Browse Items · NEOMED Bibliography Database

A multi-level modeling approach examining PTSD symptom reduction during prolonged exposure therapy: moderating effects of number of trauma types experienced, having an HIV-related index trauma, and years since HIV diagnosis among

People living with HIV (PLWH) have extensive interpersonal trauma histories and higher rates of posttraumatic stress disorder (PTSD) than the general population. Prolonged exposure (PE) therapy is efficacious in reducing PTSD across a variety of…

Tags: *HIV/AIDS, *prolonged exposure therapy, *PTSD, *trauma history, 2017, Adult, AIDS care, Boarts Jessica M, Ciesla Jeffrey A, Coleman Jennifer A, Delahanty Douglas L, Descriptive Statistics, Feeny Norah C, Female, HIV Infections/*psychology, HIV-Infected Patients – Psychosocial Factors, Human, Humans, Implosive Therapy/*methods, Jones Tracy, Junglen Angela G, LONGITUDINAL method, Male, Middle Aged, Pacella Maria L, Post-Traumatic – Symptoms, Post-Traumatic – Therapy, POST-traumatic stress disorder, Post-Traumatic/diagnosis/*psychology/*therapy, Prospective Studies, Psychological/*psychology/therapy, PSYCHOLOGY of HIV-positive people, Smith Brian C, Stress, Stress Disorders, Time, Time Factors, Trauma – Classification, Trauma – History, TREATMENT effectiveness, TREATMENT of post-traumatic stress disorder, Treatment Outcome, Treatment Outcomes – Evaluation, United States, WOUNDS & injuries – Classification, WOUNDS & injuries – History

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

A new dosing paradigm: high-dose, short-course fluoroquinolone therapy for community-acquired pneumonia.

The goals of optimal antimicrobial therapy are to treat infection effectively, to improve the clinical condition of the patient, and to prevent the emergence of resistant bacterial strains. For ideal drug usage the World Health Organization…

Tags: 2003, Clinical cornerstone, Community-Acquired Infections/*drug therapy, Department of Internal Medicine, File Thomas M Jr, Fluoroquinolones/*administration & dosage/pharmacology/therapeutic use, Humans, NEOMED College of Medicine, Ofloxacin/administration & dosage/pharmacology/therapeutic use, Pneumococcal/*drug therapy, Pneumonia, Safety, Time Factors, Treatment Outcome

A note regarding problems with interaction and varying block sizes in a comparison of endotracheal tubes.

A randomized clinical experiment to compare two types of endotracheal tubes utilized a block design where each of the six participating anesthesiologists performed tube insertions for an equal number of patients for each type of tube. Five…

Tags: *Randomized Controlled Trials as Topic, *Research Design, 2014, Algorithms, Anesthesiology/*methods, Computational and mathematical methods in medicine, Data Interpretation, Einsporn Richard L, Humans, Intratracheal/*instrumentation, Intubation, Jia Zhenyu, Models, Sample Size, Statistical, Treatment Outcome

A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice.

OBJECTIVES: Breast cancer-related lymphedema (BCRL) represents a major complication of breast cancer treatment, impacting the quality of life for breast cancer survivors that develop it. The purpose of this review is to evaluate the literature…

Adapting cognitive behavioral therapy for psychosis for case managers: increasing access to services in a community mental health agency.

OBJECTIVE: The purpose of this article is twofold: (a) to describe the adaptation of an evidence-based practice and, (b) using a dissemination framework, to describe the process of implementing the practice at a community mental health agency.…

