Browse Items · NEOMED Bibliography Database

Phase I/II prospective trial of autologous platelet tissue graft in gynecologic surgery.

STUDY OBJECTIVE: To perform the original phase I/II trial of autologous platelet tissue graft in gynecologic surgery to evaluate toxicity and efficacy on decreasing pain. DESIGN: Prospective nonrandomized trial (Canadian Task Force classification…

Coccidioides parenchymal cerebral abscess in the setting of lymphoma.

Coccidioides immitis is a dimorphic fungus endemic to southwestern United States of America. When symptomatic, infection usually results in a subacute respiratory infection. Disseminated coccidioidomycosis occurs in less than 1% of all cases. We…

Tags: 2015, Aged, Brain Abscess/*etiology/pathology, Coccidioides, Coccidioides/*pathogenicity, Coccidioidomycosis/*complications, Follicular lymphoma, Follicular/*drug therapy, Fungus, Grabowski Matthew, Humans, Immunologic Factors/*therapeutic use, Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, Lymphoma, Male, Motley Benjamin D, Prayson Richard A, Rituximab/*therapeutic use, United States

Reversal of antiplatelet therapy in traumatic intracranial hemorrhage: Does timing matter?

Reversal of antiplatelet therapy with platelet transfusion in traumatic intracranial hemorrhage remains controversial. Several studies have examined this topic but few have investigated whether the timing of transfusion affects outcomes. Patients…

Development of Entrustable Professional Activities for Hospice and Palliative Medicine Fellowship Training in the United States.

CONTEXT: Entrustable Professional Activities (EPAs) represent the key physician tasks of a specialty. Once a trainee demonstrates competence in an activity, they can then be "entrusted" to practice without supervision. A physician workgroup of the…

Total thyroidectomy: is morbidity higher for Graves' disease than nontoxic goiter?

BACKGROUND: Total thyroidectomy for treatment of Graves' disease is controversial and much of the debate centers on the concern for complications. The purpose of this study was to evaluate the morbidity of total thyroidectomy for Graves' disease and…

Tags: 2011, Adult, Aged, Female, Goiter, Graves Disease/pathology/*surgery, Humans, Hypocalcemia/epidemiology, Male, McHenry Christopher R, Middle Aged, Morbidity, Nodular/pathology/*surgery, Postoperative Complications/epidemiology, Retrospective Studies, The Journal of surgical research, Thyroidectomy/*adverse effects, Welch Kellen C

Selective lateral compartment neck dissection for thyroid cancer.

BACKGROUND: Compartment-oriented lymph node dissection in patients with thyroid cancer and macroscopic lymph node metastases reduces recurrence and improves survival. However, the extent of lymph node dissection remains controversial. The purpose of…

Safe Readministration of Intravenous Thrombolysis in Recurrent Basilar Thrombosis.

We report a patient who had recurrence of stroke in the basilar artery territory because of repeat thrombosis, and was administered intravenous recombinant tissue plasminogen activator (IV-rtPA) twice within a span of 3 weeks without any adverse…

Tags: 2018, Aged, Basilar Artery, Basilar Artery – Drug Effects, Basilar Artery – Physiopathology, Basilar Artery/diagnostic imaging/*drug effects/physiopathology, Cerebral Angiography – Methods, Cerebral Angiography/methods, Computed Tomography Angiography, Department of Internal Medicine, Drug Administration Schedule, Fibrinolytic Agents – Administration and Dosage, Fibrinolytic Agents – Adverse Effects, Fibrinolytic Agents/*administration & dosage/adverse effects, Humans, Infusions, Intracranial Thrombosis, Intracranial Thrombosis – Drug Therapy, Intracranial Thrombosis – Physiopathology, Intracranial Thrombosis/diagnostic imaging/*drug therapy/physiopathology, Intravenous, Itrat Ahmed, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Khan Alina, Magnetic Resonance Imaging, Male, medication safety, NEOMED College of Medicine, Recombinant Proteins – Administration and Dosage, Recombinant Proteins/administration & dosage, Recurrence, recurrent stroke, Repeat Procedures, Retreatment, thrombolysis, Thrombolytic Therapy – Adverse Effects, Thrombolytic Therapy – Methods, Thrombolytic Therapy/adverse effects/*methods, Thrombosis, Time Factors, Tissue Plasminogen Activator – Administration and Dosage, Tissue Plasminogen Activator – Adverse Effects, Tissue Plasminogen Activator/*administration & dosage/adverse effects, Treatment Outcome, Treatment Outcomes

