Browse Items · NEOMED Bibliography Database

Thrombospondin-4 mediates TGF-beta-induced angiogenesis.

TGF-beta is a multifunctional cytokine affecting many cell types and implicated in tissue remodeling processes. Due to its many functions and cell-specific effects, the consequences of TGF-beta signaling are process-and stage-dependent, and it is not…

Thirty-Day Readmissions After Transcatheter Aortic Valve Replacement in the United States: Insights From the Nationwide Readmissions Database.

BACKGROUND: Readmissions after cardiac procedures are common and contribute to increased healthcare utilization and costs. Data on 30-day readmissions after transcatheter aortic valve replacement (TAVR) are limited. METHODS AND RESULTS: Patients…

Tags: *aortic stenosis, *costs and cost analysis, *length of stay, *Patient Readmission/economics, *readmission, *rehospitalization, *transcatheter aortic valve implantation, *transcatheter aortic valve replacement, 2017, 80 and over, Abbott J Dawn, Aged, Aortic Valve Stenosis/diagnosis/economics/*surgery, Aronow Wilbert S, Bhatt Deepak L, Chatterjee Saurav, Circulation. Cardiovascular interventions, Comorbidity, Databases, Department of Internal Medicine, Factual, Female, Fonarow Gregg C, Gheewala Neil, Goldsweig Andrew, Gordon Paul C, Greenbaum Adam B, Gupta Tanush, Hospital Costs, Humans, Khera Sahil, Kolte Dhaval, Length of Stay, Male, NEOMED College of Medicine, Patient Discharge, Postoperative Complications/etiology, Risk Factors, Sardar M Rizwan, Sharaf Barry, Skilled Nursing Facilities, Time Factors, Transcatheter Aortic Valve Replacement/*adverse effects/economics, Treatment Outcome, United States

Therapeutic Delivery of Simvastatin Loaded in PLA-PEG Polymersomes Resulted in Amplification of Anti-inflammatory Effects in Activated Microglia.

Simvastatin (Sim), a lipid-lowering drug has been studied in chronic neuroinflammation associated with degenerative brain disorders due to its potential protective properties against inflammatory reaction, oxidative damage, neuronal dysfunction, and…

The versatility and paradox of GDF 11.

In addition to its roles in embryonic development, Growth and Differentiation Factor 11 (GDF 11) has recently drawn much interest about its roles in other processes, such as aging. GDF 11 has been shown to play pivotal roles in the rescue of the…

The utility of hair cortisol concentrations in the prediction of PTSD symptoms following traumatic physical injury.

RATIONALE: Although cortisol alterations have been associated with posttraumatic stress disorder (PTSD) and PTSD symptoms (PTSS), the direction of association is mixed. Cortisol which is measured in blood, saliva, or urine is subject to transient…

The Use of Substances Other Than Nicotine in Electronic Cigarettes Among College Students.

INTRODUCTION: Electronic cigarettes (e-cigarettes) have grown in popularity, especially among youth and young adults. Although e-cigarettes were originally intended to vaporize a liquid mixture containing nicotine, there appears to be an increasing…

The Unraveling of the Matryoshka Doll.

Tags: *chemokines, *exosomes, *heart failure, *Myocardial infarction, *Stem cells, 2017, Adult, Adult Stem Cells/metabolism/*transplantation, Circulation research, Exosomes/genetics/metabolism, Gene Expression, Heart Diseases/physiopathology/*therapy, Humans, MicroRNAs/genetics/metabolism, Penn Marc S, Regenerative Medicine/methods/trends, Stem Cell Transplantation/*methods

The Unraveling of the Matryoshka Doll.

Tags: 2017, chemokines, Circulation research, Exosomes, Heart failure, myocardial infarction, Penn Marc S, stem cells

The Role Of Leptin In Coronary Collateral Growth

Tags: 2017, Biochemistry & Molecular Biology, Cell Biology, Chilian W M, Enrick M, Faseb Journal, Graham K, Journal Article or Conference Abstract Publication, Kolz C, Life Sciences & Biomedicine - Other, Ohanyan V, Topics, Yin L Y

The Role Of Amadori-glycation In High Density Lipoprotein Dysfunction And Oxidative Stress In Patients With Diabetes

Tags: 2017, Apolipoproteins, Arteriosclerosis Thrombosis and Vascular Biology, Atherosclerosis, Cardiovascular System & Cardiology, Department of Pharmaceutical Sciences, Golizeh M, Hematology, Ilchenko S, Insulin Resistance, Journal Article or Conference Abstract Publication, Kashyap S, Kasumov T, Lee K, NEOMED College of Pharmacy, Smith J, Wang S H

The power of great expectations.

