Browse Items · NEOMED Bibliography Database

Epigenetic regulation in diabetes-associated oxidative stress and myocardial dysfunction.

Tags: *Epigenesis, *Oxidative Stress, 2018, Cardiomyopathies, Chilian William M, Department of Integrative Medical Sciences, Dong Feng, Genetic, Humans, International journal of cardiology, NEOMED College of Medicine, Yin Liya

Introducing a curriculum in ethics and professionalism for dermatology residencies.

There is general agreement on what constitutes ethical reasoning and professional behavior, but standardized methods to teach these skills in dermatology residency are currently unavailable. We introduce a model curriculum designed to impart the…

A Technique to Provide Enhanced Visualization For Suture Cutting In Dermatologic Surgery.

Tags: 2018, dermatologic surgery, Hocker Thomas L H, Journal of the American Academy of Dermatology, Neill Brett C, Skin, Stevens Jason, suture, Tarantino Isadore S, technique

Low thigh muscle mass is associated with coronary artery stenosis among

BACKGROUND: HIV-infected individuals are at increased risk for both sarcopenia and cardiovascular disease. Whether an association between low muscle mass and subclinical coronary artery disease (CAD) exists, and if it is modified by HIV serostatus,…

Tags: *Computed Tomography Angiography, *Tomography, 2018, Aged, Atherosclerotic, Body Composition, Brown Todd T, Budoff Matthew J, Chi-Square Distribution, Coronary Angiography/*methods, Coronary Artery Disease/*diagnostic imaging/epidemiology/pathology, Coronary artery stenosis, Coronary atherosclerosis, Coronary Stenosis/*diagnostic imaging/epidemiology/pathology, Coronary Vessels/*diagnostic imaging/pathology, Cross-Sectional Studies, Guallar Eliseo, HIV Infections/diagnosis/*epidemiology, HIV-Infection, Humans, Jacobson Lisa P, Journal of cardiovascular computed tomography, Koletar Susan L, Korada Sai Krishna C, Male, Margolick Joseph B, Michos Erin D, Middle Aged, Multivariate Analysis, Muscle, Muscle mass, Odds Ratio, Palella Frank J Jr, Plaque, Post Wendy S, Predictive Value of Tests, Prevalence, Prospective Studies, Risk Factors, Sarcopenia, Sarcopenia/*diagnostic imaging/epidemiology/physiopathology, Saxena Ankita, Skeletal/*diagnostic imaging/physiopathology, Thigh, Tibuakuu Martin, United States/epidemiology, Witt Mallory D, X-Ray Computed, Zhao Di

Obesity and Binge Drinking: Two Hits Driving Liver Fibrosis Progression?

Tags: 2018, Cellular and molecular gastroenterology and hepatology, Department of Pharmaceutical Sciences, NEOMED College of Pharmacy, You Min

Ulcerative livedoid vasculopathy responding to clopidogrel.

Tags: 2018, antiplatelet, atrophie blanche, Chong Benjamin F, Clopidogrel, ILD, interstitial lung disease, intravenous immunoglobulin, IVIG, JAAD case reports, Kunzler Elaine, livedoid vasculopathy, LV, ulcers

During the Emergency Department Evaluation of a Well-Appearing Neonate with Fever, Should Empiric Acyclovir Be Initiated?

BACKGROUND: Herpes simplex virus (HSV) infection represents significant morbidity and mortality in the neonatal period. Although clear guidelines exist on the evaluation and management of the otherwise well-appearing febrile neonate pertaining to…

Tags: 2018, acyclovir, Acyclovir – Therapeutic Use, Acyclovir/*therapeutic use, Antiviral Agents – Therapeutic Use, Antiviral Agents/therapeutic use, Bruno Eric, Cheng David, Decision Making, Department of Emergency Medicine, febrile neonate, Female, Ferrans and Powers Quality of Life Index, Fever – Etiology, Fever/etiology, Guidelines as Topic/standards, Herpes Simplex – Complications, Herpes Simplex – Diagnosis, Herpes Simplex – Drug Therapy, herpes simplex virus, Herpes Simplex/complications/diagnosis/*drug therapy, Herpesviruses, HSV, Humans, Infant, Infectious – Diagnosis, Infectious/diagnosis, Male, NEOMED College of Medicine, neonatal fever, Newborn, Pillus David, Pokrajac Nicholas, Practice Guidelines – Standards, Pregnancy Complications, Scales, Simplexvirus/pathogenicity, The Journal of emergency medicine, Vilke Gary

DISC: Describing Infections of the Spine treated with Ceftaroline.

