Browse Items · NEOMED Bibliography Database

US emergency department visits for hip fracture, 1992-2000.

BACKGROUND: Hip fracture is a significant injury for older persons. Little has been reported about emergency department (ED) care of these patients. OBJECTIVE: To characterize the management of older patients treated in the ED for hip fracture with…

Tags: 2004, 80 and over, Age Factors, Aged, Analgesia/statistics & numerical data, Camargo Carlos A Jr, Emergency Medical Services/*statistics & numerical data, Emond Jennifer A, European journal of emergency medicine : official journal of the European Society for Emergency Medicine, Female, Gerson Lowell W, Hip Fractures/diagnosis/*epidemiology/therapy, Humans, Male, Middle Aged, Sex Factors, United States/epidemiology

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

Spinous process osteotomies to facilitate lumbar decompressive surgery.

STUDY DESIGN: A technique for lumbar decompression using spinous process osteotomies is described, and the outcomes are studied prospectively. OBJECTIVE: To describe a technique that affords a wide exposure for decompression while minimizing damage…

Ventricular tachycardia in acute myocardial infarction: the role of hypophosphatemia.

The relationship between serum concentration of certain electrolytes and the pathogenesis of ventricular arrhythmia in myocardial infarction has been the subject of frequent review. The role of hypophosphatemia in the pathogenesis of arrhythmia in…

Parotid gland metastasis from renal cell carcinoma.

OBJECTIVE: To discuss the diagnosis and management of metastatic renal cell carcinoma presenting as a parotid mass by studying such cases. STUDY DESIGN: Retrospective review. METHODS: Identification of 24 previously reported cases of renal cell…

Tags: 2002, 80 and over, Aged, Biopsy, Carcinoma, Diagnosis, Differential, Female, Hlivko Thomas J, Humans, Kidney Neoplasms/*pathology, Needle, Park Youn W, Parotid Neoplasms/pathology/*secondary, Renal Cell/pathology/*secondary, Retrospective Studies, The Laryngoscope

Two-portal endoscopic carpal tunnel release: an outcome analysis of 333 hands.

Outcome data were collected on 239 patients who underwent endoscopic release of the transverse carpal ligament. The procedure was performed on 333 hands in 239 patients. All patients had failed to respond to nonoperative management for carpal tunnel…

Tags: 1998, 80 and over, Adult, Aged, Annals of plastic surgery, Carpal Tunnel Syndrome/physiopathology/*surgery, Davies B W, Endoscopy/*methods, Female, Fritz A M, Humans, Male, Middle Aged, Pennington G A, Treatment Outcome

Physiological Indices of Stress Prior to and Following Total Knee Arthroplasty Predict the Occurrence of Severe Post-Operative Pain.

OBJECTIVE: The severe pain and disability associated with osteoarthritis often motivate individuals to undergo arthroplastic surgery. However, a significant number of surgical patients continue to experience pain following surgery. Prior research has…

Tags: *Cardiovascular, *Cortisol, *Epinephrine, *Post-operative Pain, *Severity of Illness Index, *Stress, *Surgery, 2016, 80 and over, Aged, Arthroplasty, Catecholamines – Urine, Center for Epidemiological Studies Depression Scale, Cohort Studies, Cremeans-Smith Julie K, Data Analysis Software, Delahanty Douglas L, Descriptive Statistics, Effect Size, Female, Greene Kenneth, Human, Humans, Hydrocortisone – Urine, Knee, Knee/*adverse effects/psychology, Male, Middle Age, Middle Aged, Nonexperimental Studies, Ohio, Pain, Pain Measurement/methods, Pain medicine (Malden, Mass.), Physiological, Postoperative Pain – Risk Factors, Postoperative/*diagnosis/etiology/*psychology, Predictive Value of Tests, Prospective Studies, Psychological/complications/*diagnosis/*psychology, Regression, Replacement, Scales, Stress, Summated Rating Scaling, Treatment Outcome

FOCUS 1: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia.