Tags: 2017, Accreditation, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, Awards and Honors, expectations, Goals and Objectives, high performance, Hunt Max L Mick Jr, Intraprofessional Relations, Leadership, Management, pharmacy administration, Pharmacy Technicians, Philosophy, Public Speaking, Technology

The JCR:LA-cp rat: a novel rodent model of cystic medial necrosis.

Although there are multiple rodent models of the metabolic syndrome, very few develop vascular complications. In contrast, the JCR:LA-cp rat develops both metabolic syndrome and early atherosclerosis in predisposed areas. However, the pathology of…

The Hidden Value of Variation in Practice.

Tags: 2017, Antibiotics, Antibiotics – Administration and Dosage, CHILDREN'S hospitals, CYSTIC fibrosis, Cystic Fibrosis – Drug Therapy, DISEASE exacerbation, Disease Exacerbation – Drug Therapy, Hospitals, Length of Stay, LENGTH of stay in hospitals, LUNG diseases, Lung Diseases – Drug Therapy, McBride John T, Pediatric, Pediatrics, Stokes Dennis C

The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship-results from an international cross-sectional survey.

BACKGROUND: Antimicrobial Stewardship Programs (ASPs) have been promoted to optimize antimicrobial usage and patient outcomes, and to reduce the emergence of antimicrobial-resistant organisms. However, the best strategies for an ASP are not…