OBJECTIVES: Infections of the spine lead to considerable morbidity and a high cost to the global healthcare system. Currently, evidence for using ceftaroline, an advanced-generation cephalosporin active against methicillin-resistant Staphylococcus…

Tags: 2018, Bonomo Robert A, Burdette Steven D, Ceftaroline, Department of Internal Medicine, Discitis, epidural abscess, Haller Nairmeen Awad, Horattas Sophia, Journal of global antimicrobial resistance, Mangira Caroline, MRSA, NEOMED College of Medicine, Salata Robert A, Vertebral osteomyelitis, Watkins Richard R, Yendewa George

Dietary signals in the premolar dentition of primates.

Dietary adaptations specific to the premolar row remain largely undocumented across primates. This study examines how relative premolar size varies among broad dietary groups (i.e., folivores, frugivores, insectivores, hard-object feeders) using a…

Tags: 2018, Adaptation, Baj Luisa M, Burns Maegan C, Campbell Ryan M, Feeding, Functional morphology, Journal of human evolution, Mastication, Price Mia S, Scott Jeremiah E, Sykes Jaime D, Teeth, Vinyard Christopher J

Glycoprotein Nonmelanoma Clone B Regulates the Crosstalk between Macrophages and Mesenchymal Stem Cells toward Wound Repair.

The process of wound repair requires the coordinated participation of multiple types of cells, which are sequentially recruited during the healing process. In response to tissue injury, both macrophages and mesenchymal stem cells (MSCs) are recruited…

Tags: 2018, Alboslemy Talib, Department of Anatomy & Neurobiology, Kim Min-Ho, NEOMED College of Medicine, Safadi Fayez, The Journal of investigative dermatology, Yu Bing

Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes.

OBJECTIVE: Mitochondrial dysfunction, oxidative stress and chondrocyte death are important contributors to the development and pathogenesis of osteoarthritis (OA). In this study, we determined the expression and role of Parkin in the clearance of…

Tags: 2018, Ahmad I, Ansari M Y, Chondrocytes, Department of Anatomy & Neurobiology, Haqqi T M, Khan N M, Mitochondrial dysfunction, NEOMED College of Medicine, Osteoarthritis, Osteoarthritis and cartilage, Parkin, ROS

Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?

Reversal of antiplatelet therapy with platelet transfusion in traumatic intracranial hemorrhage remains controversial. Several studies have examined this topic but few have investigated whether the timing of transfusion affects outcomes. Patients…

Patterns of co-occurring addictions, posttraumatic stress disorder, and major depressive disorder in detoxification treatment seekers: Implications for improving detoxification treatment outcomes.

BACKGROUND AND OBJECTIVES: Poly-substance use and psychiatric comorbidity are common among individuals receiving substance detoxification services. Posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) are the most common…

Tags: 2018, Anderson RaeAnn E, Boros Alec P, Delahanty Douglas L, Detoxification, Hruska Bryce, Journal of substance abuse treatment, Latent class analysis, Polysubstance use, PTSD, Richardson Christopher J, Treatment

Safe Readministration of Intravenous Thrombolysis in Recurrent Basilar Thrombosis.

We report a patient who had recurrence of stroke in the basilar artery territory because of repeat thrombosis, and was administered intravenous recombinant tissue plasminogen activator (IV-rtPA) twice within a span of 3 weeks without any adverse…

Tags: 2018, Aged, Basilar Artery, Basilar Artery – Drug Effects, Basilar Artery – Physiopathology, Basilar Artery/diagnostic imaging/*drug effects/physiopathology, Cerebral Angiography – Methods, Cerebral Angiography/methods, Computed Tomography Angiography, Department of Internal Medicine, Drug Administration Schedule, Fibrinolytic Agents – Administration and Dosage, Fibrinolytic Agents – Adverse Effects, Fibrinolytic Agents/*administration & dosage/adverse effects, Humans, Infusions, Intracranial Thrombosis, Intracranial Thrombosis – Drug Therapy, Intracranial Thrombosis – Physiopathology, Intracranial Thrombosis/diagnostic imaging/*drug therapy/physiopathology, Intravenous, Itrat Ahmed, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Khan Alina, Magnetic Resonance Imaging, Male, medication safety, NEOMED College of Medicine, Recombinant Proteins – Administration and Dosage, Recombinant Proteins/administration & dosage, Recurrence, recurrent stroke, Repeat Procedures, Retreatment, thrombolysis, Thrombolytic Therapy – Adverse Effects, Thrombolytic Therapy – Methods, Thrombolytic Therapy/adverse effects/*methods, Thrombosis, Time Factors, Tissue Plasminogen Activator – Administration and Dosage, Tissue Plasminogen Activator – Adverse Effects, Tissue Plasminogen Activator/*administration & dosage/adverse effects, Treatment Outcome, Treatment Outcomes

Editorial Comment.

