe the impact on community pharmacy service development of a faculty-student-pharmacist collaborative program offered by five U.S. colleges. SETTING: Colleges of pharmacy and community pharmacies in Arizona, Illinois, Ohio, Utah,…

Tags: *Community-Institutional Relations, *Students, 2015, Community Pharmacy Services/*organization & administration, Community-Institutional Relations, Comparative Studies, Cooperative Behavior, Curriculum, Delivery of Health Care/*organization & administration, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Education, Educational, Elswick Betsy M, Evaluation Research, Health Care Delivery – Administration, Health Services Research, Human, Humans, Jennings Brandon T, Journal of the American Pharmacists Association : JAPhA, McKinley Rebekah Jackowski, Models, Multicenter Studies, NEOMED College of Pharmacy, Patient Centered Care – Administration, Patient-Centered Care/*organization & administration, Pharmacy, Pharmacy/methods, Professional Role, Program Evaluation, Retail – Administration, Rodis Jennifer L, Students, Ulbrich Timothy R, United States, Validation Studies

Coaching for Success: A Residency Search Primer and Update for Preceptors and Faculty.

Pharmacy residency programs have become increasingly competitive in recent years, and changes to the residency search and application process have altered the process for matching with a residency. In this article, major residency topics, from the…

Improving Chronic Disease Outcomes Through Medication Therapy Management in Federally Qualified Health Centers.

INTRODUCTION: Appropriate management of chronic diseases, including proper use of medications, can lead to better disease control, decrease disease-related complications, and improve overall health. Pharmacists have been shown to positively affect…

Tags: *Quality Improvement, 2017, Adolescent, Adult, Aged, Antihypertensive Agents/*therapeutic use, Awad Magdi H, Blood Pressure, Chronic Disease – Drug Therapy, Chronic Disease – Therapy, Community Health Centers, Data Analysis Software, Department of Pharmacy Practice, Descriptive Research, Descriptive Statistics, Diabetes Education, Diabetes Mellitus – Therapy, Diabetes Mellitus/*drug therapy/metabolism, Female, Financing, Funding Source, Glasgow Kyle, Glycated Hemoglobin A/metabolism, Glycosylated, Government, Health Services, Hemoglobin A, Hornbeck Fox Carrie, Hospital/*methods, Human, Humans, Hypertension – Therapy, Hypertension/*drug therapy, Hypoglycemic Agents/*therapeutic use, Journal of primary care & community health, Male, Medically Underserved, Medication Management, medications, Middle Aged, Multicenter Studies, NEOMED College of Pharmacy, Ohio, Outcome Assessment (Health Care), Outcomes (Health Care), Patient Education as Topic, Pharmacists, Pharmacy, Pharmacy Service, Pilot Projects, Pilot Studies, Porter Brianne, primary care, Program Evaluation, Prospective Studies, Pryor Barbara, Referral and Consultation, Rodis Jennifer L, Self Care, Sevin Alexa, Young Adult

Patient Awareness and Expectations of Pharmacist Services During Hospital Stay.

BACKGROUND: There are insufficient data in the United States regarding patient awareness and expectations of hospital pharmacist availability and services. OBJECTIVE: The objective of this research is to assess patient awareness and expectations of…

Tags: *Anticipation, *Awareness, *Health Knowledge, 2017, 80 and over, Adolescent, Adult, Aged, Attitudes, Betka Eric M, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Health Services Accessibility, Hospital, Hospital/methods/*statistics & numerical data, Human, Humans, Inpatients, Inpatients/*psychology, Journal of pharmacy practice, King Philip K, Male, Marketing, Marketing/methods, Martin Steven J, Middle Aged, NEOMED College of Pharmacy, Patient Attitudes, patient awareness, Patient Education, patient expectations, Pharmacists/*statistics & numerical data, Pharmacy Service, pharmacy services, Practice, Pretest-Posttest Design, Professional Role, Professional-Patient Relations, Psychological, Social Marketing, Summated Rating Scaling, Surveys, Surveys and Questionnaires, United States, Young Adult

Impact of Tranexamic Acid in Total Knee and Total Hip Replacement.