Tags: *Community Mental Health Services, *Diffusion of Innovation, *Health Services Accessibility, 2014, Adult, Case Management, Case Managers, Cognitive Behavioral Therapy/education/*methods, Cognitive Therapy – Methods, collaboration, Community Mental Health Services – United States, Cooperative Behavior, Department of Psychiatry, Evidence-Based, Evidence-Based Practice/education/methods, Female, Human, Humans, Inservice Training, Interinstitutional Relations, Male, Montesano Vicki L, Munetz Mark R, NEOMED College of Medicine, Pelton Jeremy R, Pilot Studies, Professional Practice, Program Implementation – Methods, Psychiatric rehabilitation journal, Psychotic Disorders/*therapy, Questionnaires, Scales, Schizophrenia – Rehabilitation, Schizophrenia/*therapy, Sivec Harry J, Staff Development, Thematic Analysis, Treatment Outcome, Turkington Douglas, United Kingdom, United States

An institutional series and contemporary review of bacterial spinal epidural abscess: current status and future directions.

OBJECT: Over the past decade, the incidence of bacterial spinal epidural abscess (SEA) has been increasing. In recent years, studies on this condition have been rampant in the literature. The authors present an 11-year institutional experience with…

An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.

RATIONALE: Preclinical studies indicate that adult stem cells induce tissue repair by activating endogenous stem cells through the stromal cell-derived factor-1:chemokine receptor type 4 axis. JVS-100 is a DNA plasmid encoding human stromal…

Antitumor efficacy and tolerability of systemically administered gallium acetylacetonate-loaded gelucire-stabilized nanoparticles.

The widespread clinical success with most gallium compounds in cancer therapy is markedly hampered by lack of tumor specific accumulation, poor tumor permeability and undesirable toxicity to healthy tissues. The aim of this work was to investigate…

Appendicitis in the elderly: a change in the laparoscopic era.

BACKGROUND: Appendicitis in elderly patients is associated with significant morbidity and mortality. Early and correct diagnosis together with minimally invasive surgery can lead to more favorable outcomes than occurred in the prelaparoscopic era.…

Assessment of time to clinical response, a proxy for discharge readiness, among hospitalized patients with community-acquired pneumonia who received either ceftaroline fosamil or ceftriaxone in two phase III FOCUS trials.

The primary driver of health care costs for patients with community-acquired pneumonia (CAP) is the hospital length of stay (LOS). Unfortunately, hospital LOS comparisons are difficult to make from phase III CAP trials because of their structured…

Can aggressive treatment of diabetic foot infections reduce the need for above-ankle amputation?

We retrospectively evaluated the charts of 112 patients with diabetic foot infection to determine if early aggressive surgical intervention improves outcome. All patients were classified into two groups on the basis of the timing of surgical…

Carboplatin and paclitaxel for the treatment of advanced or recurrent endometrial cancer.

OBJECTIVE: The purpose of this study was to determine the activity and toxicity of carboplatin and paclitaxel (taxol) in the treatment of advanced or recurrent endometrial cancer. STUDY DESIGN: This was a retrospective review of 18 consecutive…

Cardiopulmonary resuscitation in the hospitalized patient: impact of system-based variables on outcomes in cardiac arrest.

BACKGROUND: A better understanding of the factors affecting the outcome of inpatient cardiopulmonary resuscitation (CPR) is crucial in making key clinical decisions. We aim to study the impact of various patient-related and hospital-related variables…

Catastrophic chest pain: blinded by cardiopulmonary disease.

A 53-year-old man with a history of diabetic foot ulcer, osteomyelitis, coronary artery disease, hypertension and hyperlipidaemia, presented with chest pain of 3 weeks duration. Eleven days earlier, the patient had had a drug-eluting stent (DES)…

Cholesteatoma of the maxillary sinus: a case report and review of the literature.

Cholesteatoma is a relatively common disease entity within the middle ear cavity, but it is rarely found in the paranasal sinuses. We describe a rare case of cholesteatoma in the maxillary sinus of an elderly man presenting with recurrent sinus…

Tags: 2015, Aged, American journal of otolaryngology, Cholesteatoma/*diagnosis/*surgery, Endoscopy/methods, Follow-Up Studies, Humans, Josephson Jordan S, Male, Maxillary Sinus/*pathology, Nasal Obstruction/diagnosis/etiology, Paranasal Sinus Diseases/*diagnosis/*surgery, Rare Diseases, Recurrence, Sinusitis/diagnosis/etiology, Sozansky Jeanie, Treatment Outcome

Clinical efficacy of newer agents in short-duration therapy for community-acquired pneumonia.