OBJECTIVES: Ceftaroline, the active form of the prodrug ceftaroline fosamil, is a novel cephalosporin with bactericidal activity against important pathogens associated with community-acquired pneumonia (CAP), including Streptococcus pneumoniae and…

Tags: 2011, 80 and over, Aged, Bacteria, Bacteria/isolation & purification, Bacterial – Drug Therapy, Bacterial/*drug therapy, Ceftriaxone – Administration and Dosage, Ceftriaxone – Adverse Effects, Ceftriaxone/administration & dosage/adverse effects, Cephalosporins – Administration and Dosage, Cephalosporins – Adverse Effects, Cephalosporins/*administration & dosage/*adverse effects, Community-Acquired Infections – Drug Therapy, Community-Acquired Infections/*drug therapy, Critchley Ian A, Department of Internal Medicine, Double-Blind Method, Double-Blind Studies, Eckburg Paul B, Female, File Thomas M Jr, Friedland H David, Human, Humans, Infusions, Intravenous, Lee Jon, Llorens Lily, Low Donald E, Male, Middle Age, Middle Aged, NEOMED College of Medicine, Pneumonia, RANDOMIZED controlled trials, Talbot George H, The Journal of antimicrobial chemotherapy, Thye Dirk A, Treatment Outcome, Treatment Outcomes

Gemifloxacin once daily for 5 days versus 7 days for the treatment of community-acquired pneumonia: a randomized, multicentre, double-blind study.

OBJECTIVES: Short-course therapy has been advocated for the treatment of community-acquired pneumonia (CAP). We compared the efficacy and safety of 5 and 7 day courses of gemifloxacin for outpatient treatment of mild-moderate CAP. PATIENTS AND…

Can aggressive treatment of diabetic foot infections reduce the need for above-ankle amputation?

We retrospectively evaluated the charts of 112 patients with diabetic foot infection to determine if early aggressive surgical intervention improves outcome. All patients were classified into two groups on the basis of the timing of surgical…

SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.

BACKGROUND: Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. METHODS: A total of 863 adults with…

Tags: *clinical trial, *Community-acquired, *Pneumonia, *solithromycin, *Streptococcus pneumoniae, 2016, 80 and over, Administration, Adult, Aged, Anti-Bacterial Agents/*administration & dosage/adverse effects, Bacterial, Bacterial/diagnosis/*drug therapy/*microbiology, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Community-Acquired Infections/diagnosis/*drug therapy/*microbiology, Comorbidity, Das Anita F, Department of Internal Medicine, Drug Resistance, Female, Fernandes Prabhavathi, File Thomas M Jr, Fluoroquinolones/*administration & dosage/adverse effects, Gonong Joven Roque V, Humans, Intravenous, Jamieson Brian D, Keedy Kara, Macrolides/*administration & dosage/adverse effects, Male, Microbial Sensitivity Tests, Middle Aged, Moxifloxacin, NEOMED College of Medicine, Oldach David, Oral, Pneumonia, Rewerska Barbara, Sheets Amanda, Taylor David, Treatment Outcome, Triazoles/*administration & dosage/adverse effects, Vucinic-Mihailovic Violeta

Results of the promoting effective advance care planning for elders (PEACE) randomized pilot study.

The specific aim of the PEACE pilot study was to determine the feasibility of a fully powered study to test the effectiveness of an in-home geriatrics/palliative care interdisciplinary care management intervention for improving measures of…