OBJECTIVE: To evaluate the net clinical benefit of tranexamic acid use in patients undergoing total knee or total hip replacement. METHODS: This is a retrospective study of patients undergoing total knee or total hip replacement. The primary outcome…

Tags: 2017, Aged, Antifibrinolytic Agents/adverse effects/therapeutic use, Arthroplasty, Blood Transfusion, Blood Transfusion/statistics & numerical data, Boyle Jaclyn A, Case-Control Studies, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Female, Hemoglobins – Analysis, Hemoglobins/metabolism, Hip, Hip/*methods, Human, Humans, Journal of pharmacy practice, Knee, Knee/*methods, Length of Stay – Evaluation, Length of Stay/statistics & numerical data, Male, NEOMED College of Pharmacy, Outcome Assessment, Replacement, Retrospective Design, Retrospective Studies, Soric Mate M, total hip replacement, total knee replacement, tranexamic acid, Tranexamic Acid – Administration and Dosage, Tranexamic Acid/adverse effects/*therapeutic use, Venous Thromboembolism – Risk Factors, Venous Thromboembolism/epidemiology

Repackaging of Intravenous Fat Emulsions: A Clinical Conundrum.

To accommodate small fluid volumes, repackaging of intravenous fat emulsions (IVFEs) is frequently performed in institutions providing parenteral nutrition to neonates and smaller pediatric patients. However, some consider this an unsafe practice.…

Interprofessional education model for geriatric falls risk assessment and prevention.

Background: One in three people over the age of 65 fall every year, with 1/3 sustaining at least moderate injury. Falls risk reduction requires an interprofessional health team approach. The literature is lacking in effective models to teach students…

Prevention, detection and intervention with delirium in an acute care hospital: a feasibility study.

Background. The prevalence of delirium in acute care hospitals ranges from 5-86%. Delirious patients are at greater risk of negative health outcomes and their care is often more costly. Aim. To determine the feasibility of a full-scale trial to test…

Tags: 2009, Allen Kyle, Anthony Mary, Benedict Lynn, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Fleming Eileen, Fosnight Sue, Hazelett Susan, Holder Carolyn, International journal of older people nursing, Ludwick Ruth, NEOMED College of Medicine, NEOMED College of Pharmacy, Zafirau William, Zeller Rich

Proton pump inhibitors impact on post-endoscopic retrograde cholangiopancreatography pancreatitis.

Evaluation of factors associated with achieving glycemic control in a pharmacist-managed diabetes clinic.

The aim of this study was to identify factors that are associated with patients achieving goal A1c after 6 months in a pharmacist-managed diabetes clinic. This study is a descriptive, retrospective chart review of patients with type 2 diabetes…

Tags: 2014, Ambulatory Care, Ambulatory Care/organization & administration, American journal of therapeutics, Blood Glucose – Drug Effects, Blood Glucose/drug effects, Boros Melanie L, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Frazee Lawrence A, Glycated Hemoglobin A/metabolism, Glycosylated – Metabolism, Hemoglobin A, Human, Humans, Hypoglycemic Agents – Administration and Dosage, Hypoglycemic Agents – Therapeutic Use, Hypoglycemic Agents/administration & dosage/*therapeutic use, Insulin – Administration and Dosage, Insulin – Therapeutic Use, Insulin/administration & dosage/therapeutic use, Kostoff Matthew D, Male, Middle Age, Middle Aged, Moorman John M, NEOMED College of Medicine, NEOMED College of Pharmacy, Pharmaceutical Services/*organization & administration, Pharmacists – Administration, Pharmacists/*organization & administration, Pharmacy Service – Administration, Prospective Studies, Retrospective Design, Retrospective Studies, Social Work – Statistics and Numerical Data, Social Work/statistics & numerical data, Treatment Outcome, Treatment Outcomes, Type 2 – Drug Therapy, Type 2/*drug therapy

Mineralocorticoid Receptor Antagonist Utilization in a Nationally Representative Heart Failure With Reduced Ejection Fraction Outpatient Population: A Cross-Sectional Study.

BACKGROUND: Mineralocorticoid receptor antagonists (MRAs) improve survival among patients with heart failure with reduced ejection fraction (HFrEF); however, studies have identified low utilization rates. No study has evaluated the prevalence and…

Tags: 2018, American journal of therapeutics, Boyle Jaclyn Ann, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Fredrickson Mary Elizabeth, Joyner Kayla Rena, Kleven Casondra Lee, Moorman John Michael, NEOMED College of Pharmacy, Soric Mate Michael, Turosky Jodie Zlotnik

Exploring the scope of post-intensive care syndrome therapy and care: engagement of non-critical care providers and survivors in a second stakeholders meeting.

