Browse Items · NEOMED Bibliography Database

Daily exercise and gender influence postexercise cardiac autonomic responses in hypertensive rats.

The influence of daily spontaneous running (DSR) and gender on postexercise cardiac autonomic responses was examined in spontaneously hypertensive rats. Rats were weaned at 4-5 wk of age and were randomly assigned to a sedentary (7 males and 6…

Identification of a bile acid response element in the cholesterol 7 alpha-hydroxylase gene CYP7A.

The transcriptional activity of the cholesterol 7 alpha-hydroxylase gene CYP7A is repressed by bile acids. Taurine conjugates of chenodeoxycholate and deoxycholate, but not cholate and ursodeoxycholate, inhibited the CYP7A promoter/luciferase…

Laboratory exercise using "virtual rats" to teach endocrine physiology.

Animal experimentation is limited in many curricula due to the expense, lack of adequate animal facilities and equipment, and limited experience of the teachers. There are also ethical concerns dealing with the comfort and safety of the animals. To…

Relating basic concepts of pulmonary mechanics to clinical situations.

Tags: *Education, 1997, Biomechanical Phenomena, Curriculum, Graduate, Humans, Lung Compliance/physiology, Lung Diseases/physiopathology, Maron M B, Medical, Physiology/*education, Pneumothorax/physiopathology, Respiratory Mechanics/*physiology, The American journal of physiology, Thorax/physiology, Vital Capacity

Student identification of ethical issues in a primary care setting.

Ethical issues in the clinical arena have received significant attention during the past few decades. Limited focus has been directed toward ethical issues in the primary care office setting. A study was conducted to determine the ethical…

Two faces of "rheumatoid arthritis": type a versus type B disease.

Is rheumatoid arthritis one disease or a "catch-all" term for inflammatory arthritis that tends to spare axial joints? We have subdivided "rheumatoid arthritis," utilizing the criteria of periarticular osteopenia and marginally (distributed),…

Tags: 1997, Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, Rothschild B M

Incidence, etiologic pathogens, and diagnostic testing of community-acquired pneumonia.

Determination of the etiologic pathogens of community-acquired pneumonia has been problematic because of the lack of reliable rapid laboratory diagnostic tools as well as the controversy concerning diagnostic criteria. In the studies reviewed here, a…

Tags: 1997, AIDS-Related Opportunistic Infections/diagnosis/microbiology, Community-Acquired Infections/diagnosis/epidemiology/microbiology, Current opinion in pulmonary medicine, Department of Internal Medicine, File T M Jr, Humans, NEOMED College of Medicine, Pneumonia/diagnosis/epidemiology/*microbiology, Tan J S

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia.

Five hundred ninety patients were enrolled in a prospective, multicenter, randomized trial comparing the efficacy and safety of 7 to 14 days of levofloxacin treatment with that of ceftriaxone and/or cefuroxime axetil in the management of…

Testicular capillary hemangioma: an unusual diagnosis suggested by duplex color flow ultrasound findings.

Tags: *Ultrasonography, 1997, Adolescent, Capillary/*diagnostic imaging, Color, Doppler, Hemangioma, Humans, Male, McMahon D R, Nasrallah P F, Stille J R, Testicular Neoplasms/*diagnostic imaging, The Journal of urology

Golfer's rib stress fracture (Duffer's fracture). Scintigraphic appearance.

Tags: 1997, Clinical nuclear medicine, Fractures, Goyal M, Hanelin L G, Humans, Kenney A J 3rd, Male, Middle Aged, Radionuclide Imaging, Rib Fractures/*diagnostic imaging, Stress/*diagnostic imaging

Medullary cavity stenosis of the metacarpals. Scintigraphic appearance.

Tags: 1997, Adult, Arshanskiy Y S, Clinical nuclear medicine, Female, Hanelin L G, Humans, Kenney A J 3rd, Metacarpus/*abnormalities/*diagnostic imaging, Radionuclide Imaging

Professional development of medical students: problems and promises.