Tags: *Quality of Life, 2014, 80 and over, Activities of Daily Living, advance care planning, Advance Care Planning/*organization & administration, Aged, Albanese Teresa H, Allen Kyle R, Case Management – Methods, Chi Square Test, College of Medicine, Community-Institutional Relations, Comparative Studies, Decision Making, Department of Family & Community Medicine, Department of Pharmaceutical Sciences, Department of Pharmacy Practice, Descriptive Statistics, Disease Management, Ertle Denise, Family, Female, Fosnight Susan M, Frail Elderly, Geriatric Assessment/methods, Hazelett Susan E, Health Promotion, Health Resource Utilization, Health Services for the Aged/organization & administration, Home Care Services/*organization & administration, Human, Humans, Interdisciplinary Communication, Kropp Denise J, Long Term Care, Long-Term Care/*organization & administration, Male, Medicaid – Ohio, Moore Pamela S, Multidisciplinary Care Team, NEOMED College of Medicine, NEOMED College of Pharmacy, Ohio, Outcomes (Health Care), Palliative Care, Palliative Care/organization & administration, Patient, Physicians, Pilot Projects, Pilot Studies – Ohio, Population health management, Program Evaluation, Psychological Tests, Quality of Life, Radwany Steven M, Random Assignment, Reference Values, Repeated Measures, Scales, Spiritual Care, T-Tests, Treatment Outcome

Integrated analysis of FOCUS 1 and FOCUS 2: randomized, doubled-blinded, multicenter phase 3 trials of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in patients with community-acquired pneumonia.

BACKGROUND: Ceftaroline, the active form of ceftaroline fosamil, is a broad-spectrum cephalosporin with bactericidal activity against pathogens causing community-acquired pneumonia (CAP), including Streptococcus pneumoniae. Ceftaroline was evaluated…

Clinical characteristics of Chlamydia pneumoniae infection as the sole cause of community-acquired pneumonia.

The clinical characteristics of 26 patients with community-acquired pneumonia due to Chlamydia pneumoniae as the only identified pathogen who required hospitalization were evaluated. Most patients (18) had reinfection based on serological results.…

Mindfulness as a predictor of positive reappraisal and burnout in standardized patients.

BACKGROUND: Standardized patients (SPs) portray emotionally intense roles that can have unintended deleterious effects including burnout. PURPOSE: This study explored SP characteristics that could serve as protective factors against these adverse…

The epidemiology of respiratory tract infections.

Respiratory tract infections (RTIs) are the most common, and potentially most severe, of infections treated by health care practitioners. Lower RTIs along with influenza, are the most common cause of death by infection in the United States. Risk…

The assessment and treatment of back and neck pain: an initial investigation in a primary care practice-based research network.

AIM: The purpose of this study was to conduct an exploratory examination of the current state of non-malignant acute and chronic back and neck pain assessment and management among primary care providers in a multi-site, practice-based research…

Geriatric Disaster Preparedness.

INTRODUCTION: The elderly population has proven to be vulnerable in times of a disaster. Many have chronic medical problems for which they depend on medications or medical equipment. Some older adults are dependent on caregivers for managing their…

Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia.

This 10-year retrospective study assessed the epidemiology and outcomes of patients with Fusobacterium bacteraemia (FB) at a tertiary-care hospital in the

Tags: *Hospital Mortality, 2013, 80 and over, Adult, Aged, Bacteremia – Mortality, Bacteremia – Physiopathology, Bacteremia/*mortality/physiopathology, Bonilla H F, Creatinine – Blood, Creatinine/blood, Epidemiology and infection, Female, Fusobacterium Infections – Mortality, Fusobacterium Infections – Physiopathology, Fusobacterium Infections/*mortality/physiopathology, Goldberg E A, Hewit M, Hospital Mortality, Hospitals, Human, Humans, Intensive Care Units – Statistics and Numerical Data, Intensive Care Units/statistics & numerical data, Length of Stay – Statistics and Numerical Data, Length of Stay/statistics & numerical data, Male, Middle Age, Middle Aged, Retrospective Design, Retrospective Studies, Risk Factors, Special – Statistics and Numerical Data, Tertiary Care Centers/*statistics & numerical data, Treatment Outcome, Treatment Outcomes, United States, United States/epidemiology, Venkat-Ramani T

Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

The efficacy of a new pharmacokinetically enhanced formulation of amoxycillin/clavulanate (AMX/CA) 2000/125 mg, twice daily, designed to provide adequate levels of amoxycillin over the 12-h dosing interval to eradicate penicillin-resistant…

