Browse Items · NEOMED Bibliography Database

A histologic review of 27 patients with lichen planopilaris.

BACKGROUND: Lichen planopilaris (LPP) is a potential trichologic emergency that can result in permanent scarring alopecia. Histopathology is a key component of the diagnostic work-up. OBJECTIVE: To identify the key histologic features that…

Tags: 2008, Adult, Aged, Alopecia/etiology/*pathology, Bergfeld Wilma F, Biopsy, Cevasco Nathaniel C, Cicatrix/etiology/*pathology, Female, Humans, Journal of the American Academy of Dermatology, Lichen Planus/complications/diagnosis/*pathology, Male, Middle Aged, Retrospective Studies, Scalp Dermatoses/diagnosis/*pathology, Scalp/*pathology, Somani Najwa, Tandon Yasmeen K

Can aggressive treatment of diabetic foot infections reduce the need for above-ankle amputation?

We retrospectively evaluated the charts of 112 patients with diabetic foot infection to determine if early aggressive surgical intervention improves outcome. All patients were classified into two groups on the basis of the timing of surgical…

The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study).

BACKGROUND: Deficient levels of 25-hydroxyvitamin D [25(OH)D] have been associated with increased fracture risk. Racial differences in fracture risk may be related to differences in bioavailable vitamin D due to single nucleotide polymorphism (SNP)…

Liver disease in the morbidly obese: a review of 1000 consecutive patients undergoing weight loss surgery.

BACKGROUND: Liver disease among the morbidly obese is increasingly prevalent, contributing to significant morbidity. Obesity-related liver pathologies including nonalcoholic steatohepatitis (NASH) have become a leading cause for liver transplant.…

Rectal trauma and associated hemorrhage with the use of the ConvaTec Flexi-Seal fecal management system: report of 3 cases.

The management of fecal incontinence is a struggle to maintain patient hygiene and limit the transmission of nosocomial infections. Intrarectal devices that cause diversion and collection of the fecal stream have been used with increasing frequency.…

Tags: 2010, Aged, Catheterization/*adverse effects/*instrumentation, Chase Daniel, Coughlin Lisa, Diseases of the colon and rectum, Fecal Incontinence/*therapy, Female, Gastrointestinal Hemorrhage/*etiology/surgery, Heaton Bren, Hemostasis, Humans, Male, Metha Jeet, Middle Aged, Pressure Ulcer/*etiology/surgery, Rectum/*injuries/surgery, Sparks Dorothy, Surgical/methods

Lung cancer metastatic to breast: case report and review of the literature.

The incidence of metastases to the breast from nonbreast carcinoma is less than 1% of all breast cancers; of these, adenocarcinoma of the lung to breast is a small proportion (\textless0.1% of breast carcinomas). The imaging findings of a case of…

Sonographic Elastography of Mastitis.

Sonographic elastography has been shown to be a useful imaging modality in characterizing breast lesions as benign or malignant. However, in preliminary research, mastitis has given false-positive findings on both strain and shear wave elastography.…

Focal seizures in a man with multiple medical problems.

Tags: 1992, Abscess/microbiology, Bacteremia/*microbiology, Brain Abscess/*complications/etiology, Hospital practice (Office ed.), Humans, Intestinal Polyps/complications, Listeriosis/*complications/etiology, Male, Middle Aged, Seizures/*etiology, Sliman R J, Soto L F, Splenic Diseases/microbiology

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.

Prox1, an early specific marker for developing liver and pancreas in foregut endoderm has recently been shown to interact with alpha-fetoprotein transcription factor and repress cholesterol 7alpha-hydroxylase (CYP7A1) gene transcription. Using a…

Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques

Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.

The gene encoding cholesterol 7alpha-hydroxylase (CYP7A1) is tightly regulated to control bile acid synthesis and maintain lipid homeostasis. Recent studies in mice suggest that bile acid synthesis is regulated by the fasted-to-fed cycle, and fasting…

Malignancy in horseshoe kidney.

We have reported two cases of adenocarcinoma in a horseshoe kidney and their successful surgical treatment. Review of the literature suggests that transitional cell carcinoma and Wilms' tumor are seen more often than adenocarcinoma in horseshoe…

Tags: 1988, Adenocarcinoma/*diagnostic imaging/surgery, Female, Humans, Kidney Neoplasms/*diagnostic imaging/surgery, Kidney/*abnormalities/surgery, Male, Memo R, Middle Aged, Nephrectomy, Renal Artery/diagnostic imaging, Smith-Behn J, Southern medical journal, Tomography, Urography, X-Ray Computed

Relationship between breast cancer and meningioma.