Effectiveness of an extracellular matrix graft (OASIS Wound Matrix) in the treatment of chronic leg ulcers: a randomized clinical trial.

BACKGROUND: Venous leg ulcers are a major cause of morbidity, economic loss, and decreased quality of life in affected patients. Recently, biomaterials derived from natural tissue sources have been used to stimulate wound closure. One such…

Intrajoint comparisons of gene expression patterns in human osteoarthritis suggest a change in chondrocyte phenotype.

Osteoarthritis (OA) is a degenerative cartilage disease with varying degrees of severity within a given joint. The purpose of this study was to define a sampling procedure for comparing human minimal and advanced OA cartilage in the same patient and…

Predictive model for survival in patients having repeat radiation treatment for painful bone metastases.

PURPOSE: To establish a survival prediction model in the setting of a randomized trial of re-irradiation for painful bone metastases. METHODS: Data were randomly divided into training and testing sets with an approximately 3:2 ratio. Baseline factors…

Gender and age make no difference in the re-irradiation of painful bone metastases: A secondary analysis of the NCIC CTG SC.20 randomized trial.

BACKGROUND AND PURPOSE: Patient's gender and age may influence physicians in prescribing palliative radiotherapy. The purpose of this secondary analysis of the National Cancer Institute of Canada Clinical Trials Group Symptom Control Trial SC.20 was…

Tags: *Age, *Bone metastases, *Gender, *Pain response, *Quality of Life, *Radiotherapy, *Re-irradiation, 2018, Age Factors, Aged, Babington Scott, Bone Neoplasms/physiopathology/*radiotherapy/*secondary, Brundage Michael, Cancer Pain/etiology/*radiotherapy, Chow Edward, Chow Ronald, Demas William F, Ding Keyue, Female, Ganesh Vithusha, Hartsell William F, Hoskin Peter, Humans, Male, Meyer Ralph M, Middle Aged, Nabid Abdenour, Pain Measurement, Palliative Care/methods/statistics & numerical data, Patient Reported Outcome Measures, Physicians'/*statistics & numerical data, Practice Patterns, Quality of Life, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Re-irradiation, Roos Daniel, Sex Factors, van Acht Manouk, van der Linden Yvette M, Wanders Rinus, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y, Zhu Liting

The utility of hair cortisol concentrations in the prediction of PTSD symptoms following traumatic physical injury.

RATIONALE: Although cortisol alterations have been associated with posttraumatic stress disorder (PTSD) and PTSD symptoms (PTSS), the direction of association is mixed. Cortisol which is measured in blood, saliva, or urine is subject to transient…

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

Can ultrasound be used to predict malignancy in patients with a thyroid nodule and an indeterminate fine-needle aspiration biopsy?

PURPOSE: The purpose of this study was to evaluate whether ultrasonography is helpful in predicting malignancy in patients with a thyroid nodule and atypia/follicular lesion of undetermined significance (AFLUS). METHODS: All patients with a…

Feasibility of a lifestyle intervention for overweight/obese endometrial and breast cancer survivors using an interactive mobile application.

OBJECTIVE: The study aimed to assess a one-month lifestyle intervention delivered via a web- and mobile-based weight-loss application (app) (LoseIt!) using a healthcare-provider interface. METHODS: Early-stage overweight/obese (body mass index…

Chemotherapy completion in elderly women with ovarian, primary peritoneal or fallopian tube cancer - An NRG oncology/Gynecologic Oncology Group study.

