Browse Items · NEOMED Bibliography Database

The Zoster Vaccine Rapidly Loses Effectiveness in Adults Over 60.

The article reports that the Herpes Zoster (HZ) vaccine has decreased its effectiveness in adults that are above 60 years of age. Topics discussed include decline in beneficial effect of the HZ vaccine; determination of an optimal re-dosing strategy…

Cranberry Capsules Are Not Effective in Preventing Bacteriuria with Pyuria in Elderly Women in Nursing Homes...Ju th a n i-M e h ta M , Van N ess PH, B ianco L, e t al. Effect o f c ra n b e rry capsules o n b a cteriu ria plus pyu ria a m o n g o ld e r w o m e n in nursing h o m e s: A ra n d o m iz e d clinical trial. JAMA 2 0 16 O c t 2 7 . d o i: 10 . 10 0 1 /ja m a .2 0 1 6 .1 6 1 4 1 .

A randomized, double-blind, placebo-controlled trial found that giving cranberry capsules to elderly women residing in nursing homes did not result in any significant benefits, including no reduction in symptomatic urinary tract infections.

Tags: 2016, Aged, Bacteriuria – Prevention and Control – In Old Age, Cranberry Juice – Therapeutic Use, Department of Internal Medicine, Female, Human, Infectious Disease Alert, NEOMED College of Medicine, Treatment Outcomes, Urinary Tract Infections – Prevention and Control – In Old Age, Watkins Richard R

Cranberry Capsules Are Not Effective in Preventing Bacteriuria with Pyuria in Elderly Women in Nursing Homes.

A randomized, double-blind, placebo-controlled trial found that giving cranberry capsules to elderly women residing in nursing homes did not result in any significant benefits, including no reduction in symptomatic urinary tract infections.

Risk factors associated with Clostridium difficile diarrhea in hospitalized adult patients: a case-control study–sucralfate ingestion is not a negative risk factor.

OBJECTIVES: To assess risk factors associated with Clostridium difficile diarrhea in hospitalized adult patients, and to test the hypothesis that sucralfate ingestion is associated with nondetection of C difficile cytotoxin in stool specimens.…

Overexpression of beta-catenin and cyclinD1 predicts a poor prognosis in ovarian serous carcinomas.

UNLABELLED: Ovarian serous cancer is the most common subtype of epithelial ovarian cancer, and is the leading cause of death from gynecologic cancer. There is an important need for exploration of diagnostic and prognostic markers for this disease.…

Quality of life, symptoms and care needs in patients with persistent or recurrent platinum-resistant ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study.

OBJECTIVES: The goals of treating recurrent platinum-resistant ovarian cancer are palliative, aimed at reducing symptoms and improving progression free survival. A prospective trial was conducted to determine the prevalence and severity of symptoms,…

Chemotherapy completion in elderly women with ovarian, primary peritoneal or fallopian tube cancer - An NRG oncology/Gynecologic Oncology Group study.

PURPOSE: A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline Instrumental Activities of Daily Living (IADL) score with ability to complete 4 cycles of first line…

Biomechanical Head-to-Head Comparison of 2 Sutures and the Giftbox Versus Bunnell Techniques for Midsubstance Achilles Tendon Ruptures.

BACKGROUND: Acute midsubstance Achilles tendon ruptures are a common orthopaedic problem for which the optimal repair technique and suture type remain controversial. Head-to-head comparisons of current fixation constructs are needed to establish…

Percutaneous Kirschner Wire Repair of Failed Digital Arthrodesis Using Pulsed Electromagnetic Field Therapy A Case Report.

A case of a repaired failed toe arthrodesis is presented. A novel and previously unreported approach using a percutaneously placed Kirschner wire coupled with a pulsed electromagnetic field achieved healing of a painful pseudoarthrosis at 54 days.…

Tags: 2018, Abdelmagid Samir M, Aged, Arthrodesis – Adverse Effects, Female, Hammer Toe Syndrome – Diagnosis, Hammer Toe Syndrome – Surgery, Journal of the American Podiatric Medical Association, Magnet Therapy – Methods, Orthopedic Fixation Devices, Radiography, Reoperation, Toe Joint, Toe Joint – Surgery, Treatment Failure, Unsdorfer Kyle M L

Magnesium disorders: what to do when homeostasis goes awry.