Tags: 2018, Barr Richard G, The Journal of urology

Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR.

OBJECTIVES: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, we aim to determine the impact of pharmacological activation of…

The effect of manganese exposure in Atp13a2-deficient mice.

Loss of function mutations in the P5-ATPase ATP13A2 are associated with Kufor-Rakeb Syndrome and Neuronal Ceroid Lipofuscinosis. While the function of ATP13A2 is unclear, in vitro studies suggest it is a lysosomal protein that interacts with the…

Evidence of Wnt/beta-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease.

Low bone mineral density (BMD) is a significant comorbidity in Alzheimer's disease (AD) and may reflect systemic regulatory pathway dysfunction. Low BMD has been identified in several AD mouse models selective for amyloid-beta or tau pathology, but…

A three-dimensional digital neurological atlas of the mustached bat (Pteronotus parnellii).

Substantial knowledge of auditory processing within mammalian nervous systems emerged from neurophysiological studies of the mustached bat (Pteronotus parnellii). This highly social and vocal species retrieves precise information about the velocity…

Nodes of Ranvier in Glaucoma.

Retinal ganglion cell axons of the DBA/2J mouse model of glaucoma, a model characterized by extensive neuroinflammation, preserve synaptic contacts with their subcortical targets for a time after onset of anterograde axonal transport deficits, axon…

Tags: *Axonopathy, *axons, *neurodegeneration, *neurofilament, *node of Ranvier, *superior colliculus, 2018, Crish S D, Dengler-Crish C M, Department of Pharmaceutical Sciences, Meier J, NEOMED College of Pharmacy, Neuroscience, Plyler E S, Smith M A

An N of one.

Tags: 2018, Department of Family & Community Medicine, NEOMED College of Medicine, O'Donnell Elizabeth A, Patient education and counseling

Stable isotope-based flux studies in nonalcoholic fatty liver disease.

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is associated with the worldwide epidemics of obesity, diabetes and cardiovascular diseases. NAFLD ranges from benign fat accumulation in the liver (steatosis) to…

Tags: *Citric acid cycle, *Fatty acid oxidation, *Fibrosis, *NAFLD, *Oxidative Stress, *Stable isotopes, 2018, Animals, Department of Pharmaceutical Sciences, Humans, Isotopes/metabolism, Kasumov Takhar, Mass Spectrometry/*methods, McCullough Arthur, NEOMED College of Pharmacy, Non-alcoholic Fatty Liver Disease/*metabolism, Pharmacology & therapeutics, Previs Stephen

Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics.

Osteoarthritis (OA) is the most common joint disease and the leading cause of chronic disability in middle-aged and older populations worldwide. The development of disease modifying therapy for OA is in its infancy largely because the regulatory…

Tags: *DNA methylation, *Epigenetics, *HDACs, *lncRNA, *miRNA, *OSTEOARTHRITIS, 2018, Animals, Department of Anatomy & Neurobiology, Epigenesis, Genetic, Haqqi Tariq M, Histone Deacetylase Inhibitors/*therapeutic use, Humans, Khan Nazir M, NEOMED College of Medicine, Osteoarthritis/*drug therapy/*genetics, Pharmacological research

A rapid UPLC-MS/MS assay for eicosanoids in human plasma: Application to evaluate niacin responsivity.

A rapid and sensitive method using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed to simultaneously quantify hydroxyeicosatetraenoic (HETE), dihydroxyeicosatrienoic (DiHETrE), epoxyeicosatrienoic acid…

Tags: 2018, Anderson Kacey B, Arachidonic Acid, Eicosanoids, Mass spectrometry, Messamore Erik, Miller Tricia M, Niacin, Plasma, Poloyac Samuel M, Prostaglandins, leukotrienes, and essential fatty acids, Prostanoids, Schizophrenia, Ultra performance liquid chromatography, UPLC-MS/MS, Waddell Brooke L, Yao Jeffrey K

The niacin response biomarker as a schizophrenia endophenotype: A status update.