PURPOSE: A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline Instrumental Activities of Daily Living (IADL) score with ability to complete 4 cycles of first line…

Quality of life, symptoms and care needs in patients with persistent or recurrent platinum-resistant ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.

OBJECTIVES: The goals of treating recurrent platinum-resistant ovarian cancer are palliative, aimed at reducing symptoms and improving progression free survival. A prospective trial was conducted to determine the prevalence and severity of symptoms,…

Awake aortic aneurysm repair in patients with severe pulmonary disease.

BACKGROUND: We report the use of retroperitoneal aortic aneurysm repair utilizing exclusive regional anesthesia (no intubation or inhalation anesthetic) in high pulmonary risk patients. METHODS: Six patients were retrospectively reviewed. Pulmonary…

Tags: *Consciousness, 1999, Abdominal/*surgery, Administration, Aged, Albuterol/administration & dosage/therapeutic use, American journal of surgery, Anesthesia, Aortic Aneurysm, Blood Loss, Bronchodilator Agents/administration & dosage/therapeutic use, Critical Care, Epidural, Forced Expiratory Volume/physiology, General, Hirko M K, Home Care Services, Hospitalization, Humans, Hypnotics and Sedatives/administration & dosage, Iliac Aneurysm/*surgery, Inhalation, Intravenous, Koler A J, Labat G C, Length of Stay, Lung Diseases/*complications/drug therapy/therapy, McGregor W E, Oxygen Inhalation Therapy, Perni V, Retroperitoneal Space, Retrospective Studies, Risk Factors, Rubin J R, Safety, Steroids/administration & dosage/therapeutic use, Surgical, Theophylline/administration & dosage/therapeutic use, Time Factors, Vital Capacity/physiology

Uterine problems discovered after presumed hysterectomy: the Manchester operation revisited.

BACKGROUND: The Manchester operation consists of amputation of the cervix, leading some patients to believe that they have undergone a hysterectomy. CASES: A 69-year-old woman with vaginal discharge proved to have a well-differentiated adenocarcinoma…

Tags: *Hysterectomy, 1997, 80 and over, Aged, Amputation/*methods, Cervix Uteri/*surgery, DeLancey J O, Devine J B, Diagnosis, Differential, Female, Hopkins M P, Humans, Obstetrics and gynecology, Uterine Diseases/*diagnosis/surgery, Uterine Prolapse/*surgery

Dactylitis: implications for clinical practice.

OBJECTIVES: To assess the specificity of dactylitis for the diagnosis of spondyloarthropathy, sarcoidosis, and gout; and to characterize dactylitis specifically associated with gout. METHODS: Dactylitis was prospectively assessed among all…

Reversible ectropion after long-term use of topical tretinoin on photodamaged skin.

Tags: 1992, Administration, Aged, Asselin D, Brodell L P, Brodell R T, Cutaneous, Ectropion/*chemically induced, Face, Female, Humans, Journal of the American Academy of Dermatology, Middle Aged, Skin Aging/*drug effects, Tretinoin/administration & dosage/*adverse effects

Difficulty in predicting bacteremia in elderly emergency patients.

STUDY OBJECTIVES: To characterize the clinical presentation and identify factors predictive of bacteremia in elderly patients. DESIGN: Retrospective review of emergency department charts, hospital records, and microbiology reports. SETTING: Community…

Using paramedics to identify at-risk elderly.

OBJECTIVES: To evaluate paramedics' ability to identify elderly at risk and refer them for assessment and service. DESIGN: A prospective nonrandomized open trial. SETTING: Akron, Ohio, a midsize city with a well-developed advanced life support…

Tags: *Emergency Medical Technicians, *Geriatric Assessment, 1992, Aged, Annals of emergency medicine, Department of Emergency Medicine, Female, Gerson L W, Humans, Male, NEOMED College of Medicine, Ohio, Predictive Value of Tests, Prospective Studies, Records, Risk Factors, Schelble D T, Wilson J E

Case finding for cognitive impairment in elderly emergency department patients.