Streptococcus pneumoniae, the most important respiratory tract pathogen implicated in community-acquired pneumonia (CAP), is becoming increasingly resistant in vitro to the beta -lactams and macrolides, and fluoroquinolone resistance has been…

Tags: 2004, Anti-Infective Agents/*therapeutic use, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/*drug therapy/microbiology, Department of Internal Medicine, File Thomas M Jr, Humans, NEOMED College of Medicine, Pneumonia/*drug therapy/microbiology, Streptococcus pneumoniae/drug effects/isolation & purification, Treatment Outcome

Clinical implications of 750 mg, 5-day levofloxacin for the treatment of community-acquired pneumonia.

OBJECTIVE: To evaluate the time to symptom resolution and i.v.-to-p.o. transition in community-acquired pneumonia (CAP) patients treated with 750 mg or 500 mg levofloxacin. RESEARCH DESIGN: A retrospective, subset analysis of a multicenter,…

Cognitive behavioral therapy for psychosis in clinical practice.

Across two continents, Cognitive-Behavioral Therapy for Psychosis (CBT-P) has been endorsed as an adjunctive treatment for individuals who experience persistent positive symptoms of schizophrenia. The moderate effect sizes reported in early studies…

Complications and Perioperative Management of Patients Undergoing Thoracic Endovascular Aortic Repair.

Endovascular treatments have become increasingly common for patients with a variety of thoracic aortic pathologies. Although considered less invasive than traditional open surgical approaches, they are nonetheless complex procedures. Patients undergo…

Contrast-enhanced ultrasound detection and treatment guidance in a renal transplant patient with renal cell carcinoma.

Contrast-enhanced ultrasonography (CEUS) is an imaging modality that shows promise in the detection and characterization of renal masses, as well as treatment through CEUS-guided percutaneous radiofrequency ablation. These techniques may be…

Conversations on psoriasis–what patients want and what physicians can provide: a qualitative look at patient and physician expectations.

BACKGROUND: The role of the patient-physician relationship is a key issue in the management of lifelong, chronic conditions such as psoriasis, with each side bringing different perspectives. OBJECTIVE: To explore areas of congruence and disconnection…

Tags: *Attitude of Health Personnel, *Communication, *Patient Satisfaction, *Physician-Patient Relations, 2010, Dermatology/*organization & administration, Feldman Steven R, Humans, Kurkowski David, Psoriasis/complications/psychology/*therapy, The Journal of dermatological treatment, Treatment Outcome, Uhlenhake Elizabeth E

Dactylitis: implications for clinical practice.

OBJECTIVES: To assess the specificity of dactylitis for the diagnosis of spondyloarthropathy, sarcoidosis, and gout; and to characterize dactylitis specifically associated with gout. METHODS: Dactylitis was prospectively assessed among all…

Defects of pars interarticularis in athletes: a protocol for nonoperative treatment.

The purpose of this study was to report the results of a specific treatment protocol for athletes with spondylolysis or spondylolisthesis of the lumbar spine. A retrospective study with recent follow-up was performed on 82 patients treated with…

Derivation and external validation of a simple risk tool to predict 30-day hospital readmissions after transcatheter aortic valve replacement.

AIMS: Patients undergoing transcatheter aortic valve replacement (TAVR) possess a higher risk of recurrent healthcare resource utilisation due to multiple comorbidities, frailty, and advanced age. We sought to devise a simple tool to identify TAVR…

Discoid lateral meniscus.