Increasingly, it is recognized that the behavioral syndrome of schizophrenia is not a unitary disease with a single underlying cause. Rather, it may have several possible etiologies, and its symptoms may arise from multiple causes. Such heterogeneity…

Tags: 2018, Biomarker, Endophenotype, Messamore Erik, Niacin, Prostaglandins, leukotrienes, and essential fatty acids, Schizophrenia, vasodilation

Gender and age make no difference in the re-irradiation of painful bone metastases: A secondary analysis of the NCIC CTG SC.20 randomized trial.

BACKGROUND AND PURPOSE: Patient's gender and age may influence physicians in prescribing palliative radiotherapy. The purpose of this secondary analysis of the National Cancer Institute of Canada Clinical Trials Group Symptom Control Trial SC.20 was…

Tags: *Age, *Bone metastases, *Gender, *Pain response, *Quality of Life, *Radiotherapy, *Re-irradiation, 2018, Age Factors, Aged, Babington Scott, Bone Neoplasms/physiopathology/*radiotherapy/*secondary, Brundage Michael, Cancer Pain/etiology/*radiotherapy, Chow Edward, Chow Ronald, Demas William F, Ding Keyue, Female, Ganesh Vithusha, Hartsell William F, Hoskin Peter, Humans, Male, Meyer Ralph M, Middle Aged, Nabid Abdenour, Pain Measurement, Palliative Care/methods/statistics & numerical data, Patient Reported Outcome Measures, Physicians'/*statistics & numerical data, Practice Patterns, Quality of Life, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Re-irradiation, Roos Daniel, Sex Factors, van Acht Manouk, van der Linden Yvette M, Wanders Rinus, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Zhu Liting

Is resection for solitary

Tags: 2018, Surgery, Tsai Allen J

Quinone and nitrofurantoin redox cycling by recombinant cytochrome b5 reductase.

NADH cytochrome b5 reductase mediates electron transfer from NADH to cytochrome b5 utilizing flavin adenine dinucleotide as a redox cofactor. Reduced cytochrome b5 is an important cofactor in many metabolic reactions including cytochrome

Tags: 2018, Aleksunes Lauren M, Cytochrome b5, Department of Pharmaceutical Sciences, Free radicals, Fussell Karma C, Heck Diane E, Jan Yi-Hua, Laskin Debra L, Laskin Jeffrey D, Mishin Vladimir, NEOMED College of Pharmacy, reactive oxygen species, Redox cycling, Richardson Jason R, Szilagyi John T, Toxicology and applied pharmacology, Wang Yun, Yang Shaojun

Trends in the Authorship of Peer Reviewed Publications in the Urology Literature.

INTRODUCTION: We evaluated the authorship count of all original research and review articles published in prominent Urology journals to trend patterns in authorship over the last decade. Secondarily, we evaluated bibliometric assessments and sought…

Tags: 2018, Academic urology, An Julie Y, Baiocco Joseph A, Citations, H-index, Impact factor, Journals, Manuscripts, Rais-Bahrami Soroush, Urology practice

Sexual harassment in the work place: Its impact on gynecologic oncology and women's health.

For the last few months, media and news outlets have exposed prominent professionals in many settings who have taken advantage of their status of power and influence to engage in sexual harassment and discrimination in the workplace. In medicine,…

Tags: *Discrimination, *Gynecologic oncology, *Sexual harassment, *women's health, 2018, Female, Female/etiology/*psychology/therapy, Genital Neoplasms, Gynecologic oncology, Health Personnel, Humans, Karlan Beth Y, Male, Occupational Stress/etiology/psychology, Sexism, Sexual Harassment/*psychology, von Gruenigen Vivian E, Workplace

Quality of life, symptoms and care needs in patients with persistent or recurrent platinum-resistant ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.

OBJECTIVES: The goals of treating recurrent platinum-resistant ovarian cancer are palliative, aimed at reducing symptoms and improving progression free survival. A prospective trial was conducted to determine the prevalence and severity of symptoms,…

Mitochondrial complex I in the post-ischemic heart: reperfusion-mediated oxidative injury and protein cysteine sulfonation.