Tags: *Antibiotics, *Antimicrobial stewardship, *Infections, *Surgery, 2017, Abbo Lilian M, Abu-Zidan Fikri M, Academic Medical Centers, Adesunkanmi Abdulrashid K, Al-Dahir Sara, Al-Hasan Majdi N, Alis Halil, Alves Carlos, Ansaloni Luca, Anti-Infective Agents/*therapeutic use, Antibiotic Prophylaxis, Antiinfective Agents – Therapeutic Use, Antimicrobial Stewardship/*methods, Araujo da Silva Andre R, Audit, Augustin Goran, Bala Miklosh, Barbadoro Pamela, Barie Philip S, Beltran Marcelo A, Bhangu Aneel, Bouchra Belefquih, Brecher Stephen M, Brink Adrian J, Cainzos Miguel A, Camacho-Ortiz Adrian, Carlet Jean, Catani Marco, Catena Fausto, Chandy Sujith J, Cherry-Bukowiec Jill R, Chiara Osvaldo, Chichom-Mefire Alain, Coccolini Federico, Colak Elif, Communicable Diseases, Community, Cornely Oliver A, Cross Sectional Studies, Cross-Sectional Studies, Cui Yunfeng, Culture, Data Analysis Software, De Simone Belinda, de Souza Hamilton P, De Waele Jan J, Demetrashvili Zaza, Department of Internal Medicine, Descriptive Statistics, Dhingra Sameer, Di Marzo Francesco, Di Saverio Salomone, Dogjani Agron, Dorj Gereltuya, Dortet Laurent, Duane Therese M, Education, Elmangory Mutasim M, Enani Mushira A, Esteban Foianini J, Female, Ferrada Paula, Gachabayov Mahir, Gandhi Chinmay, Ghnnam Wagih Mommtaz, Giamarellou Helen, Gkiokas Georgios, Global Health/trends, Gomi Harumi, Goranovic Tatjana, Griffiths Ewen A, Guerra Gronerth Rosio I, Haidamus Monteiro Julio C, Hardcastle Timothy C, Hecker Andreas, Hodonou Adrien M, Hospitals, Human, Humans, Infection – Prevention and Control, Infection Control – Methods, International Agencies, Intraabdominal Infections/*drug therapy, Ioannidis Orestis, Isik Arda, Iskandar Katia A, Jusoh Asri Che, Kafil Hossein S, Kanj Souha S, Kaplan Lewis J, Kapoor Garima, Karamarkovic Aleksandar R, Kenig Jakub, Kerschaever Ivan, Khamis Faryal, Khanna Ashish, Khokha Vladimir, Kiguba Ronald, Kim Hong B, Ko Wen-Chien, Koike Kaoru, Kozlovska Iryna, Kumar Anand, Labricciosa Francesco M, Lagunes Leonel, Latifi Rifat, Lee Jae G, Lee Young R, Leppaniemi Ari, Li Yousheng, Liang Stephen Y, Lowman Warren, Machain Gustavo M, Maegele Marc, Major Piotr, Malama Sydney, Male, Manzano-Nunez Ramiro, Marinis Athanasios, Martinez Casas Isidro, Marwah Sanjay, Maseda Emilio, May Addison K, McFarlane Michael E, Medical Organizations, Medical Practice, Memish Ziad, Mertz Dominik, Mesina Cristian, Microbiology, Mishra Shyam K, Moore Ernest E, Multidisciplinary Care Team, Munyika Akutu, Mylonakis Eleftherios, Napolitano Lena, Negoi Ionut, NEOMED College of Medicine, Nestorovic Milica D, Nicolau David P, Omari AbdelKarim H, Operative, Ordonez Carlos A, Pagani Leonardo, Paiva Jose-Artur, Pant Narayan D, Parreira Jose G, Pedziwiatr Michal, Pereira Bruno M, Pereira Nuno Rocha, Policy Making, Ponce-de-Leon Alfredo, Postoperative Complications/*drug therapy, Poulakou Garyphallia, Preller Jacobus, Preoperative Care, Pulcini Celine, Pupelis Guntars, Quiodettis Martha, Rawson Timothy M, Reis Tarcisio, Rems Miran, Resource Allocation, Rizoli Sandro, Roberts Jason, Rodriguez-Bano Jesus, Rural Areas, Sakakushev Boris, Sanders James, Santos Natalia, Sartelli Massimo, Sato Norio, Sawyer Robert G, Scarpelini Sandro, Scoccia Loredana, Scudeller Luigia, Shafiq Nusrat, Shelat Vishalkumar, Sifri Costi D, Siribumrungwong Boonying, Soreide Kjetil, Soto Rodolfo, Specialization, Surgery, Surgical Wound Infection – Therapy, Surveys and Questionnaires, Talving Peep, Tessier Jeffrey M, Trung Ngo Tat, Tumbarello Mario, Ulrych Jan, Uranues Selman, Urban Areas, van Goor Harry, Vereczkei Andras, Viale Pierluigi, Wagenlehner Florian, Watkins Richard R, Wechsler-Fordos Agnes, World journal of emergency surgery : WJES, Xiao Yonghong, Yuan Kuo-Ching, Zahar Jean-Ralph, Zakrison Tanya L, Zuckerbraun Brian, Zuidema Wietse P

The First Evidence Of Osteomyelitis In A Sauropod Dinosaur

The cost of interoperability.

The article looks at an interoperability report by the U.S. Government Accountability Office (GAO) on the status of efforts to develop infrastructure that could lead to nationwide interoperability of health information. Topics covered include five…

Tags: 2017, Cause of Death, Death Certificates, Electronic Data Interchange, Health Care Errors, Health Facility Administration, Health Management Technology, International Classification of Diseases, Patient Record Systems, Software, Voltz Donald

The contribution of interleukin-2 to effective wound healing.

Ineffective skin wound healing is a significant source of morbidity and mortality. Roughly 6.5 million Americans experience chronically open wounds and the cost of treating these wounds numbers in the billions of dollars annually. In contrast, robust…

The CARE approach to reducing diagnostic errors.

BACKGROUND: Diagnostic errors appear to be the most common, costly, and dangerous of all medical mistakes. There has been a notable increase on the focus of error prevention as part of a growing patient safety movement. However, diagnostic errors…

THE BONE MARROW ENDOTHELIAL PROGENITOR CELL RESPONSE TO SYSTEMIC ESCHERICHIA COLI INFECTION

Tags: & Cardiology, 2017, Cardiovascular System, General & Internal Medicine, Hematology, Journal Article, Shi X, Shock, Surgery, Zhang P

The Association Between Daily Ptsd Symptom Severity And Alcohol-related Outcomes In Recent Traumatic Injury Victims

The self-medication hypothesis proposes that individuals experiencing posttraumatic stress disorder (PTSD) symptoms may use alcohol (or other substances) to self-medicate distress, while the mutual maintenance hypothesis proposes that alcohol use…

The Almost Right Word: The Move From Medical to Health Humanities.