Tags: 1999, Child, Eilert R E, Fleissner P R, Humans, Magnetic Resonance Imaging, Menisci, Radiography, The American journal of knee surgery, Tibial/*abnormalities/anatomy & histology/diagnostic imaging/surgery, Treatment Outcome

Does preoperative rofecoxib (Vioxx) decrease postoperative pain with laparoscopic cholecystectomy?

BACKGROUND: A prospective, randomized, double-blinded clinical trial was designed to study the effects of preemptive rofecoxib (Vioxx) analgesia in patients undergoing elective laparoscopic cholecystectomy. METHODS: One hundred-twenty patients were…

Dual-catheter covered stenting: a novel approach to the treatment of large coronary artery perforations.

Coronary perforation is an infrequent but potentially devastating complication of coronary intervention. Treatment of a broad-based perforation usually requires emergent pericardiocentesis and thoracotomy. We present a novel approach to closure of…

Effect of a standardized pharyngitis treatment protocol on use of antibiotics in a pediatric emergency department.

BACKGROUND: Pharyngitis is a common complaint in pediatric patients. If clinical parameters are used alone, bacterial pathogens will be wrongly implicated in many cases. A nonstandardized approach to the treatment of children with pharyngitis in an…

Effectiveness of a group exercise program in a long-term care facility: a randomized pilot trial.

OBJECTIVE: The purpose of this pilot was to determine whether a strength and flexibility program in frail long-term care facility (LTC) residents would result in improved function. DESIGN: A prospective, randomized, controlled, semicrossover trial…

Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: a randomized clinical trial.

BACKGROUND: Venous leg ulcers are a major cause of morbidity, economic loss, and decreased quality of life in affected patients. Recently, biomaterials derived from natural tissue sources have been used to stimulate wound closure. One such…

Efficacy and safety of ustekinumab and etanercept for the treatment of psoriasis.

IMPORTANCE OF THE FIELD: TNF-alpha inhibitors such as etanercept have been used for psoriasis for years. A fairly well defined efficacy and safety profile has developed. A new biologic agent, ustekinumab, an IL-12 and IL-23 inhibitor, has recently…

Endometrial rollerball ablation.

OBJECTIVE: To study a standardized technique for endometrial rollerball ablation and various methods of preoperative preparation. STUDY DESIGN: All patients had refractory symptomatic menorrhagia and previously failed conservative surgery and other…

Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia.

This 10-year retrospective study assessed the epidemiology and outcomes of patients with Fusobacterium bacteraemia (FB) at a tertiary-care hospital in the

Tags: *Hospital Mortality, 2013, 80 and over, Adult, Aged, Bacteremia – Mortality, Bacteremia – Physiopathology, Bacteremia/*mortality/physiopathology, Bonilla H F, Creatinine – Blood, Creatinine/blood, Epidemiology and infection, Female, Fusobacterium Infections – Mortality, Fusobacterium Infections – Physiopathology, Fusobacterium Infections/*mortality/physiopathology, Goldberg E A, Hewit M, Hospital Mortality, Hospitals, Human, Humans, Intensive Care Units – Statistics and Numerical Data, Intensive Care Units/statistics & numerical data, Length of Stay – Statistics and Numerical Data, Length of Stay/statistics & numerical data, Male, Middle Age, Middle Aged, Retrospective Design, Retrospective Studies, Risk Factors, Special – Statistics and Numerical Data, Tertiary Care Centers/*statistics & numerical data, Treatment Outcome, Treatment Outcomes, United States, United States/epidemiology, Venkat-Ramani T

Evaluation of factors associated with achieving glycemic control in a pharmacist-managed diabetes clinic.