BACKGROUND: Increasing numbers of survivors of critical illness are at risk for physical, cognitive, and/or mental health impairments that may persist for months or years after hospital discharge. The post-intensive care syndrome framework…

Tags: *Health Status, *Intensive Care Units, 2014, Awareness, Bemis-Dougherty Anita, Bienvenu O Joseph, Black Gary, Brady Susan, Brodsky Martin B, Continuity of Patient Care/*organization & administration, Critical care medicine, Critical Illness/*psychology, Davidson Judy E, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Deutschman Cliff, Doepp Diana, Elliott Doug, Flatley Carl, Fosnight Sue, Gittler Michelle, Gomez Belkys Teresa, Harvey Maurene A, Health Education, Hopkins Ramona O, Humans, Hyzy Robert, Iwashyna Theodore J, Louis Deborah, Mandel Ruth, Maxwell Carol, Mental Health, Muldoon Sean R, Needham Dale M, NEOMED College of Pharmacy, Perme Christiane S, Reilly Cynthia, Robinson Marla R, Rubin Eileen, Schmidt David M, Schuller Jessica, Scruth Elizabeth, Siegal Eric, Spill Gayle R, Sprenger Sharon, Straumanis John P, Survivors/*psychology, Sutton Pat, Swoboda Sandy M, Syndrome, Twaddle Martha L, United States, Wagner Jason, Weinert Craig, Wunsch Hannah

Results of the promoting effective advance care planning for elders (PEACE) randomized pilot study.

The specific aim of the PEACE pilot study was to determine the feasibility of a fully powered study to test the effectiveness of an in-home geriatrics/palliative care interdisciplinary care management intervention for improving measures of…

Tags: *Quality of Life, 2014, 80 and over, Activities of Daily Living, advance care planning, Advance Care Planning/*organization & administration, Aged, Albanese Teresa H, Allen Kyle R, Case Management – Methods, Chi Square Test, College of Medicine, Community-Institutional Relations, Comparative Studies, Decision Making, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Disease Management, Ertle Denise, Family, Female, Fosnight Susan M, Frail Elderly, Geriatric Assessment/methods, Hazelett Susan E, Health Promotion, Health Resource Utilization, Health Services for the Aged/organization & administration, Home Care Services/*organization & administration, Human, Humans, Interdisciplinary Communication, Kropp Denise J, Long Term Care, Long-Term Care/*organization & administration, Male, Medicaid – Ohio, Moore Pamela S, Multidisciplinary Care Team, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohio, Outcomes (Health Care), Palliative Care, Palliative Care/organization & administration, Patient, Physicians, Pilot Projects, Pilot Studies – Ohio, Population health management, Program Evaluation, Psychological Tests, Quality of Life, Radwany Steven M, Random Assignment, Reference Values, Repeated Measures, Scales, Spiritual Care, T-Tests, Treatment Outcome

Anti-edema action of thyroid hormone in MCAO model of ischemic brain stroke: Possible association with AQP4 modulation.

The use of neuroprotective strategies to mitigate the fatal consequences of ischemic brain stroke is a focus of robust research activity. We have previously demonstrated that thyroid hormone (T3; 3,3',5-triiodo-l-thyronine) possesses neuroprotective…

Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.

Although statins and other pharmacological approaches have improved the management of lipid abnormalities, there exists a need for newer treatment modalities especially for the management of hypertriglyceridemia. Lipoprotein lipase (LPL), by…

Tags: 2017, Animals, Cardiovascular Diseases/drug therapy/*enzymology, Darvesh Altaf S, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery Today, Geldenhuys Werner J, Humans, Lin Li, Lipoprotein Lipase/chemistry/*metabolism, Metabolic Diseases/drug therapy/*enzymology, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Sadana Prabodh

Overcoming missed opportunities in diabetes management to improve outcomes for hospitalized patients with diabetes.

AIMS: The purpose of this study is to assess the impact of hospitalization on

Assessment of a structured longitudinal professional identity development curriculum for pharmacy students.

BACKGROUND AND PURPOSE: To describe and assess a longitudinal Professional Identity Development (PID) curriculum at Northeast Ohio Medical Universities (NEOMED) College of Pharmacy. EDUCATIONAL ACTIVITY AND SETTING: Northeast Ohio Medical University,…

Tags: 2018, Boyle Jaclyn, Coffey Cory P, Currents in pharmacy teaching & learning, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Hoffman Alexander, NEOMED College of Medicine, NEOMED College of Pharmacy, Pokorny Anita, Professional development, Professional identity, Schneider Stacey, Student pharmacist development

Toolkit for US colleges/schools of pharmacy to prepare learners for careers in academia.