Hypomagnesemia may be caused by renal losses (often related to drugs or diabetes), inadequate intake or inadequate intestinal absorption. Manifestations may include arrhythmias, particularly during myocardial ischemia or with digitalis use, and such…

Low thigh muscle mass is associated with coronary artery stenosis among

BACKGROUND: HIV-infected individuals are at increased risk for both sarcopenia and cardiovascular disease. Whether an association between low muscle mass and subclinical coronary artery disease (CAD) exists, and if it is modified by HIV serostatus,…

Tags: *Computed Tomography Angiography, *Tomography, 2018, Aged, Atherosclerotic, Body Composition, Brown Todd T, Budoff Matthew J, Chi-Square Distribution, Coronary Angiography/*methods, Coronary Artery Disease/*diagnostic imaging/epidemiology/pathology, Coronary artery stenosis, Coronary atherosclerosis, Coronary Stenosis/*diagnostic imaging/epidemiology/pathology, Coronary Vessels/*diagnostic imaging/pathology, Cross-Sectional Studies, Guallar Eliseo, HIV Infections/diagnosis/*epidemiology, HIV-Infection, Humans, Jacobson Lisa P, Journal of cardiovascular computed tomography, Koletar Susan L, Korada Sai Krishna C, Male, Margolick Joseph B, Michos Erin D, Middle Aged, Multivariate Analysis, Muscle, Muscle mass, Odds Ratio, Palella Frank J Jr, Plaque, Post Wendy S, Predictive Value of Tests, Prevalence, Prospective Studies, Risk Factors, Sarcopenia, Sarcopenia/*diagnostic imaging/epidemiology/physiopathology, Saxena Ankita, Skeletal/*diagnostic imaging/physiopathology, Thigh, Tibuakuu Martin, United States/epidemiology, Witt Mallory D, X-Ray Computed, Zhao Di

A histologic review of 27 patients with lichen planopilaris.

BACKGROUND: Lichen planopilaris (LPP) is a potential trichologic emergency that can result in permanent scarring alopecia. Histopathology is a key component of the diagnostic work-up. OBJECTIVE: To identify the key histologic features that…

Tags: 2008, Adult, Aged, Alopecia/etiology/*pathology, Bergfeld Wilma F, Biopsy, Cevasco Nathaniel C, Cicatrix/etiology/*pathology, Female, Humans, Journal of the American Academy of Dermatology, Lichen Planus/complications/diagnosis/*pathology, Male, Middle Aged, Retrospective Studies, Scalp Dermatoses/diagnosis/*pathology, Scalp/*pathology, Somani Najwa, Tandon Yasmeen K

Common fungal infections of the feet in patients with diabetes mellitus.

Superficial fungal infections of the foot (tinea pedis and onychomycosis) are common among elderly patients. Although most authorities believe that patients with diabetes mellitus have an increased predisposition to dermatophytic infections, some…

Tags: *Diabetes Complications, *Onychomycosis/diagnosis/drug therapy/physiopathology, *Tinea Pedis/diagnosis/drug therapy/physiopathology, 2004, Aged, Antifungal Agents/adverse effects/pharmacokinetics/*therapeutic use, Arthrodermataceae/*pathogenicity, Biological Availability, Diabetes Mellitus/drug therapy, Drug Interactions, Drugs & aging, Humans, Hypoglycemic Agents/therapeutic use, Joseph Warren S, Metabolic Clearance Rate, Randomized Controlled Trials as Topic, Tan James S

Can aggressive treatment of diabetic foot infections reduce the need for above-ankle amputation?

We retrospectively evaluated the charts of 112 patients with diabetic foot infection to determine if early aggressive surgical intervention improves outcome. All patients were classified into two groups on the basis of the timing of surgical…

The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study).

BACKGROUND: Deficient levels of 25-hydroxyvitamin D [25(OH)D] have been associated with increased fracture risk. Racial differences in fracture risk may be related to differences in bioavailable vitamin D due to single nucleotide polymorphism (SNP)…

Frailty defined by the SHARE Frailty Instrument and adverse outcomes after an ED visit.

Rectal trauma and associated hemorrhage with the use of the ConvaTec Flexi-Seal fecal management system: report of 3 cases.

The management of fecal incontinence is a struggle to maintain patient hygiene and limit the transmission of nosocomial infections. Intrarectal devices that cause diversion and collection of the fecal stream have been used with increasing frequency.…

Tags: 2010, Aged, Catheterization/*adverse effects/*instrumentation, Chase Daniel, Coughlin Lisa, Diseases of the colon and rectum, Fecal Incontinence/*therapy, Female, Gastrointestinal Hemorrhage/*etiology/surgery, Heaton Bren, Hemostasis, Humans, Male, Metha Jeet, Middle Aged, Pressure Ulcer/*etiology/surgery, Rectum/*injuries/surgery, Sparks Dorothy, Surgical/methods

Cholesteatoma of the maxillary sinus: a case report and review of the literature.