Since the emergence of the field in the 1970s, several trends have begun to challenge the original assumptions, claims, and practices of what became known as the medical humanities. In this article, the authors make the case for the health humanities…

Tags: *Health, *Medicine, *Terminology as Topic, 2017, Academic medicine : journal of the Association of American Medical Colleges, Blackie Michael, Curriculum, Department of Family & Community Medicine, Garden Rebecca, Humanities/*education, Humans, Interdisciplinary Studies, Jones Therese, NEOMED College of Medicine, Wear Delese

Temperature-sensitive Medications in Interfacility Transport: The Ice Pack Myth.

INTRODUCTION: Critical Care Transport teams use various strategies to maintain temperature sensitive drugs and equipment at optimal temperature. The purpose of this study was to examine the effectiveness of current passive refrigeration of…

Targetting Cysteinyl Leukotriene 2 Receptor as a Therapeutic Target for Tumor Growth and Metastasis: A New Function for an Old Receptor

Tags: 2017, Adapala R, Al-Azzam N Z, Biochemistry & Molecular Biology, Cell Biology, Duah E, Faseb Journal, Ghebreigziabher S, Journal Article, Kondeti V, Life Sciences & Biomedicine - Other, Paruchuri S, Teegala L R, Thodeti C, Topics

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a

BACKGROUND & AIMS: Hepatic cholesterol accumulation and autophagy defects contribute to hepatocyte injury in fatty liver disease. Bile acid synthesis is a major pathway for cholesterol catabolism in the liver. This study aims to understand the…

Tags: 2017, 4EBP-1, ACAT, acyl-CoA:cholesterol acyltransferase, CE, Cellular and molecular gastroenterology and hepatology, Chavan Hemantkumar, Chiang John Y L, chloroquine, Cholesterol, cholesterol 7alpha-hydroxylase, cholesterol ester, Cholestyramine, ChTM, CQ, CYP7A1, Department of Integrative Medical Sciences, diet-induced obesity, Ding Wen-Xing, Ding Yifeng, DIO, endoplasmic reticulum, ER, eukaryotic translation initiation factor 4E-binding protein 1, Fatty Liver, FC, free cholesterol, glycogen synthase kinase 3beta, GSK3beta, HMG-CoA reductase, HMGCR, Krishnamurthy Partha, LC3, LDLR, Li Jibiao, Li Tiangang, LMP, low-density lipoprotein receptor, lysosome membrane permeabilization, Matye David, messenger RNA, microtubule-associated protein 1A/1B-light chain 3, mRNA, mTOR, NEOMED College of Medicine, Ni Hong-Min, Nuclear Receptor, phosphatidylinositol, PI, plasma membrane, PM, S6, SREBP, sterol response element binding protein, the nutrient sensing mechanistic target of rapamycin, tibosomal protein S6, Wang Yifeng

Targeting bile acids and lipotoxicity for NASH treatment.

Tags: 2017, Chiang John Y L, Department of Integrative Medical Sciences, Hepatology communications, NEOMED College of Medicine

Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists.

Farnesoid X receptor (FXR), a nuclear receptor mainly distributed in liver and intestine, has been regarded as a potential target for the treatment of various metabolic diseases, cancer and infectious diseases related to liver. Starting from two…

Surprising absence of heparin in the intestinal mucosa of baby pigs.

Heparin, a member of a family of molecules called glycosaminoglycans, is biosynthesized in mucosal mast cells. This important anticoagulant polysaccharide is primarily produced by extraction of the mast cell-rich intestinal mucosa of hogs. There is…

Sucrose, But Not Glucose, Blocks IL1-beta-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.