Tags: *Treatment Outcome, 2002, 80 and over, Adolescent, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination/administration & dosage/*pharmacokinetics/pharmacology/*therapeutic use, Amoxicillin/adverse effects/therapeutic use, Bacterial, Bacterial/drug therapy/immunology, Bronchitis/drug therapy/microbiology, Combination/adverse effects/*therapeutic use, Department of Internal Medicine, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Drug Therapy, Female, File Thomas M Jr, Follow-Up Studies, Humans, International journal of antimicrobial agents, Jacobs Michael R, Male, Microbial Sensitivity Tests, Middle Aged, Multicenter Studies as Topic, NEOMED College of Medicine, Pneumonia, Poole Michael D, Respiratory Tract Infections/*drug therapy/metabolism/microbiology, Streptococcal Infections/*drug therapy/metabolism/microbiology, Streptococcus pneumoniae/*drug effects, Wynne Brian

Evaluation of the patient with seizures: an evidence based approach.

Statistics tell us that as many as 1 in 20 members of the population will suffer a seizure at some point in their lifetime, a figure which becomes even more likely if one lives to the age of 80. Thus, a careful evidence based approach to the patient…

Case finding for cognitive impairment in elderly emergency department patients.

STUDY OBJECTIVES: To determine the feasibility of a case-finding program for cognitive impairment in elderly emergency department patients, and to describe the prevalence of cognitive impairment in screened patients and identify factors associated…

Difficulty in predicting bacteremia in elderly emergency patients.

STUDY OBJECTIVES: To characterize the clinical presentation and identify factors predictive of bacteremia in elderly patients. DESIGN: Retrospective review of emergency department charts, hospital records, and microbiology reports. SETTING: Community…

Uterine problems discovered after presumed hysterectomy: the Manchester operation revisited.

BACKGROUND: The Manchester operation consists of amputation of the cervix, leading some patients to believe that they have undergone a hysterectomy. CASES: A 69-year-old woman with vaginal discharge proved to have a well-differentiated adenocarcinoma…

Tags: *Hysterectomy, 1997, 80 and over, Aged, Amputation/*methods, Cervix Uteri/*surgery, DeLancey J O, Devine J B, Diagnosis, Differential, Female, Hopkins M P, Humans, Obstetrics and gynecology, Uterine Diseases/*diagnosis/surgery, Uterine Prolapse/*surgery

Quality of life, symptoms and care needs in patients with persistent or recurrent platinum-resistant ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.

OBJECTIVES: The goals of treating recurrent platinum-resistant ovarian cancer are palliative, aimed at reducing symptoms and improving progression free survival. A prospective trial was conducted to determine the prevalence and severity of symptoms,…

Chemotherapy completion in elderly women with ovarian, primary peritoneal or fallopian tube cancer - An NRG oncology/Gynecologic Oncology Group study.

PURPOSE: A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline Instrumental Activities of Daily Living (IADL) score with ability to complete 4 cycles of first line…

Can ultrasound be used to predict malignancy in patients with a thyroid nodule and an indeterminate fine-needle aspiration biopsy?

PURPOSE: The purpose of this study was to evaluate whether ultrasonography is helpful in predicting malignancy in patients with a thyroid nodule and atypia/follicular lesion of undetermined significance (AFLUS). METHODS: All patients with a…

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

The utility of hair cortisol concentrations in the prediction of PTSD symptoms following traumatic physical injury.

RATIONALE: Although cortisol alterations have been associated with posttraumatic stress disorder (PTSD) and PTSD symptoms (PTSS), the direction of association is mixed. Cortisol which is measured in blood, saliva, or urine is subject to transient…

Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype.

Osteoarthritis (OA) is a degenerative cartilage disease with varying degrees of severity within a given joint. The purpose of this study was to define a sampling procedure for comparing human minimal and advanced OA cartilage in the same patient and…

Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: a randomized clinical trial.

BACKGROUND: Venous leg ulcers are a major cause of morbidity, economic loss, and decreased quality of life in affected patients. Recently, biomaterials derived from natural tissue sources have been used to stimulate wound closure. One such…

Selective lateral compartment neck dissection for thyroid cancer.