Observers and critics of the medical profession, both within and without, urge that more attention be paid to the moral sensibilities, the characters, of medical students. Passing on particular moral values and actions to physicians has always been…

Tags: *Character, *Education, *Professional Practice, 1997, Academic medicine : journal of the Association of American Medical Colleges, Cultural Diversity, Department of Family & Community Medicine, Feminism, Humans, Knowledge, Medical, Medical/*psychology, Models, NEOMED College of Medicine, Students, Theoretical, United States, Wear D

Vaginovesicostomy using absorbable staples.

Tags: *Surgical Stapling, 1997, British journal of urology, Chronic/complications, Cystostomy/instrumentation/*methods, Female, Green D H, Humans, Khoudary K P, Khoudary M L, Kidney Failure, Recurrence, Summers J L, Suppuration/etiology, Urinary Bladder Diseases/*surgery, Urinary Diversion/adverse effects, Vagina/*surgery, Wilkerson J E

The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.

The effects of phenobarbital, phenytoin, and valproic acid on pharmacologically isolated NMDA-EPSP, AMPA-EPSP, and GABA-IPSPs were examined in rat hippocampal slices. Phenobarbital (0.05 mg/ml) had no effect on the NMDA-EPSP, but decreased the slope…

Tags: 1997, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/*pharmacology, Animals, Anticonvulsants/*pharmacology, Brain research bulletin, Brown-Croyts L M, Electrophysiology, gamma-Aminobutyric Acid/*pharmacology, Hippocampus/*drug effects/physiology, Inbred Strains, Ko G Y, Male, N-Methylaspartate/*pharmacology, Phenobarbital/pharmacology, Phenytoin/pharmacology, Rats, Teyler T J, Valproic Acid/pharmacology

The effects of aging on spinal neurochemistry in the rat.

The purpose of this study was to investigate how the aging process alters the basal levels of serotonin, norepinephrine, dopamine, and their respective metabolites in the spinal cord using high-performance liquid chromatography and electrochemical…

Tags: 1997, Aging/*metabolism, Animals, Brain research bulletin, Chromatography, Crisp T, Dopamine/metabolism, Electrochemistry/methods, Gordon T L, High Pressure Liquid, Inbred F344, King M A, Ko M L, Male, Norepinephrine/metabolism, Rats, Serotonin/metabolism, Spinal Cord/*metabolism

Estrogen differentially modulates nicotine-evoked dopamine release from the striatum of male and female rats.

In the present experiment we examined the effects of an in vitro infusion of nicotine (10 microM) upon dopamine release from superfused striatum of castrated male and female rats treated or not treated with estrogen. Estrogen exerted bidirectional…

Tags: 1997, Anderson L I, Animals, Corpus Striatum/drug effects/*metabolism, Dluzen D E, Dopamine/*metabolism, Estradiol/*pharmacology, Female, In Vitro Techniques, Kinetics, Male, Neuroscience letters, Nicotine/*pharmacology, Orchiectomy, Ovariectomy, Rats, Sex Characteristics, Sprague-Dawley

Enterovesical fistula presenting as life-threatening normal anion gap metabolic acidosis.

Enterovesical fistula is a rare complication of a variety of inflammatory and neoplastic diseases. It usually presents with pneumaturia, fecaluria, urinary tract infections, or irritable bladder symptoms in the setting of either diverticulitis or…

Tags: 1997, Acidosis/*etiology, American journal of kidney diseases : the official journal of the National Kidney Foundation, Department of Internal Medicine, Diagnosis, Differential, Female, Humans, Hydrogen-Ion Concentration, Intestinal Fistula/*complications/*diagnosis, Middle Aged, NEOMED College of Medicine, Rutecki G W, Saxena R, Urinary Bladder Fistula/*complications/*diagnosis, Whittier F C

Oral contraceptive failure rates and oral antibiotics.

BACKGROUND: Despite anecdotal evidence of a possibility of decreased effectiveness of oral contraceptives (OCs) with some antibiotics, it is not known whether antibiotic use in dermatologic practices engenders any increased risk of accidental…

Lesions of the basolateral amygdala abolish the ability of drug associated cues to reinstate responding during withdrawal from self-administered cocaine.