Several authors have suggested the existence of a relationship between breast cancer and meningioma occurring in the same patient. I describe four patients who had both of these neoplasms and present findings that dispute the implied relationship…

Tags: 1992, Aged, Breast Neoplasms/*diagnosis, Carcinoma, Female, Humans, Intraductal, Meningeal Neoplasms/*diagnosis, Meningioma/*diagnosis, Middle Aged, Neoplasms, Noninfiltrating/*diagnosis, Ovarian Neoplasms/diagnosis, Second Primary/*diagnosis, Smith-Behn J, Southern medical journal, Time Factors

Morgagni hernia: incidental repair during laparoscopic cholecystectomy.

Anterior diaphragmatic hernias are a relatively rare finding. They can occur on either side of the body. We diagnosed and treated a Morgagni hernia during laparoscopic cholecystectomy.

Tags: *Laparoscopy, 1995, Cholecystectomy, Cholelithiasis/*complications/surgery, Diaphragmatic/complications/*surgery, Female, Ghani A, Hernia, Humans, Journal of laparoendoscopic surgery, Laparoscopic, Middle Aged, Smith J

A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice.

OBJECTIVES: Breast cancer-related lymphedema (BCRL) represents a major complication of breast cancer treatment, impacting the quality of life for breast cancer survivors that develop it. The purpose of this review is to evaluate the literature…

Recognition of depression by internal medicine residents.

We studied the ability of internal medicine residents to recognize depressive symptoms in a population of lower socio-economic primary care patients. Four hundred twenty patients completed the short form of the Beck Depression Inventory (BDI).…

Cognitive Behavioral Therapy for Psychosis (CBT-p) Delivered in a Community Mental Health Setting: A Case Comparison of Clients Receiving CBT Informed Strategies by Case Managers Prior to Therapy.

This exploratory case comparison examines the influence of case management activities on engagement and progress in psychotherapy for clients with schizophrenia. Six clients were recruited to participate in ten sessions of Cognitive Behavioral…

Tags: *Case Managers, *CBT-p, *Cognitive behavioral techniques for psychosis, *Cognitive behavioral therapy for psychosis, *Community Mental Health Services, *Continuum of care, *Schizophrenia, 2017, Adult, Case Management, Case-Control Studies, Cognitive Behavioral Therapy/*methods, Cognitive Therapy – Methods, Community mental health journal, Community Mental Health Services, Comparative Studies, Continuity of Patient Care, Department of Psychiatry, Evidence-Based, Exploratory Research, Female, Human, Humans, Knepp Kristen A, Male, Middle Aged, Montesano Vicki L, Munetz Mark R, NEOMED College of Medicine, Outcome Assessment, Professional Practice, Program Implementation – Methods, Psychotic Disorders – Therapy, Psychotic Disorders/*therapy, Schizophrenia, Sivec Harry J, Skubby David, Surveys and Questionnaires

Clinical process examples of cognitive behavioral therapy for psychosis.

Interest in the practice of Cognitive Behavioral Therapy for persistent psychotic symptoms (CBT-p) has increased dramatically in the last decade. Despite the widespread interest, it remains challenging to obtain adequate training in this approach in…

Tags: *Psychotherapeutic Processes, 2013, Adult, Cognitive Behavioral Therapy/*methods, Cognitive Therapy – Methods, Cooperative Behavior, Culture, Defense Mechanisms, Delusions – Psychosocial Factors, Delusions – Therapy, Delusions/psychology/therapy, Female, Hallucinations – Psychosocial Factors, Hallucinations – Therapy, Hallucinations/psychology/therapy, Humans, Internal-External Control, Locus of Control, Male, Middle Age, Middle Aged, Models, Montesano Vicki L, Paranoid Disorders – Psychosocial Factors, Paranoid Disorders – Therapy, Paranoid Disorders/psychology/therapy, Psychological, Psychology, Psychotherapeutic Processes, Psychotherapy (Chicago, Ill.), Psychotic Disorders – Psychosocial Factors, Psychotic Disorders – Therapy, Psychotic Disorders/psychology/*therapy, Schizophrenia – Therapy, Schizophrenia/therapy, Schizophrenic Psychology, Sivec Harry J

Assessing the Accuracy of Eyelid Measurements Utilizing the Volk Eye Check System and Clinical Measurements.