Cholesteatoma is a relatively common disease entity within the middle ear cavity, but it is rarely found in the paranasal sinuses. We describe a rare case of cholesteatoma in the maxillary sinus of an elderly man presenting with recurrent sinus…

Tags: 2015, Aged, American journal of otolaryngology, Cholesteatoma/*diagnosis/*surgery, Endoscopy/methods, Follow-Up Studies, Humans, Josephson Jordan S, Male, Maxillary Sinus/*pathology, Nasal Obstruction/diagnosis/etiology, Paranasal Sinus Diseases/*diagnosis/*surgery, Rare Diseases, Recurrence, Sinusitis/diagnosis/etiology, Sozansky Jeanie, Treatment Outcome

Sonographic Elastography of Mastitis.

Sonographic elastography has been shown to be a useful imaging modality in characterizing breast lesions as benign or malignant. However, in preliminary research, mastitis has given false-positive findings on both strain and shear wave elastography.…

Sonoelastography of Breast Lymphoma.

Breast lymphomas only account for approximately 0.15% of malignant breast carcinomas. Half of these are primary lymphomas, and the other half are metastatic to the breast. Ultrasound elastography has been proven to aid in the diagnosis of breast…

Prevalence and Predictors of Metformin Prescribing in Adults with Type 2 Diabetes Mellitus: A National Cross-Sectional Study.

OBJECTIVE: Metformin is the first-line oral type 2 diabetes treatment. Despite an abundance of evidence, metformin is routinely underused. This study evaluated the rates of metformin use in an appropriate outpatient type 2 diabetes population and…

A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.

Prox1, an early specific marker for developing liver and pancreas in foregut endoderm has recently been shown to interact with alpha-fetoprotein transcription factor and repress cholesterol 7alpha-hydroxylase (CYP7A1) gene transcription. Using a…

Tags: *Gene Expression Regulation, 2006, Aged, Amino Acid Motifs, Bile Acids and Salts/metabolism, Cell Line, Cell Nucleus/metabolism, Cells, Chiang John Y L, Cholesterol 7-alpha-Hydroxylase/*chemistry/*genetics, Cultured/metabolism, Department of Integrative Medical Sciences, Enzymologic, Female, Genes, Genetic, Gluconeogenesis, Glutathione Transferase/metabolism, Hepatocyte Nuclear Factor 4/metabolism/*physiology, Hepatocytes/metabolism, Homeodomain Proteins/metabolism/*physiology, Humans, Immunoprecipitation, Li Tiangang, Liver/metabolism, Luciferases/metabolism, Male, Messenger/metabolism, Middle Aged, NEOMED College of Medicine, Phosphoenolpyruvate Carboxykinase (ATP)/metabolism, Plasmids/metabolism, Protein Structure, Reporter, Response Elements, Reverse Transcriptase Polymerase Chain Reaction, RNA, Small Interfering/metabolism, Song Kwang-Hoon, Tertiary, The Journal of biological chemistry, Time Factors, Transcription, Transcriptional Activation, Transfection, Tumor Suppressor Proteins, Two-Hybrid System Techniques

Relationship between breast cancer and meningioma.

Several authors have suggested the existence of a relationship between breast cancer and meningioma occurring in the same patient. I describe four patients who had both of these neoplasms and present findings that dispute the implied relationship…

Tags: 1992, Aged, Breast Neoplasms/*diagnosis, Carcinoma, Female, Humans, Intraductal, Meningeal Neoplasms/*diagnosis, Meningioma/*diagnosis, Middle Aged, Neoplasms, Noninfiltrating/*diagnosis, Ovarian Neoplasms/diagnosis, Second Primary/*diagnosis, Smith-Behn J, Southern medical journal, Time Factors

A Review of Treatment for Breast Cancer-Related Lymphedema: Paradigms for Clinical Practice.

OBJECTIVES: Breast cancer-related lymphedema (BCRL) represents a major complication of breast cancer treatment, impacting the quality of life for breast cancer survivors that develop it. The purpose of this review is to evaluate the literature…

Recognition of depression by internal medicine residents.

We studied the ability of internal medicine residents to recognize depressive symptoms in a population of lower socio-economic primary care patients. Four hundred twenty patients completed the short form of the Beck Depression Inventory (BDI).…

Cyanide toxicity in the surgical intensive care unit: a case report.