This study investigated the ability of bilateral excitotoxic lesions of the basolateral amygdala (BLA) to disrupt cocaine self-administration, responding during extinction sessions, and stimulus cued recovery of extinguished responding in rats. BLA…

Discriminative characteristics of high and low cocaine administration: effect of other psychostimulants.

Two groups of N/Nih male rats were trained to discriminate saline vehicle from either 2.0 mg/kg (n = 10) or 10.0 mg/kg (n = 10) cocaine in a food-motivated, two-lever operant paradigm. The rats trained at the low-dose cocaine took a significantly…

Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.

Ten male N/Nih rats were trained to discriminate between the interoceptive cues produced by the purportedly dopaminergically-mediated drug d-amphetamine at 0.4 mg/kg intraperitoneally administered 20 min prior to training and those produced by the…

Daily exercise reduces fat, protein and body mass in male but not female rats.

This study was designed to compare the estimated energy balance, linear growth (body and bone lengths) and body composition (all components including body mass, total body water, fat, protein and ash) response to daily spontaneous running (DSR) in…

Uterine problems discovered after presumed hysterectomy: the Manchester operation revisited.

BACKGROUND: The Manchester operation consists of amputation of the cervix, leading some patients to believe that they have undergone a hysterectomy. CASES: A 69-year-old woman with vaginal discharge proved to have a well-differentiated adenocarcinoma…

Tags: *Hysterectomy, 1997, 80 and over, Aged, Amputation/*methods, Cervix Uteri/*surgery, DeLancey J O, Devine J B, Diagnosis, Differential, Female, Hopkins M P, Humans, Obstetrics and gynecology, Uterine Diseases/*diagnosis/surgery, Uterine Prolapse/*surgery

Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.

Fenfluramine, a drug that induces increased synaptic serotonin, was used to train Fawn-Hooded rats in a drug discrimination paradigm. This strain of rats is thought to possess a genetic serotonin storage abnormality. The intent of the study was to…

Discrete versus cumulative dosing in dose-response discrimination studies.

This study describes the results of a 'side-by-side' comparison of two measurement techniques and two dosing regimens in a discrimination study using rats trained to either 10 mg/kg cocaine or 2 mg/kg 3,4-methylenedioxymethamphetamine (MDMA). The…

Tags: 1997, 4-methylenedioxyamphetamine/*pharmacology, Animals, Chemical, Cocaine/*pharmacology, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Drug Administration Schedule, Drug Evaluation, European journal of pharmacology, Male, N-Methyl-3, Preclinical, Rats, Schechter M D, Sprague-Dawley, Stimulation

Olanzapine attenuates the reinforcing effects of cocaine.

The possibility that the atypical neuroleptic olanzapine can antagonize the ability of cocaine to produce both conditioned place preference and self-administration in rats was investigated. Pre-treatment with olanzapine (3.0, 4.5 mg/kg, but not 1.5…

Discrimination of cocaethylene in rats trained to discriminate between its components.

Two groups of eight male Normalized/National Institutes of Health (N/Nih) rats were used in a food-motivated, 2-lever drug discrimination task with one group being trained to discriminate between 10 mg/kg cocaine vs. 1 g/kg ethanol, whereas the…

Tags: 1997, Animals, Cocaine/*analogs & derivatives/*pharmacology, Discrimination Learning/*drug effects, Dose-Response Relationship, Drug, Ethanol/*pharmacology, European journal of pharmacology, Male, Rats, Schechter M D

Estrogen as a neuromodulator of MPTP-induced neurotoxicity: effects upon striatal dopamine release.

The effects of estrogen upon MPTP-induced neurotoxicity were examined using in vitro superfusion. In Experiment 1, striatal tissue from ovariectomized rats was infused with MPP+ (10 microM), a combination of MPP+ and 17beta-estradiol (300 nM), the…

Tags: *MPTP Poisoning, 1-Methyl-4-phenylpyridinium/toxicity, 1997, Animals, Brain research, Disshon K A, Dluzen D E, Dopamine Agents/*toxicity, Dopamine/*metabolism, Estradiol/pharmacology, Estrogens/*physiology, Female, Neostriatum/drug effects/*metabolism, Neurotransmitter Agents/*physiology, Ovariectomy, Rats, Sprague-Dawley

The effect of intermittent-release intraperitoneal chemotherapy on wound healing.