INTRODUCTION: The objective of this article is to provide an academic toolkit for use by colleges/schools of pharmacy to prepare student pharmacists/residents for academic careers. METHODS: Through the American Association of Colleges of Pharmac…

Preparing students for residency interviews through a residency interview boot camp.

BACKGROUND AND PURPOSE: To describe the offering of the residency boot camp activity at one college of pharmacy for students in their fourth professional year. EDUCATIONAL ACTIVITY AND SETTING: Student pharmacists in their final professional year of…

Identifying motivators and barriers to student completion of instructor evaluations: A multi-faceted, collaborative approach from four colleges of pharmacy.

OBJECTIVE: To identify motivators and barriers to pharmacy student completion of instructor evaluations, and to develop potential strategies to improve the evaluation process. METHODS: Completed at four Ohio Colleges of Pharmacy, Phase I consisted of…

Novel compounds that target lipoprotein lipase and mediate growth arrest in acute lymphoblastic leukemia.

Over the past decade, the therapeutic strategies employed to treat B-precursor acute lymphoblastic leukemia (ALL) have been progressively successful in treating the disease. Unfortunately, the treatment associated dyslipidemia, either acute or…

Tags: *Acute lymphoblastic leukemia, *Cancer, *Co-culture model, *Lipids, *Lipoprotein lipase, *Metabolism, 2018, Amides/chemistry/metabolism/pharmacology, Antineoplastic Agents/*chemistry/metabolism/pharmacology, Binding Sites, Bioorganic & medicinal chemistry letters, Cell Line, Cell Proliferation/drug effects, Coculture Techniques, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Dyslipidemias/complications/metabolism/pathology, Geldenhuys Werner J, Gibson Laura F, Humans, Lipoprotein Lipase/antagonists & inhibitors/*metabolism, Mesenchymal Stem Cells/cytology/metabolism, Molecular Docking Simulation, Nair Rajesh R, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Piktel Debbie, Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications/metabolism/pathology, Protein Binding, Protein Structure, Sadana Prabodh, Serum Albumin/chemistry/metabolism, Tertiary, Tumor

Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.

Elevated triglycerides (TG) contribute towards increased risk for cardiovascular disease. Lipoprotein lipase (LPL) is an enzyme that is responsible for the metabolism of core triglycerides of very-low density lipoproteins (VLDL) and chylomicrons in…

A novel Lipoprotein lipase (LPL) agonist rescues the enzyme from inhibition by angiopoietin-like 4 (ANGPTL4).

Lipoprotein lipase (LPL) is a key physiological regulator of triglycerides and atherosclerosis risk. Random screening identified a compound designated C10, showing greater LPL agonist activity than NO-1886, a known LPL agonist. Structure-activity…

Identification of a novel serum and glucocorticoid regulated kinase-1 (SGK1) ligand from virtual screening.

The serum and glucocorticoid regulated kinase-1 (SGK1) is part of the serine/threonine kinase family and has therapeutic potential in several neurodegenerative diseases such as ischemic stroke and Parkinson's disease. Here we use structure-based…

Tags: 2012, Binding Sites, Bioorganic & medicinal chemistry letters, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug Discovery, Geldenhuys Werner J, Humans, Immediate-Early Proteins/*antagonists & inhibitors/chemistry/metabolism, Ligands, Molecular Docking Simulation, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Protein Kinase Inhibitors/*chemistry/*pharmacology, Protein-Serine-Threonine Kinases/*antagonists & inhibitors/chemistry/metabolism, Sadana Prabodh, Talasila Phani K

Engineering triiodothyronine (T3) nanoparticle for use in ischemic brain stroke.

A potential means of pharmacological management of ischemic stroke is rapid intervention using potent neuroprotective agents. Thyroid hormone (T3) has been shown to protect against ischemic damage in middle cerebral artery occlusion (MCAO) model of…

Tags: 2013, Blood-brain barrier, Brain stroke, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Drug delivery and translational research, Geldenhuys Werner J, Mdzinarishvili Alexander, Nanoparticles, NEOMED College of Graduate Studies, NEOMED College of Pharmacy, Neuroprotection, Sadana Prabodh, Sutariya Vijaykumar, Talasila Phani K, Thyroid hormone

Disease Burden Among Individuals with Severe Mental Illness in a Community Setting.

This study examines the prevalence of comorbid physical health conditions within a community sample of individuals with severe mental illness (SMI), compares them to a matched national sample without SMI, and identifies which comorbidities create the…

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

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