A serious consequence of ischemia-reperfusion injury (I/R) is oxidative damage leading to mitochondrial dysfunction. Such I/R-induced mitochondrial dysfunction is observed as impaired state 3 respiration and overproduction of O2(-). The cascading ROS…

Tags: 2018, Chen Chwen-Lih, Chen Yeong-Renn, Complex I, Department of Family & Community Medicine, Department of Integrative Medical Sciences, Journal of molecular and cellular cardiology, Kang Patrick T, Lin Paul, Mitochondrial dysfunction, Myocardial ischemia and reperfusion, NEOMED College of Medicine, Protein cysteine sulfonation, Protein Structure, Zhang Liwen, Zweier Jay L

d2ome, Software for in Vivo Protein Turnover Analysis Using Heavy Water Labeling and LC-MS, Reveals Alterations of Hepatic Proteome Dynamics in a Mouse Model of NAFLD.

Metabolic labeling with heavy water followed by LC-MS is a high throughput approach to study proteostasis in vivo. Advances in mass spectrometry and sample processing have allowed consistent detection of thousands of proteins at multiple time points.…

Aspergillus spinal epidural abscess: case presentation and review of the literature.

Study design: In this review, we present a case of Aspergillus spinal epidural abscess (ASEA) and review the literature. Objectives: To provide further insight on a rare condition. Setting: A description of a patient with ASEA in a

Tags: 2018, Issa Husam, Markarian Georges Z, Sangtani Ajleeta, Shweikeh Faris, Shweikeh Mohammed, Spinal cord series and cases, Steinmetz Michael P, Sweiss Fadi, Zyck Stephanie

Incorrect citation.

Tags: 2018, Dannemiller Stanley, Lab animal, Stonerook Michael

Curated compendium of human transcriptional biomarker data.

One important use of genome-wide transcriptional profiles is to identify relationships between transcription levels and patient outcomes. These translational insights can guide the development of biomarkers for clinical application. Data from…

Tags: *Biomarkers, *Transcription, 2018, Bell Avery, Bischoff Anna I, Databases, Disease/genetics, Gene Expression Profiling, Genetic, Golightly Nathan P, Hollingsworth Parker D, Humans, Piccolo Stephen R, Scientific data

How to perform Contrast-Enhanced Ultrasound (CEUS).

"How to perform contrast-enhanced ultrasound (CEUS)" provides general advice on the use of ultrasound contrast agents (UCAs) for clinical decision-making and reviews technical parameters for optimal CEUS performance. CEUS techniques vary between…

Tags: 2018, Averkiou Michalakis, Barr Richard G, Burns Peter N, Calliada Fabrizio, Cancer, Cantisani Vito, Chammas Maria C, Choi Byung, Claudon Michel, Clevert Dirk-Andre, Correas Jean Michel, Cosgrove David, Cui Xin-Wu, D'Onofrio Mirko, Dietrich Christoph F, Dong Yi, Eisenbrey JohnR, Fontanilla Teresa, Franca Meloni Maria, Gilja Odd Helge, guidelines, Ignee Andre, Jang Hyun-Jung, Jenssen Christian, Kim Tae Kyoung, Kono Yuko, Kudo Masatoshi, Lassau Nathalie, Lyshchik Andrej, Moriyasu Fuminori, Nielsen Michael Bachmann, Nolsoe Christian, Piscaglia Fabio, Radzina Maija, Saftoiu Adrian, Schreiber-Dietrich Dagmar, Sidhu Paul S, Sirlin Claude B, Sporea Ioan, Stanczak Maria, Teaching, Ultrasonography, Ultrasound international open, Vezeridis Alexandar, Weskott Hans-Peter, Westerway Sue, Willmann Juergen Karl, Wilson Stephanie R

Informed Consent and the Role of the Treating Physician.

Tags: *Disclosure, *Informed Consent, 2018, Boniface Tom, Consent, Physician-Patient Relations, Research Personnel, Rickert James, The New England journal of medicine, Truth Disclosure

A neurochemical hypothesis for the origin of hominids.

It has always been difficult to account for the evolution of certain human characters such as language, empathy, and altruism via individual reproductive success. However, the striatum, a subcortical region originally thought to be exclusively motor,…

Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits.

Nonalcoholic fatty liver disease (NAFLD) is associated with hepatic mitochondrial dysfunction characterized by reduced ATP synthesis. We applied the (2)H2O-metabolic labeling approach to test the hypothesis that the reduced stability of oxidative…

Browse Items (407 total)