BACKGROUND: Compartment-oriented lymph node dissection in patients with thyroid cancer and macroscopic lymph node metastases reduces recurrence and improves survival. However, the extent of lymph node dissection remains controversial. The purpose of…

Phase I/II prospective trial of autologous platelet tissue graft in gynecologic surgery.

STUDY OBJECTIVE: To perform the original phase I/II trial of autologous platelet tissue graft in gynecologic surgery to evaluate toxicity and efficacy on decreasing pain. DESIGN: Prospective nonrandomized trial (Canadian Task Force classification…

Feasibility of the Maylard transverse incision for ovarian cancer cytoreductive surgery.

The vast majority of abdominal incisions used in gynecologic surgery are either transverse or vertical midline. The advantages of a vertical midline incision are considered to be rapid abdominal entry and increased exposure to the abdomen and pelvis.…

Tags: 2007, 80 and over, Aged, Fanning James, Feasibility Studies, Female, Flora Robert F, Gynecologic Surgical Procedures/adverse effects/*methods, Humans, Journal of minimally invasive gynecology, Middle Aged, Ovarian Neoplasms/*surgery, Pruett Allison, Reoperation, Tissue Adhesions/*etiology

PTSD symptom severity and psychiatric comorbidity in recent motor vehicle accident victims: a latent class analysis.

We conducted a latent class analysis (LCA) on 249 recent motor vehicle accident (MVA) victims to examine subgroups that differed in posttraumatic stress disorder (PTSD) symptom severity, current major depressive disorder and alcohol/other drug use…

Plication augmentation of the modified Hummelsheim procedure for treatment of large-angle esotropia due to abducens nerve palsy and type 1 Duane syndrome.

BACKGROUND: Multiple procedures have been described to treat a large-angle esodeviation with an associated abduction deficit. We report a plication augmentation of the Hummelsheim procedure for the management of esotropia and severe abduction deficit…

Tags: *Ophthalmologic Surgical Procedures, 2015, 80 and over, Abducens Nerve Diseases/complications/physiopathology/*surgery, Adolescent, Adult, Aged, Binocular/physiology, Botulinum Toxins, Child, Cochran Megan, Duane Retraction Syndrome/complications/physiopathology/*surgery, El Sahn Mahmoud, Esotropia/etiology/physiopathology/*surgery, Eye Movements/physiology, Female, Granet David B, Hertle Richard W, Humans, Injections, Intramuscular, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, Khayali Salma, Kinori Michael, Male, Middle Aged, Miller Kyle E, Neuromuscular Agents/administration & dosage, Oculomotor Muscles/drug effects/physiopathology/*surgery, Patil Preeti A, Preschool, Retrospective Studies, Robbins Shira L, Suture Techniques, Tendon Transfer, Type A/administration & dosage, Vision, Young Adult

Hemipelvic amputations for recalcitrant pelvic osteomyelitis.

OBJECTIVE: To evaluate the outcome of recalcitrant deep pelvic infection that required a hemipelvic amputation. STUDY DESIGN: Retrospective cohort. SETTING: Tertiary referral centre; Level I trauma. PATIENTS: There were 20 patients with an infection…

Retrospective review of biopsy results following percutaneous fixation of vertebral compression fractures.

BACKGROUND: Percutaneous vertebral body fixation has been found to provide pain relief and restoration of function for patients with compression fractures. Despite the prevalence of osteoporosis, there are a variety of aetiologies, such as lymphoma,…

Outcomes of modular proximal femoral replacement in the treatment of complex proximal femoral fractures: a case series.

BACKGROUND: The treatment of complex femur fractures poses a significant challenge. Even with current advancements and the various implements available for the fixation of femoral fractures, results are often disappointing. This study sought to…

Crisis intervention team officer dispatch, assessment, and disposition: Interactions with individuals with severe mental illness.

The Crisis Intervention Team (CIT) model is a specialized police response program for people in a mental illness crisis. We analyzed 2174 CIT officers' reports from one community, which were completed during a five year period. These officers'…

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