Hypertension is a widespread entity in the surgical intensive care unit. Not only is the clinical spectrum varied, but the armamentarium available to the clinician is also wide-ranging. Sodium nitroprusside, a potent vasodilator with a short…

Tags: 2001, Aged, Cyanides/*poisoning, Female, Humans, Hypertension/complications/*drug therapy, Intensive Care Units, Nitroprusside/administration & dosage/pharmacokinetics/*poisoning, Poisoning/diagnosis/therapy, Porter J M, Sipe E K, The American surgeon, Trienski T L, Wounds and Injuries/complications/therapy

Freestanding emergency departments and the trauma patient.

BACKGROUND: Freestanding emergency departments (FEDs) continue to grow in number and more research is needed on these facilities. OBJECTIVE: We sought to characterize the types of injuries and patients who initially presented to two FEDs and were…

Improved auscultation skills in paramedic students using a modified stethoscope.

Dual-catheter covered stenting: a novel approach to the treatment of large coronary artery perforations.

Coronary perforation is an infrequent but potentially devastating complication of coronary intervention. Treatment of a broad-based perforation usually requires emergent pericardiocentesis and thoracotomy. We present a novel approach to closure of…

Pyoderma gangrenosum complicated by underlying osteomyelitis: successful treatment with radical surgical debridement and cyclosporine therapy.

Tags: 1995, Aged, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Cyclosporine/*therapeutic use, Debridement, Female, Follow-Up Studies, Humans, Leg Ulcer/complications/surgery/*therapy, Osteomyelitis/*complications/therapy, Pseudomonas Infections/*complications/therapy, Pyoderma Gangrenosum/complications/surgery/*therapy, Signs D J, Wagner D S

An institutional series and contemporary review of bacterial spinal epidural abscess: current status and future directions.

OBJECT: Over the past decade, the incidence of bacterial spinal epidural abscess (SEA) has been increasing. In recent years, studies on this condition have been rampant in the literature. The authors present an 11-year institutional experience with…

Solitary lesion on the left ankle.

Tags: 2015, Aged, Ankle, Cutis, Department of Internal Medicine, Diagnosis, Differential, Humans, Male, Mostow Eliot N, NEOMED College of Medicine, Porokeratosis/*diagnosis/pathology, Shenoy Renuka

The medically underserved: who is likely to exercise and why?

Adults who exercise regularly have better health, but only 15% of U.S. adults engage in regular exercise, with some social groups, such as people with lower incomes and women, having even lower rates. This study investigates the rate at which…

The medically underserved: who is likely to exercise and why?

Adults who exercise regularly have better health, but only 15% of U.S. adults engage in regular exercise, with some social groups, such as people with lower incomes and women, having even lower rates. This study investigates the rate at which…

Lumbar spine fractures within a complete American cohort: epidemiology and risk factors among military service members.

STUDY DESIGN: Retrospective database review. OBJECTIVE: To describe the incidence of, and risk factors for, lumbar spine fractures within the population of the US military. SUMMARYOF BACKGROUND DATA: Fractures of the lumbar region are an important…

The effect of race on outcomes of surgical or nonsurgical treatment of patients in the Spine Patient Outcomes Research Trial (SPORT).

STUDY DESIGN: Retrospective review of the data collected prospectively through the Spine Patient Outcomes Research Trial (SPORT). OBJECTIVE: To determine the effect that race or ethnicity had on outcomes after spine surgery in the 3 arms of SPORT.…

Outcomes of modular proximal femoral replacement in the treatment of complex proximal femoral fractures: a case series.

BACKGROUND: The treatment of complex femur fractures poses a significant challenge. Even with current advancements and the various implements available for the fixation of femoral fractures, results are often disappointing. This study sought to…

Characterization of the incidence and risk factors for the development of lumbar radiculopathy.

STUDY DESIGN: Epidemiological study of a prospectively collected database. OBJECTIVES: This investigation sought to evaluate the incidence of symptomatic lumbar radiculopathy, and identify risk factors for its development, among individuals serving…

Mortality in elderly patients with hyperostotic disease of the cervical spine after fracture: an age- and sex-matched study.

BACKGROUND CONTEXT: Several reports indicate that patients with ankylosing spondylitis (AS) and diffuse idiopathic skeletal hyperostosis (DISH) have increased mortality after cervical spine fractures. However, outcomes of the fractured hyperostotic…

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