STUDY OBJECTIVES: To determine the feasibility of a case-finding program for cognitive impairment in elderly emergency department patients, and to describe the prevalence of cognitive impairment in screened patients and identify factors associated…

Reversible acute renal failure as an atypical presentation of ischemic nephropathy.

Ischemic nephropathy (IN) is defined as a clinically significant reduction in glomerular filtration rate in patients with hemodynamically significant obstruction to renal artery flow in a solitary functioning kidney or with bilateral renal artery…

Tags: 1993, Acute Kidney Injury/complications/*etiology, Aged, American journal of kidney diseases : the official journal of the National Kidney Foundation, Anuria/etiology, Cox J, Department of Internal Medicine, Diagnosis, Differential, Female, Humans, Male, Middle Aged, NEOMED College of Medicine, Renal Artery Obstruction/complications/*diagnosis, Roche Z, Rutecki G, Whittier F C

Degenerative sternoclavicular arthritis and hyperostosis.

Symptomatic arthritic involvement of the sternoclavicular joint is relatively uncommon and can be a result of distant trauma, infection, and sternocostoclavicular hyperostosis, post-menopausal arthritis, condensing osteitis of the proximal clavicle,…

Evaluation of the patient with seizures: an evidence based approach.

Statistics tell us that as many as 1 in 20 members of the population will suffer a seizure at some point in their lifetime, a figure which becomes even more likely if one lives to the age of 80. Thus, a careful evidence based approach to the patient…

Can tamoxifen cause a significant mammographic density change in breast parenchyma?

To evaluate tamoxifen-induced glandular tissue density changes in women who are on an adjuvant tamoxifen therapy. We examined serial mammograms of 27 women (average age 67) who had surgery for unilateral breast carcinoma and were on tamoxifen for 5…

Tags: 2001, Aged, Antineoplastic Agents, Breast Neoplasms/*diagnostic imaging/*prevention & control/surgery, Breast/anatomy & histology/*drug effects, Clinical imaging, Computer-Assisted, Female, Goyal M, Hormonal/*pharmacology, Humans, Image Processing, Konez O, Mammography, Reaven R E, Tamoxifen/*pharmacology

Outcome of treatment of respiratory tract infections due to Streptococcus pneumoniae, including drug-resistant strains, with pharmacokinetically enhanced amoxycillin/clavulanate.

The efficacy of a new pharmacokinetically enhanced formulation of amoxycillin/clavulanate (AMX/CA) 2000/125 mg, twice daily, designed to provide adequate levels of amoxycillin over the 12-h dosing interval to eradicate penicillin-resistant…

Tags: *Treatment Outcome, 2002, 80 and over, Adolescent, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination/administration & dosage/*pharmacokinetics/pharmacology/*therapeutic use, Amoxicillin/adverse effects/therapeutic use, Bacterial, Bacterial/drug therapy/immunology, Bronchitis/drug therapy/microbiology, Combination/adverse effects/*therapeutic use, Department of Internal Medicine, Double-Blind Method, Drug Administration Schedule, Drug Resistance, Drug Therapy, Female, File Thomas M Jr, Follow-Up Studies, Humans, International journal of antimicrobial agents, Jacobs Michael R, Male, Microbial Sensitivity Tests, Middle Aged, Multicenter Studies as Topic, NEOMED College of Medicine, Pneumonia, Poole Michael D, Respiratory Tract Infections/*drug therapy/metabolism/microbiology, Streptococcal Infections/*drug therapy/metabolism/microbiology, Streptococcus pneumoniae/*drug effects, Wynne Brian

Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial.