The aim of this study was to identify factors that are associated with patients achieving goal A1c after 6 months in a pharmacist-managed diabetes clinic. This study is a descriptive, retrospective chart review of patients with type 2 diabetes…

Tags: 2014, Ambulatory Care, Ambulatory Care/organization & administration, American journal of therapeutics, Blood Glucose – Drug Effects, Blood Glucose/drug effects, Boros Melanie L, Department of Internal Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Diabetes Mellitus, Dose-Response Relationship, Drug, Female, Follow-Up Studies, Frazee Lawrence A, Glycated Hemoglobin A/metabolism, Glycosylated – Metabolism, Hemoglobin A, Human, Humans, Hypoglycemic Agents – Administration and Dosage, Hypoglycemic Agents – Therapeutic Use, Hypoglycemic Agents/administration & dosage/*therapeutic use, Insulin – Administration and Dosage, Insulin – Therapeutic Use, Insulin/administration & dosage/therapeutic use, Kostoff Matthew D, Male, Middle Age, Middle Aged, Moorman John M, NEOMED College of Medicine, NEOMED College of Pharmacy, Pharmaceutical Services/*organization & administration, Pharmacists – Administration, Pharmacists/*organization & administration, Pharmacy Service – Administration, Prospective Studies, Retrospective Design, Retrospective Studies, Social Work – Statistics and Numerical Data, Social Work/statistics & numerical data, Treatment Outcome, Treatment Outcomes, Type 2 – Drug Therapy, Type 2/*drug therapy

Final Two-Year Outcomes for the Sentry Bioconvertible Inferior Vena Cava Filter in Patients Requiring Temporary Protection from Pulmonary Embolism.

PURPOSE: To report final 2-year outcomes with the Sentry bioconvertible inferior vena cava (IVC) filter in patients requiring temporary protection against pulmonary embolism (PE). MATERIALS AND METHODS: In a prospective multicenter trial, the…

FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

OBJECTIVES: Ceftaroline, the active form of the prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated with community-acquired pneumonia (CAP), including Streptococcus pneumoniae and…

Tags: 2011, 80 and over, Aged, Bacteria, Bacteria/isolation & purification, Bacterial – Drug Therapy, Bacterial/*drug therapy, Ceftriaxone – Administration and Dosage, Ceftriaxone – Adverse Effects, Ceftriaxone/administration & dosage/adverse effects, Cephalosporins – Administration and Dosage, Cephalosporins – Adverse Effects, Cephalosporins/*administration & dosage/*adverse effects, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections/*drug therapy, Critchley Ian A, Department of Internal Medicine, Double-Blind Method, Double-Blind Studies, Eckburg Paul B, Female, File Thomas M Jr, Friedland H David, Human, Humans, Infusions, Intravenous, Lee Jon, Llorens Lily, Low Donald E, Male, Middle Age, Middle Aged, NEOMED College of Medicine, Pneumonia, RANDOMIZED controlled trials, Talbot George H, The Journal of antimicrobial chemotherapy, Thye Dirk A, Treatment Outcome, Treatment Outcomes

Focus issue on lumbar disc herniation: macro- and microdiscectomy.

This paper is based on a review, analysis, and discussion of the extensive literature on indications, technique, and complications of discectomy (macro and micro) for lumbar disc herniation. Outcomes for lumbar discectomy for disc herniation depend…

Tags: 1996, Adolescent, Adult, Diskectomy/*methods, Humans, Intervertebral Disc Displacement/*surgery, Lumbar Vertebrae/*pathology, McCulloch J A, Microsurgery/*methods, Middle Aged, Sciatica/etiology/therapy, Spine, Treatment Outcome

Gastric Lipoma: A Review of the Literature.

Gastric lipoma is a rare benign tumor of the stomach. The imaging characteristics are diagnostic because the lesion has fat attenuation on computed tomography and demonstrates characteristics of fat on magnetic resonance images. On ultrasound, the…

Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.

OBJECTIVES: Short-course therapy has been advocated for the treatment of community-acquired pneumonia (CAP). We compared the efficacy and safety of 5 and 7 day courses of gemifloxacin for outpatient treatment of mild-moderate CAP. PATIENTS AND…

Browse Items (123 total)