OBJECTIVE: Our purpose was to study the effect on wound healing when intraperitoneal chemotherapy was instilled on a daily basis. STUDY DESIGN: Intraperitoneal carboplatin, Taxol, or saline solution was instilled daily into 70 rats after they…

Tags: 1997, American journal of obstetrics and gynecology, Animals, Antineoplastic Agents/administration & dosage/*pharmacology, Carboplatin/administration & dosage/*pharmacology, Holda S, Hopkins M P, Infusions, Laparotomy, Male, Paclitaxel/administration & dosage/*pharmacology, Parenteral, Rats, Sprague-Dawley, Tissue Adhesions/chemically induced, von Gruenigen V E, Weber B, Wound Healing/*drug effects

Splenic rupture from colonoscopy. A report of two cases and review of the literature.

Splenic injury after colonoscopy is rare. Only 15 cases previously have been reported in the English literature. Partial capsular avulsion is the proposed mechanism of injury. Any condition causing increased splenocolic adhesions may be a…

Tags: 1997, Colonoscopy/*adverse effects, Espinal E A, Female, Follow-Up Studies, Hoak T, Humans, Middle Aged, Porter J A, Slezak F A, Spleen/injuries, Splenectomy, Splenic Rupture/*etiology/surgery, Surgical endoscopy, Tomography, X-Ray Computed

New Kohatius (Omomyidae) from the Eocene of Pakistan.

Tags: *Primates, 1997, Animals, Arif M, Department of Anatomy & Neurobiology, Hussain S T, Journal of human evolution, NEOMED College of Medicine, Pakistan, Thewissen J G, Tooth/*ultrastructure

Pure embryonal rhabdomyosarcoma of the fallopian tube.

Rhabdomyosarcoma is a neoplasm of childhood which commonly arises in the genitourinary tract. Reported locations include the bladder, prostate, paratestis, vagina, uterus, cervix, and ovary. Rhabdomyosarcomas have been reported to occur in the…

Tags: 1997, Adolescent, Buchwalter C L, Department of Radiology, Embryonal/*pathology, Fallopian Tube Neoplasms/*pathology, Female, Fromm M, Gynecologic oncology, Hart W R, Humans, Jenison E L, Mehta V T, NEOMED College of Medicine, Obstetrics and gynecology, Rhabdomyosarcoma

The isolation and characterization of the soluble and membrane-bound porcine cytochrome b5 cDNAs.

In some male pigs, there is an increased production of the testicular 16 androstene steroids which end up being concentrated in fatty tissue. When the meat is cooked, a disagreeable odor/flavor is produced, a phenomenon known as "boar taint." All…

Tags: 1997, Amino Acid Sequence, Animals, Base Sequence, Biochemical and biophysical research communications, Blotting, Complementary/blood/*chemistry/*isolation & purification, Cytochromes b5/blood/*chemistry/genetics/*isolation & purification, DNA, Male, Membrane Proteins/*chemistry/genetics/*isolation & purification, Molecular Sequence Data, Solubility, Southern, Steggles A W, Swine, Testis/enzymology, VanDerMark P K

What happens when effective outpatient civil commitment is terminated?

Outpatient civil commitment can be effective in slowing the revolving door for selected patients, but it may not be the best mechanism for ensuring treatment over time.

Involuntary treatment of substance abuse disorders.

The authors argue for the extension of mandatory treatment to persons gravely disabled by substance abuse. The problem is examined from ideological, clinical, legal, economic, and ethical perspectives.

Tags: *Commitment of Mentally Ill/legislation & jurisprudence, 1997, Adult, Cost of Illness, Diagnosis, Dual (Psychiatry), Ethics, Galon P A, Human Rights, Humans, Liebelt R A, Male, Medical, New directions for mental health services, Substance-Related Disorders/economics/*rehabilitation, United States

Browse Items (165 total)