Pathogenesis of osteoarthritis (OA) is multifactorial but interleukin-1beta (IL-1beta) is known to be an important mediator of cartilage degradation. Autophagy is an essential cellular homeostasis mechanism and has been proposed to protect against…

Subacute Hypersensitivity Pneumonitis: A Case Report

Tags: 2017, American journal of respiratory and critical care medicine, Department of Internal Medicine, Elahee M, General & Internal Medicine, Kalra N P, Kartan R, NEOMED College of Medicine, Respiratory System, Talat A

Su1207 Utility of Small Bowel Balloon Enteroscopy: A Community Hospital Experience...Digestive Disease Week (DDW) 2017 American Society for Gastrointestinal Endoscopy (ASGE) Program and Abstracts, Chicago, Illinois, 6-9 May 2017.

Tags: 2017, Balloon Enteroscopy, Community, Congresses and Conferences, Dodig Milan, Elahee Mehreen, Gastrointestinal Endoscopy, Geisler Thomas, Hospitals, Riordan Adam, Talat Arslan

Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.

Elevated triglycerides (TG) contribute towards increased risk for cardiovascular disease. Lipoprotein lipase (LPL) is an enzyme that is responsible for the metabolism of core triglycerides of very-low density lipoproteins (VLDL) and chylomicrons in…

Strain Elastography - How To Do It?

Tissue stiffness assessed by palpation for diagnosing pathology has been used for thousands of years. Ultrasound elastography has been developed more recently to display similar information on tissue stiffness as an image. There are two main types of…

Tags: 2017, Barr Richard G, Dietrich Christoph F, Dighe Manjiri, Dong Yi, endoscopic ultrasound, Farrokh Andre, Havre Roald Flesland, Hocke Michael, Jenssen Christian, real-time, Saftoiu Adrian, tissue elastography (TE), Ultrasound, Ultrasound international open

Stereotype threat as a barrier to women entering engineering careers

Theory suggests that proximal contextual variables contribute to women's underrepresentation in STEM fields. We therefore examined relationships between stereotype threat as a proximal contextual variable and academic self-efficacy. We also examined…

Statin Use Is Associated With a Lower Risk of Community-acquired Staphylococcus aureus Bacteremia.

A population-based case-control study from Denmark found the use of statins was associated with a decreased risk for community-associated Staphylococcus aureus bacteremia, with the greatest benefit from higher doses.

Tags: 2017, Bacteremia – Risk Factors, Biofilms – Drug Effects, Cell Physiology – Drug Effects, Community-Acquired Infections – Drug Therapy, Department of Internal Medicine, Drug Resistance, Infectious Disease Alert, Microbial, NEOMED College of Medicine, Neutrophils, Risk Assessment, Simvastatin – Administration and Dosage, Staphylococcus Aureus – Drug Effects, Statins – Economics, Statins – Therapeutic Use, Watkins Richard R

Staphylococcus Lugdunensis: The "lyon Heart" Pathogen Report Of 5 Cases Of Endocarditis And Review Of The Adult Literature

Staphylococcus lugdunensis is a coagulase-negative Staphylococcus capable of causing infective endocarditis on native as well as prosthetic valves and implanted cardiac devices. It causes acute disease clinically indistinguishable from that caused by…

Tags: 2017, bacteremia, Byrnes T J, clinical-experience, Immunology, Infectious Diseases, Infectious Diseases in Clinical Practice, infective endocarditis, Journal Article or Conference Abstract Publication, Kline J A, lead endocarditis, Myers J P, native-valve, of-the-literature, Pacemaker, prosthetic valve, pulmonary valve endocarditis, Staphylococcus lugdunensis, Vasectomy

Spinal angiolipomas: A puzzling case and review of a rare entity.

Patients with spinal epidural abscesses (SEAs) may have a variable presentation. Such an infection has a typical appearance on magnetic resonance imaging (MRI) and enhances with gadolinium. We present a case that was a diagnostic challenge where pre-…

Tags: 2017, Angiolipoma, back pain, Chopko Bohdan, epidural abscess, Journal of craniovertebral junction & spine, Magnetic Resonance Imaging, Sangtani Ajleeta, Shweikeh Faris, spinal cord compression, spine neoplasms, Steinmetz Michael P, Zahos Peter

Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice.

Nuclear receptors farnesoid X receptor (FXR) and small heterodimer partner (SHP) are important regulators of bile acid, lipid, and glucose homeostasis. Here, we show that global Fxr (-/-) Shp(-/-) double knockout (DKO) mice are refractory to weight…

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