BACKGROUND: Although repeat radiation treatment has been shown to palliate pain in patients with bone metastases from multiple primary origin sites, data for the best possible dose fractionation schedules are lacking. We aimed to assess two dose…

Tags: *Dose Fractionation, *Radiotherapy, 2014, Aged, Analgesics – Therapeutic Use, Analgesics/therapeutic use, Australia, Babington Scott, Bone Neoplasms, Bone Neoplasms – Complications, Bone Neoplasms – Radiotherapy, Bone Neoplasms/complications/*radiotherapy/*secondary, Brief pain inventory, Brundage Michael D, Canada, Cauda Equina, Chen Bingshu E, Chi Square Test, Chi-Square Distribution, Chow Edward, Clinical Assessment Tools, Clinical Trials, Computer-Assisted, Computer-Assisted – Adverse Effects, Computer-Assisted/adverse effects, Demas William F, Europe, Female, Fractures, Funding Source, Hartsell William F, Hoskin Peter, Human, Humans, Intention to Treat Analysis, Israel, Logistic Models, Logistic Regression, Male, Meyer Ralph M, Middle Age, Middle Aged, Nabid Abdenour, New Zealand, Odds Ratio, Oei Bing, Pain – Diagnosis, Pain – Drug Therapy, Pain – Etiology, Pain – Radiotherapy, Pain Measurement, Pain/diagnosis/drug therapy/*etiology/*radiotherapy, Questionnaires, Radiation, Radiation Dosage, Radiotherapy, Radiotherapy Planning, Risk Factors, Roos Daniel, Scales, Spinal Cord Compression – Etiology, Spinal Cord Compression/etiology, Spontaneous – Etiology, Spontaneous/etiology, Surveys and Questionnaires, The Lancet. Oncology, Time Factors, Tissing-Tan Caroline J A, Treatment Outcome, Treatment Outcomes, van der Linden Yvette M, Wilson Carolyn F, Wong Rebecca K S, Wu Jackson S Y

Epidemiology and clinical outcomes of patients with Fusobacterium bacteraemia.

This 10-year retrospective study assessed the epidemiology and outcomes of patients with Fusobacterium bacteraemia (FB) at a tertiary-care hospital in the

Tags: *Hospital Mortality, 2013, 80 and over, Adult, Aged, Bacteremia – Mortality, Bacteremia – Physiopathology, Bacteremia/*mortality/physiopathology, Bonilla H F, Creatinine – Blood, Creatinine/blood, Epidemiology and infection, Female, Fusobacterium Infections – Mortality, Fusobacterium Infections – Physiopathology, Fusobacterium Infections/*mortality/physiopathology, Goldberg E A, Hewit M, Hospital Mortality, Hospitals, Human, Humans, Intensive Care Units – Statistics and Numerical Data, Intensive Care Units/statistics & numerical data, Length of Stay – Statistics and Numerical Data, Length of Stay/statistics & numerical data, Male, Middle Age, Middle Aged, Retrospective Design, Retrospective Studies, Risk Factors, Special – Statistics and Numerical Data, Tertiary Care Centers/*statistics & numerical data, Treatment Outcome, Treatment Outcomes, United States, United States/epidemiology, Venkat-Ramani T

Geriatric Disaster Preparedness.

INTRODUCTION: The elderly population has proven to be vulnerable in times of a disaster. Many have chronic medical problems for which they depend on medications or medical equipment. Some older adults are dependent on caregivers for managing their…

The assessment and treatment of back and neck pain: an initial investigation in a primary care practice-based research network.

AIM: The purpose of this study was to conduct an exploratory examination of the current state of non-malignant acute and chronic back and neck pain assessment and management among primary care providers in a multi-site, practice-based research…

Direct care staff and parents'/legal guardians' perspectives on end-of-life care in a long-term care facility for medically fragile and intellectually disabled pediatric and young adult residents.

OBJECTIVE: Children and young adults with severe disabilities and their families are faced with enormous challenges throughout the lifespan, including admitting the child to a long-term care facility (LTCF) and making end-of-life (EOL) care…

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