PURPOSE: The purpose of this study was to validate the accuracy of marginal reflex distance 1 (MRD1) measurements obtained by the Volk Eye Check system, a modified smartphone that measures MRD1 automatically, relative to clinical and digital…

Freestanding emergency departments and the trauma patient.

BACKGROUND: Freestanding emergency departments (FEDs) continue to grow in number and more research is needed on these facilities. OBJECTIVE: We sought to characterize the types of injuries and patients who initially presented to two FEDs and were…

Pharmacokinetics of imipenem in serum and skin window fluid in healthy adults after intramuscular or intravenous administration.

The pharmacokinetic profiles of imipenem after intramuscular (i.m.) and intravenous injections were examined in adult volunteers. Levels of imipenem in serum after i.m. injection of a microcrystalline suspension of imipenem-cilastatin (500 mg each)…

An institutional series and contemporary review of bacterial spinal epidural abscess: current status and future directions.

OBJECT: Over the past decade, the incidence of bacterial spinal epidural abscess (SEA) has been increasing. In recent years, studies on this condition have been rampant in the literature. The authors present an 11-year institutional experience with…

Acquired inhibitor to factor VIII in small cell lung cancer: a case report and review of the literature.

Acquired hemophilia (antibodies or inhibitors to factor VIII) is the most common acquired disease affecting clotting factors. It has been described in association with autoimmune disease, malignancy, dermatologic disorders, in the postpartum period,…

Tags: 2001, Ahmed F, Annals of hematology, Carcinoma, Crock R, Department of Internal Medicine, Factor VIII/*antagonists & inhibitors, Humans, Lara L, Lung Neoplasms/*chemistry, Male, Middle Aged, NEOMED College of Medicine, Rutecki G W, Shwaiki A, Small Cell/*chemistry, Whittier F C

Initial experience with laparoscopic surgery: establishing a new surgical procedure.

Laparoscopic surgery impacted the surgical world in the United States in 1990. This report reviews the initial experience of 34 surgeons in 8 teaching hospitals of the Northeastern Ohio Universities College of Medicine. There were 538 cases reported…

Tags: *Education, *Laparoscopy/adverse effects, 1992, Abdu R A, Adult, Can A N, Continuing, Crans C A, Dash S S, General Surgery/*education, Guyton D P, Humans, Internship and Residency, Journal of laparoendoscopic surgery, Kremer R M, Medical, Middle Aged, Sharp W V, Young J S

The medically underserved: who is likely to exercise and why?

Adults who exercise regularly have better health, but only 15% of U.S. adults engage in regular exercise, with some social groups, such as people with lower incomes and women, having even lower rates. This study investigates the rate at which…

Lumbar spine fractures within a complete American cohort: epidemiology and risk factors among military service members.

STUDY DESIGN: Retrospective database review. OBJECTIVE: To describe the incidence of, and risk factors for, lumbar spine fractures within the population of the US military. SUMMARYOF BACKGROUND DATA: Fractures of the lumbar region are an important…

The effect of race on outcomes of surgical or nonsurgical treatment of patients in the Spine Patient Outcomes Research Trial (SPORT).

STUDY DESIGN: Retrospective review of the data collected prospectively through the Spine Patient Outcomes Research Trial (SPORT). OBJECTIVE: To determine the effect that race or ethnicity had on outcomes after spine surgery in the 3 arms of SPORT.…

Outcomes of modular proximal femoral replacement in the treatment of complex proximal femoral fractures: a case series.

BACKGROUND: The treatment of complex femur fractures poses a significant challenge. Even with current advancements and the various implements available for the fixation of femoral fractures, results are often disappointing. This study sought to…

Characterization of the incidence and risk factors for the development of lumbar radiculopathy.

STUDY DESIGN: Epidemiological study of a prospectively collected database. OBJECTIVES: This investigation sought to evaluate the incidence of symptomatic lumbar radiculopathy, and identify risk factors for its development, among individuals serving…

Histochemical analyses of tissue-engineered human menisci.

The field of tissue engineering remains one of the least explored areas of current meniscal research but holds great promise. In this investigation, meniscal fibrochondrocytes were isolated from fresh human meniscal tissue and seeded onto synthetic…

Characterization of combat-related spinal injuries sustained by a US Army Brigade Combat Team during Operation Iraqi Freedom.

BACKGROUND CONTEXT: The United States is presently engaged in the largest scale armed conflict since Vietnam. Despite recent investigations into the scope of injuries sustained by soldiers in Iraq and Afghanistan, little information is available…

Tags: *Iraq War, 2003-2011, 2012, Adolescent, Adult, Belmont Philip J Jr, Female, Goodman Gens P, Humans, Incidence, Male, Middle Aged, Military Personnel/statistics & numerical data, Schoenfeld Andrew J, Spinal Injuries/*epidemiology, The spine journal : official journal of the North American Spine Society, United States/epidemiology, Young Adult

Retrospective review of biopsy results following percutaneous fixation of vertebral compression fractures.

BACKGROUND: Percutaneous vertebral body fixation has been found to provide pain relief and restoration of function for patients with compression fractures. Despite the prevalence of osteoporosis, there are a variety of aetiologies, such as lymphoma,…

Incidence and epidemiology of spinal cord injury within a closed American population: the United States military (2000-2009).

STUDY DESIGN: Cohort study. OBJECTIVES: The objective of this study was to characterize the incidence of spinal cord injury (SCI) within the population of the United States military from 2000-2009. This investigation also sought to define potential…

Skin sterility after application of a vapocoolant spray.

BACKGROUND: Refrigerant sprays have been widely used to reduce pain in the office setting. However, more recently, their use has been limited by both concern regarding flammability and questions of bacterial contamination. OBJECTIVE: We investigated…

Enterovesical fistula presenting as life-threatening normal anion gap metabolic acidosis.

Enterovesical fistula is a rare complication of a variety of inflammatory and neoplastic diseases. It usually presents with pneumaturia, fecaluria, urinary tract infections, or irritable bladder symptoms in the setting of either diverticulitis or…

Tags: 1997, Acidosis/*etiology, American journal of kidney diseases : the official journal of the National Kidney Foundation, Department of Internal Medicine, Diagnosis, Differential, Female, Humans, Hydrogen-Ion Concentration, Intestinal Fistula/*complications/*diagnosis, Middle Aged, NEOMED College of Medicine, Rutecki G W, Saxena R, Urinary Bladder Fistula/*complications/*diagnosis, Whittier F C

Pylephlebitis: a case report and review of outcome in the antibiotic era.

Pylephlebitis or septic thrombophlebitis of the portal vein, a precursor of hepatic abscesses, is an extremely rare and frequently fatal complication of diverticulitis. The following report describes a patient presenting with pylephlebitis and…

Reflex sympathetic dystrophy after modified radical mastectomy: a case report.

Despite the long history of descriptions of reflex sympathetic dystrophy (RSD), much confusion remains regarding its pathogenesis, diagnosis, and treatment. It most commonly occurs after trauma and is more frequent in women, white persons, and the…

Tags: *Mastectomy, *Postoperative Complications, 1993, Arm/physiopathology, Electromyography, Female, Humans, Middle Aged, Movement, Pain, Radical, Reflex Sympathetic Dystrophy/*etiology/physiopathology/therapy, Saddison D K, Surgery, Vanek V W

Measuring residual activity of topical antimicrobials: is the residual activity of chlorhexidine an artefact of laboratory methods?

Residual activity of chlorhexidine gluconate (CHG) was evaluated by pretreating hands with CHG and then touching Staphylococcus aureus dried on to stainless steel discs. By this method, no reduction in bacteria was observed up to 15 min, suggesting…

Nephrologists' subjective attitudes towards end-of-life issues and the conduct of terminal care.

Decisions which determine the duration and outcome of terminal care should be influenced by patient autonomy. Studies suggest, however, that end-of-life decision-making is more complex than a single principle and that physicians may be responsible…

[Clues to recognition of kidney disease in archaeologic record: characteristics and occurrence of leontiasis ossium].

The possible osseous effect of kidney dysfunction was evaluated in a modern skeletal population for future use in assessment of archaeologic samples. Frequency and distribution on the bones of cysts, articular surface alterations, subperiosteal…

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